An observational study in Epilepsy and Epilepsy, Idiopathic Generalized, sponsored by Shen Chun-Hong. Recruiting at 1 site in China. Open to participants aged 4 Years to 40 Years. Per ClinicalTrials.gov, last updated 2025-08-27.
Sponsored by Shen Chun-Hong · Observational
The idiopathic generalized epilepsies (IGEs) have historically included the syndromes childhood absence epilepsy (CAE), juvenile absence epilepsy (JAE), juvenile myoclonic epilepsy (JME), and epilepsy with generalized tonic-clonic seizures alone (GTCA). Recognition of the IGEs is important for clinical care, as it informs diagnosis, prevents unnecessary investigation, allows optimal selection of anti-seizure medications (ASMs), and provides prognostic guidance.
According to the new ILAE definition in 2022, the study aims to describe the clinical features, electroencephalographic, imaging findings and long-term prognosis.
the Long-term prognosis include the rate of drug-resistent epilepsy, relapse after drug withdrawn, common comorbidities such as mood disorders, attention deficit hyperactivity disorder (ADHD) and learning disabilities.
1,805 studies on the registry are indexed under Epilepsy; 417 are open to participants now.
This study's planned enrollment of 200 is above the median of 102 across 521 observational studies indexed under Epilepsy.
Browse Epilepsy studies →Shen Chun-Hong is the lead sponsor of 4 studies on the registry; 3 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Patients are consecutively and prospectively recruited from epilepsy center and clinics
Exclusion Criteria:
The proportion of drug-resistent epilepsy
We defined drug-resistant cases as those patients who have failed two or more trials of broad-spectrum ASMs or those otherwise indicated in IGE syndromes
Time frame: through study completion, an average of 1 year
The proportion of seizure freedom
We defined seizure freedom according to the International League Against Epilepsy (ILAE) definition
Time frame: through study completion, an average of 1 year
The proportion of psychiatric comorbidity
The psychiatric comorbidities mainly include anxiety and depression, which are evaluated by Hamilton anxiety scale and Hamilton depression scale, respectively.
Time frame: through study completion, an average of 1 year
The proportion of psychosocial outcome
such as university entrance, marry
Time frame: through study completion, an average of 1 year
The proportion of seizure relapse after antiseizure medication withdrawn
Antiseizure medication withdrawn should be recommended by epilepsy experts
Time frame: through study completion, an average of 1 year
Plan to share: No
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Shen Chun-Hong