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CompletedNCT05496439Updated Aug 11, 2022

Study of the Prognosis of Patients With Heart Failure With Preserved Ejection Fraction

An observational study in Heart Failure With Preserved Ejection Fraction, sponsored by Chongqing Medical University. Completed at 1 site in China. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2022-08-11.

Sponsored by Chongqing Medical University · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
172
Ages
18 Years and older
Sex
All
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Study summary

Study of the prognosis of patients with heart failure with preserved ejection fraction

Read the detailed description

Obesity is an independent risk factor for heart failure with preserved ejection fraction (HFpEF), however, the impact of visceral fat area (VFA) in patients with HFpEF is unclear. According to established process of patients' selection, a total of 172 patients whose mean age was 72 years were included in this study, and the median follow-up duration was 395.5 days(interquartile range: 207.5 to 535.5 days). All patients were divided into two groups based on the best cut-off value of VFA, and the primary outcome of this study was all-cause death in patients with HFpEF. The aim of this study was to clarify whether VFA has prognostic value in patients with HFpEF by Kaplan-Meier analysis and cox analysis.

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Conditions studied

  • Heart Failure With Preserved Ejection Fraction

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Keywords

  • visceral fat area
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In context

Heart Failure

5,701 studies on the registry are indexed under Heart Failure; 1,220 are open to participants now.

This study's enrollment of 172 is below the median of 200 across 1,679 observational studies indexed under Heart Failure.

Browse Heart Failure studies →

Lead sponsor

Chongqing Medical University is the lead sponsor of 75 studies on the registry; 17 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

patients with heart failure with preserved ejection fraction

Inclusion criteria

  1. Adult aged >=18years old;
  2. Diagnosed with HFpEF.Diagnostic criteria including:

1)left ventricular ejection fraction ≥50%; 2)with the symptoms and/or signs of heart failure; 3)BNP≥35 pg/mL and/or NTproBNP≥125 pg/mL; 4)at least one additional criterion: relevant structural heart disease(LVH and/or LAE) or diastolic dysfunction

Exclusion criteria

Exclusion Criteria:

  1. Age \<18 years old;
  2. LVEF less than 45% at any time;
  3. cancer diagnosis.
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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
172 participants (actual)
Patient registry
No
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What researchers measure

Primary outcomes

  1. death

    all-cause death

    Time frame: The median follow-up time of 395.5 days(interquartile range: 207.5 to 535.5 days)

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Study locations

1 site
  • The First Affiliated Hospital of Chongqing Medical University
    Chongqing, China
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References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 11, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT05496439
Lead sponsor
Chongqing Medical University
Responsible party
Dongying Zhang (clinical professor, Chongqing Medical University) — Principal investigator
First posted
Aug 11, 2022
Start date
Mar 1, 2020
Primary completion
May 22, 2022
Completion
Jul 6, 2022
Last update
Aug 11, 2022

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Aug 2022. You cannot join it, but the record below documents what was studied.

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