An interventional study of Multimodal intervention and Control in Sleep Disturbance, sponsored by Mirjam Münch. Completed at 1 site in Switzerland. Open to participants aged 65 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-07-16.
Sponsored by Mirjam Münch · Not applicable, Interventional, and Other
The main objective of the study is to improve subjective sleep quality using a multimodal intervention with an intervention and a control group. The multimodal intervention aims to improve circadian Zeitgeber strength. This will be achieved by optimizing daily light exposure, sleep, physical activity, and mealtimes.
The study lasts for 14 months and contains 6 visits. After the screening visit at the Centre for Chronobiology, Basel, Switzerland, participants are assigned to either the intervention or the control group which is followed by a 7-day baseline week at home and a co-design meeting to provide instructions to the intervention and the control group. At the occasion of 2 visits (spread over 6 months) at the participants' homes, different measurements will be performed such as saliva collection, questionnaires, cognitive performance tests, light and rest-activity measures. After the last visit at home, participants come for the second blood sample at the study centre. A follow-up visit 6 months after completion of the last data collection will provide qualitative feedback by the participants.
756 studies on the registry are indexed under Parasomnias; 189 are open to participants now.
This study's enrollment of 66 is close to the median of 66 across 569 interventional studies indexed under Parasomnias.
Browse Parasomnias studies →This is the only study on the registry with Mirjam Münch as lead sponsor.
Counted across the registry records on this site, refreshed daily.
at least 65 years old women and men
Exclusion Criteria:
Personalised intervention
Behavioral: Multimodal intervention
General sleep advice
Behavioral: Control
Participants in the intervention group will receive personalised advice on sleep, light exposure, meal times and physical activity.
General sleep advice
Subjective sleep quality
Pittsburgh Sleep Quality Index (Score \> 5 indicates poor sleep)
Time frame: 6 months
Sleep timing
Derived from Activity Watches
Time frame: 6 months
Subjective wellbeing
Visual Analogue Scales
Time frame: 6 months
Salivary melatonin concentration
Circadian phase marker
Time frame: 6 months
Pupil size
Pupil response to chromatic light stimuli
Time frame: 6 months
Glucose metabolism
HbA1c concentration (blood)
Time frame: 6 months
Telomere length
Age marker
Time frame: 6 months
Neuropsychological Battery to assess working memory and attention (including n-back, Psychomotor Vigilance Test)
Cognitive Function
Time frame: 6 months
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Mar 2025. You cannot join it, but the record below documents what was studied.
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