An interventional study of Scheduled Coaching + Gamified Rewards and Scheduled Coaching Calls + Independent Rewards in Disability Physical, Chronic Condition and Chronic Conditions, Multiple, sponsored by University of Alabama at Birmingham. Completed at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-12-18.
Sponsored by University of Alabama at Birmingham · Not applicable, Interventional, and Other
The purpose of this study to pilot test an accessible and inclusive artificial intelligence (AI)-assisted, individualized, family-focused lifestyle modification intervention (AI4CHRON) for health-related quality of life for adults with impaired mobility and chronic medical conditions.
The AI4CHRON study will use a four-arm randomized control trial design. Eligible and consented participants will be assigned to one of four groups: 1) Scheduled coaching calls with gamified rewards, 2) Scheduled coaching calls with rewards independent of gamification, 3) No scheduled coaching calls with gamified rewards, and 4) No scheduled coaching calls with rewards independent of gamification. The active intervention period will be six months.
89 studies on the registry are indexed under Multiple Chronic Conditions; 16 are open to participants now.
This study's enrollment of 212 is above the median of 128 across 71 interventional studies indexed under Multiple Chronic Conditions.
Browse Multiple Chronic Conditions studies →University of Alabama at Birmingham is the lead sponsor of 1,421 studies on the registry; 277 are open to participants now.
Of its 164 completed or terminated interventional studies of FDA-regulated products, 130 (79%) have results posted.
Compared within Multiple Chronic Conditions, this study's primary condition as ClinicalTrials.gg classifies it; the registry's first condition term is Chronic Disease. The counts are of registry records indexed under each term, refreshed daily. How we classify →
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Behavioral: Scheduled Coaching + Gamified Rewards
Behavioral: No Scheduled Coaching Calls + Gamified Rewards
Behavioral: Scheduled Coaching Calls + Independent Rewards
Behavioral: No Scheduled Coaching Calls + Independent rewards
Participants will receive scheduled coaching calls and receive gamified rewards (i.e., earning points over time and converted to monetary gifts)
Participants will receive scheduled coaching calls and receive fixed rewards (i.e., non-increasing)
Participants will not have scheduled coaching calls and receive gamified rewards (i.e., earning points over time and converted to monetary gifts)
Participants will not have scheduled coaching calls and receive fixed rewards (i.e., non-increasing)
Health-related quality-of-life
Enabled version of Short-Form 36 (SF-36E)
Time frame: 24 Weeks
Physical activity
Godin leisure time exercise questionnaire
Time frame: 24 weeks
Usability
System Usability Scale
Time frame: 24 weeks
Usability
Health Information Technology Usability Evaluation Scale
Time frame: 24 weeks
Medication adherence
Medication adherence rating scale
Time frame: 24 weeks
Medication adherence
Turnkey Adherence Strategy Medication Adherence
Time frame: 24 weeks
Self-efficacy for managing depression
PROMIS SF v1.0 Emotional Distress-Depression 4a
Time frame: 24 weeks
Self-efficacy for managing psychosocial illness
PROMIS SF v1.0 Psychosocial illness impact 8a
Time frame: 24 weeks
Self-efficacy for managing emotions
PROMIS SF v1.0 Managing Emotions 4a
Time frame: 24 weeks
Self-efficacy for managing medications
PROMIS SF v1.0 Managing Emotions 4a
Time frame: 24 weeks
Self-efficacy for managing social interactions
PROMIS SF v1.0 Social Interactions 4a
Time frame: 24 weeks
Physical Activity
Measured via data from FitBit device (Minutes)
Time frame: 24 weeks
Physical Activity
Measured via data from FitBit device (Steps)
Time frame: 24 weeks
Self-efficacy for managing symptoms
PROMIS SF v1.0 Managing Symptoms 4a
Time frame: 24 weeks
Self-efficacy for managing daily activities
PROMIS SF v1.0 Managing daily activities 4a
Time frame: 24 weeks
Self-efficacy for managing sleep disturbance
PROMIS SF v1.0 Sleep Disturbance 4a
Time frame: 24 weeks
Self-efficacy for managing sleep-related impairments
PROMIS SF v1.0 Sleep-related impairment
Time frame: 24 weeks
Dietary Intake
Short Healthy Eating Index
Time frame: 24 weeks
Plan to share: Yes
Supporting information: Analytic code
This study is completed, as verified in Dec 2025. You cannot join it, but the record below documents what was studied.
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University of Alabama at Birmingham →