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CompletedNCT05432557Updated Dec 19, 2024

External Oblique Intercostal Plane Block Versus Subcostal Transversus Abdominis Plane Block in Supra-umbilical Surgical Incisions

An interventional study of external oblique intercostal plain block (EOIP) and subcostal transversus abdominis plane block (SCTAP) in Pain, Postoperative, sponsored by Benha University. Completed at 1 site in Egypt. Open to participants aged 20 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-12-19.

Sponsored by Benha University · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
60
Allocation
Randomized
Ages
20 Years to 60 Years
Sex
All
01

Study summary

Various newer techniques have been proposed to enhance analgesia in upper abdominal region. The subcostal transverse abdominis plane (SCTAP) block is the deposition of local anesthetic in the transverse abdominis plane inferior and parallel to the costal margin. There is a growing consensus that the SCTAP block provides better analgesia for upper abdominal incisions than the traditional transverse abdominis plane block.

The External oblique intercostal plane (EOIP) block is a novel technique reported by Hamilton et al. performed EOPB by administering LA superior or deep of the external oblique muscle from the sixth intercostal space leading to the blockage of thoracoabdominal nerves at T6-T10. It has several attractive aspects such as easy sono-anatomy ribs one strip of muscle so easy to demonstrate even in obese patients, there is a bony backstop, easy expandable fascial plane that can accommodate a catheter and it is shallow block with no big vessels nearby.

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Conditions studied

  • Pain, Postoperative
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In context

Pain, Postoperative

5,093 studies on the registry are indexed under Pain, Postoperative; 1,140 are open to participants now.

This study's enrollment of 60 is below the median of 75 across 4,344 interventional studies indexed under Pain, Postoperative.

Browse Pain, Postoperative studies →

Lead sponsor

Benha University is the lead sponsor of 356 studies on the registry; 68 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 60 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  1. American Society of Anesthesiologists (ASA) physical status grade I -II,
  2. Scheduled to undergo elective supra-umbilical surgeries under GA (epigastric herniotomy- gastrectomy- open cholecystectomy- nephrectomy).

Exclusion criteria

Exclusion Criteria:

  1. Allergy to local anesthetics,
  2. Infection at the site of injection,
  3. Coagulopathy,
  4. Chronic pain syndromes,
  5. Prolonged opioid medication,
  6. Patients who received any analgesic 24 h before surgery.
  7. Chronic liver disease, chronic renal disease, and cognitive impairment.
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Outcomes assessor)
Enrollment
60 participants (actual)

Study arms

  • Experimental
    Group E

    patients will receive ultrasound guided external oblique intercostal plain block.

    Procedure: external oblique intercostal plain block (EOIP)

  • Experimental
    Group T

    patients will receive ultrasound guided subcostal transversus abdominis plane block.

    Procedure: subcostal transversus abdominis plane block (SCTAP)

  • Placebo comparator
    Group C

    patients won't receive LA injection

    Other: control group

Interventions

  • Procedureexternal oblique intercostal plain block (EOIP)

    A high-frequency linear ultrasound probe will be placed in a longitudinal parasagittal orientation at the sixth intercostal space in the anterior midaxillary line. A 21G 10 cm needle will be inserted using an in plane approach. The tip of the needle will be placed into the fascial plane on the deep aspect of the external oblique muscle. A volume of 20 mL of LA mixture (10 mL of bupivacaine 0.5%, 5 mL of lidocaine 2% and 5 mL of normal saline to make a mixture totaling 20 ml.) will be injected.

  • Proceduresubcostal transversus abdominis plane block (SCTAP)

    The US probe will be placed immediately below the costal margin on oblique plane toward the lateral close to midline to identify the rectus abdominis muscle. The transversus abdominis muscle will be identified lying posterior to the rectus muscle. An 8cm 22-gauge block needle will be inserted using an in- plane approach. transversus abdominis plane will be accessed by placing the needle adjacent to costal margin but medial to linea semilunaris. The needle will be advanced slowly in-plane to promote hydrodissection along the oblique subcostal line. A volume of 20 mL of LA mixture (10 mL of bupivacaine 0.5%, 5 mL of lidocaine 2% and 5 mL of normal saline to make a mixture totaling 20 ml.) will be injected.

  • Othercontrol group

    No LA injection

06

What researchers measure

Primary outcomes

  1. amount of postoperative morphine consumed

    Time frame: 24 hours postoperatively

  2. First postoperative analgesics request

    Time frame: 24 hours postoperatively

Secondary outcomes

  1. Postoperative pain score

    pain evaluated by VAS (visual analogue score).

    Time frame: at 1, 2,4 , 8, 16 and 24 hours postoperatively

  2. Incidence of Postoperative nausea & vomiting (PONV)

    Number of patients developing PONV

    Time frame: 24 hours postoperatively

  3. incidence of complications related to the block

    agitation, dizziness, tinnitus, tremors, and numbness.

    Time frame: 24 hours postoperatively

07

Study locations

1 site
  • Samar Rafik Amin
    Banhā, Qalubia 13511, Egypt
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 19, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT05432557
Lead sponsor
Benha University
Responsible party
Samar Rafik Mohamed Amin (lecturer of anesthesia and surgical ICU, Benha University) — Principal investigator
First posted
Jun 27, 2022
Start date
Jun 20, 2022
Primary completion
Dec 10, 2022
Completion
Apr 20, 2023
Last update
Dec 19, 2024

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Dec 2024. You cannot join it, but the record below documents what was studied.

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