An interventional study of Cardiac magnetic resonance imaging to study coronary microvascular dysfunction in Myocardial Infarction with Nonobstructive Coronary Arteries, sponsored by Karolinska Institutet. Recruiting at 1 site in Sweden. Open to participants aged 35 Years to 79 Years. Per ClinicalTrials.gov, last updated 2025-03-10.
Sponsored by Karolinska Institutet · Not applicable, Interventional, and Diagnostic
The present pilot study will investigate the prevalence of CMD in an unselected cohort of patients with the working diagnosis MINOCA and to study if the diagnostic yield can be improved by adding adenosine to the CMR investigation. Patient will be their own controls.
Exclusion Criteria:
Patients will be their own controls
Diagnostic Test: Cardiac magnetic resonance imaging to study coronary microvascular dysfunction
Myocardial perfusion mapping will be investigated after administration of adenosine
Diagnostic yield
To increase the diagnostic yield of CMR imaging in MINOCA as a working diagnosis
Time frame: Through investigation completion, usually 2 hours
Prevalence of CMD in MINOCA
To determine the proportion of patients with the working diagnosis of MINOCA who have CMD.
Time frame: Through investigation completion, usually 2 hours
Prevalence of CMD in different final MINOCA diagnoses
To study the proportions of CMD in patients with a CMR imaging diagnosis of myocardial infarction, Takotsubo, respectively myocarditis and compare them with the results from a healthy control group
Time frame: Through investigation completion, usually 2 hours
Angina pectoris
To investigate the occurrence of angina pectoris before inclusion and after 3 months and relate it to CMD
Time frame: 3 Months
Plan to share: No
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Karolinska Institutet