An interventional study of LowSalt4Life Application and Just-In-time Adaptive Intervention (JITAI) in Hypertension and Blood Pressure, sponsored by University of Michigan. Completed at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-11-18.
Sponsored by University of Michigan · Not applicable, Interventional, and Prevention
This research is being done to learn if a smartphone app with and without a just in time adaptive intervention (JITAI) can help patients with hypertension manage their sodium intake and improve their blood pressure.
The primary and secondary outcomes will be determined in months 1 \& 2. Participants will continue for another 4 months and during that time data for exploratory measures will be collected.
During the first 2 months of the study, a micro-randomized trial (MRT) will be performed within the App+JITAI group (N=200). This MRT is designed to learn which push notification messages effectively prompt the user to interact with the appropriate content within the mobile application.
6,689 studies on the registry are indexed under Hypertension; 965 are open to participants now.
This study's enrollment of 410 is above the median of 90 across 4,995 interventional studies indexed under Hypertension.
Browse Hypertension studies →University of Michigan is the lead sponsor of 1,475 studies on the registry; 196 are open to participants now.
Of its 162 completed or terminated interventional studies of FDA-regulated products, 128 (79%) have results posted.
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Exclusion Criteria:
Behavioral: LowSalt4Life Application
Behavioral: LowSalt4Life Application · Behavioral: Just-In-time Adaptive Intervention (JITAI)
LowSalt4Life is a dietary sodium intervention mobile application that promotes lower sodium intake.
LowSalt4Life is a dietary sodium application with a just-in-time adaptive intervention (JITAI) component enabled.
Change in systolic blood pressure (SBP)
SBP measured by a wireless home blood pressure monitor
Time frame: Baseline, 2 months
Change in weight over 2 months
Weight measured using wireless scale
Time frame: Baseline, 2 months
Change in estimated sodium intake
As measured by the Block 2014 Food Frequency Questionnaire
Time frame: Baseline, 2 months
Change in dietary nutrient intake
As measured by the Block 2014 Food Frequency Questionnaire
Time frame: Baseline, 2 months
Changes in blood pressure (BP) medications
As measured by the electronic health record
Time frame: Baseline, 2 months
Percent of participants at a goal blood pressure (BP)
Goal BPs are based on the American Heart Association blood pressure guidelines.
Time frame: 2 months
Documents are hosted by the registry — open the source record to download them.
Plan to share: Yes — The aim is to prepare data for deposit into the National Heart, Lung, and Blood Institute (NHLBI) supported Biologic Specimen and Data Repositories Information Coordinating Center (BioLINCC).Unique research data be made available to the scientific community after the conclusion of a study. The de-identified analytic data will be prepared as SAS transport files or ASCII comma-delimited files with accompanying codebooks that describe the data and data structure. The redaction will employ best practices and will be consistent with National Heart, Lung, and Blood Institute data sharing policies.
Supporting information: Study protocol, Icf
This study is completed, as verified in Nov 2025. You cannot join it, but the record below documents what was studied.
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University of Michigan