An observational study in Pims-Ts, sponsored by Brno University Hospital. Completed at 1 site in Czechia. Open to participants aged Up to 19 Years. Per ClinicalTrials.gov, last updated 2023-02-14.
Sponsored by Brno University Hospital · Observational
Pediatric Multisystem Inflammatory Syndrome Temporally associated with SARS-CoV-2, (PMIS-TS) represents the new unit, partially imitating the previously described Kawasaki disease. Due to variable and frequently incomplete clinical presentation together with variable disease severity, the real incidence in pediatric population remains unclear. Currently, PIMS-TS is defined by persistent fever, elevation of inflammatory markers, organ dysfunction (cardiac, central nervous system, respiratory, coagulation, renal, gastrointestinal), skin lesions (exanthematous), and absence of other possible etiology.
During the world COVID-19 pandemic (2020-2022), pediatric patients with PIMS-TS represented a significant part of pediatric intensive care unit (PICU) load. The initial clinical presentation of patients with PIMS-TS could vary significantly, and also due to progressively evolving recommendations, the diagnostic a therapy could vary regionally and over the time too. The aim of this retrospective cohort trial was to describe the initial clinical presentation, diagnostics, therapy and clinical outcome of pediatric patients admitted during 2020-2022 to the one of the 3 university hospital PICUs.
Brno University Hospital is the lead sponsor of 91 studies on the registry; 22 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Pediatric patients with PIMS-TS admitted to PICU
Exclusion Criteria:
Pediatric patients with PIMS-TS admitted to the PICU in selected time period
Other: PIMS-TS diagnostic a treatment
PIMS-TS diagnostic a treatment
Initial clinical presentation
Vital signs
Time frame: During the first 24 hours after PICU admission
Initial laboratory results
Time frame: During the first 24 hours after PICU admission
PIMS-TS treatment
PIMS-TS treatment specification
Time frame: During the first month after PICU admission
PIMS-TS outcome
clinical and cardiology outcome after 1 month
Time frame: after one month from hospital discharge
Plan to share: Undecided
No publications or documents are linked to this record.
This study is completed, as verified in Feb 2023. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Brno University Hospital