An observational study in Acute Ischemic Stroke, sponsored by Xuanwu Hospital, Beijing. Status unknown at 1 site in China. Open to participants aged 18 Years to 75 Years. Per ClinicalTrials.gov, last updated 2022-05-17.
Sponsored by Xuanwu Hospital, Beijing · Observational
The investigators evaluate the activation and connectivity of patients' motor regions in the acute phase of ischemic stroke by fNIRS.
This study aims to analyze the progress of brain recovery from upper-limb deficit due to acute ischemic stroke, using Functional Near-infrared Spectroscopy(fNIRS) as the main neural imaging method. Fifty patients having experienced a stroke onset within seven days will be recruited from the emergency room. The fNIRS signals will be recorded bilaterally over the contralateral sensorimotor cortex, the premotor area, the supplementary motor area, the primary motor cortex for 14 days after being diagnosed. Then compute activation and connectivity of the regions. The motor function data measured by the assessment scales, as well as the behavioral record during the fNIRS motor tasks will be collected as well.
7,286 studies on the registry are indexed under Stroke; 2,007 are open to participants now.
This study's planned enrollment of 50 is below the median of 160 across 1,692 observational studies indexed under Stroke.
Browse Stroke studies →Xuanwu Hospital, Beijing is the lead sponsor of 346 studies on the registry; 217 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Patients with acute ischemic stroke with upper limb motor dysfunction diagnosed and treated by the Xuanwu Hospital Capital Medical University.
Exclusion Criteria:
fNIRS characteristics of upper limb movement
The changes in brain oxygen levels are collected in two wavelengths, including 845 and 763 nanometers using a 44 channeled fNIRS machine. The data is used to determine the position of the activated area of the brain and functional connectivity during the movement. The locations of fNIRS channels on the skull of individuals are determined due to the observations on the cortical regions of interest (ROIs), namely the contralateral sensorimotor cortex (SMC), the contralateral premotor cortex (PMC) and primary motor cortex (M1), etc.
Time frame: 0-14 day
Assessment of upper limb function
Recording the quality and frequency of fNIRS motion tasks including grip and reach-out movements.
Time frame: 0-14 day
Assessment of upper limb function
Evaluating the motor function by Action Research Arm Test.
Time frame: 0-14 day
Assessment of upper limb function
Evaluating the motor function by Fugl-meyer assessment.
Time frame: 0-14 day
This study is status unknown, as verified in Dec 2021. You cannot join it, but the record below documents what was studied.
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Xuanwu Hospital, Beijing