An interventional study of Resonance breathing and Low demand cognitive task in Binge Drinking, sponsored by Rutgers, The State University of New Jersey. Completed at 1 site in United States. Open to participants aged 18 Years to 35 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-04-20.
Sponsored by Rutgers, The State University of New Jersey · Not applicable, Interventional, and Basic science
Conscious attempts to regulate alcohol use are often undermined by automatic attention and arousal processes activated by alcohol cues, as well as by diminished ability to inhibit in-the-moment behaviors. The current study will examine whether a brief behavioral intervention of slow breathing paced at a resonance frequency of the cardiovascular system can interrupt automatic alcohol cue reactivity and enhance cognitive control in binge drinkers. Results from the proposed study may provide new prevention and intervention targets to interrupt unhealthy drinking behaviors.
71 studies on the registry are indexed under Binge Drinking; 20 are open to participants now.
This study's enrollment of 100 is below the median of 120 across 64 interventional studies indexed under Binge Drinking.
Browse Binge Drinking studies →Rutgers, The State University of New Jersey is the lead sponsor of 506 studies on the registry; 131 are open to participants now.
Of its 39 completed or terminated interventional studies of FDA-regulated products, 31 (79%) have results posted.
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Active resonance breathing task consisting of synchronizing breathing with a visual pacer (E-Z Air, Thought Technology, Ltd., Plattsburgh, NY) that moves up (inhale) and down (exhale) at the rate of 0.1 Hz (6 breaths per min)
Behavioral: Resonance breathing
A low-demand cognitive "vanilla" task wherein different colored rectangles are presented for 10 sec each, and participants are instructed to silently count the number of blue rectangles
Behavioral: Low demand cognitive task
Participants will synchronize their breathing with a visual pacer (E-Z Air, Thought Technology, Ltd., Plattsburgh, NY) that moves up (inhale) and down (exhale) at the rate of 0.1 Hz (6 breaths per min)
Different colored rectangles are presented for 10 sec each, and participants are instructed to silently count the number of blue rectangles
N2 ERP amplitude (in microvolts) elicited from an Alcohol Cued Go/No-Go task
The N2 component (in microvolts) of the event-related potential occurring 250-350 ms after stimulus presentation at frontal and central electrode sites during an Alcohol Cued Go/No-Go task following a 5-minute course of resonance breathing compared to a low-demand control task
Time frame: Immediate; Difference between the active resonance breathing compared to the low demand cognitive task occurring one week apart
N2pc ERP amplitude (in microvolts) elicited from a visual dot probe detection task
The N2pc component of the event-related potential occurring 200-275 ms after stimulus presentation at parietal and occipital electrode sites (ipsilateral minus contralateral hemisphere activity) during a modified visual dot probe detection task following a 5-minute course of resonance breathing compared to a low-demand control task
Time frame: Immediate; Difference between the active resonance breathing compared to the low demand cognitive task occurring one week apart
P3b ERP amplitude (in microvolts) elicited from a picture-viewing task
The P3b component of the event-related potential occurring 300-600 ms after stimulus presentation at central and parietal electrode sites during a picture viewing task following a 5-minute course of resonance breathing compared to a low-demand control task
Time frame: Immediate; Difference between the active resonance breathing compared to the low demand cognitive task occurring one week apart
N2 ERP latency (in milliseconds) elicited from an Alcohol Cued Go/No-Go task
The latency of the N2 component of the event-related potential from frontal and central electrode sites during a picture viewing task following a 5-minute course of resonance breathing compared to a low-demand control task. Latency will be determined using 50% area latency from a difference wave between task conditions
Time frame: Immediate; Difference between the active resonance breathing compared to the low demand cognitive task occurring one week apart
N2pc ERP latency (in milliseconds) elicited from a visual dot probe detection task
The latency of the N2pc component of the event-related potential from parietal and occipital electrode sites during a visual dot probe detection task following a 5-minute course of resonance breathing compared to a low-demand control task. Latency will be determined using 50% area latency from a difference wave between task conditions
Time frame: Immediate; Difference between the active resonance breathing compared to the low demand cognitive task occurring one week apart
P3b ERP latency (in milliseconds) elicited from a picture-viewing task
The latency of the P3b component of the event-related potential from central and parietal electrode sites during a picture viewing task following a 5-minute course of resonance breathing compared to a low-demand control task. Latency will be determined using 50% area latency from a difference wave between task conditions
Time frame: Immediate; Difference between the active resonance breathing compared to the low demand cognitive task occurring one week apart
Task accuracy from the behavioral response during the Alcohol Cued Go/No-Go task
Task accuracy as a percentage of correct behavioral responses to the task during the Alcohol Cued Go/No-Go ERP task following a 5-minute course of resonance breathing compared to a low-demand control task
Time frame: Immediate; Difference between the active resonance breathing compared to the low demand cognitive task occurring one week apart
Reaction time from the behavioral response during the Alcohol Cued Go/No-Go task
Reaction time for the correct behavioral responses to the task measured in milliseconds during the Alcohol Cued Go/No-Go ERP task following a 5-minute course of resonance breathing compared to a low-demand control task
Time frame: Immediate; Difference between the active resonance breathing compared to the low demand cognitive task occurring one week apart
Task accuracy from the behavioral response during the visual dot probe detection task
Task accuracy as a percentage of correct behavioral responses to the task during the visual dot probe detection task following a 5-minute course of resonance breathing compared to a low-demand control task
Time frame: Immediate; Difference between the active resonance breathing compared to the low demand cognitive task occurring one week apart
Reaction time from the behavioral response during the visual dot probe detection task
Reaction time for the correct behavioral responses to the task measured in milliseconds during the visual dot probe ERP task following a 5-minute course of resonance breathing compared to a low-demand control task
Time frame: Immediate; Difference between the active resonance breathing compared to the low demand cognitive task occurring one week apart
PDFs hosted by the registry, ClinicalTrials.gov.
Plan to share: Yes — We plan to share data via the NIAAA Data Archive (NIAAADA) repository within the larger National Institute of Mental Health (NIMH) Data Archive (NDA). Data generated by the proposed project include the following information on participants (male and female) aged 18-35 years: Surveys: Basic Demographics (Age, Sex, Race/Ethnicity, Height/Weight) Current Alcohol and Substance Use Alcohol Use Questionnaire (AUQ), Penn Alcohol Craving Scale (PACS), and Alcohol Sensitivity Questionnaire Electrophysiological Data: N2pc, P3b, and N2 components of the human event-related brain potential (ERP) Collected during three cognitive tasks of cue reactivity (2) and inhibitory control (1)
Supporting information: Study protocol, Statistical analysis plan, Informed consent form
Time frame: At the conclusion of data collection and no later than 24 months after the NIH award end date or 6 months post-publication of the final data set (whichever date occurs first). There is no restriction for how long the data will be available.
This study is completed, as verified in Apr 2026. You cannot join it, but the record below documents what was studied.
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