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CompletedNCT05365373Updated May 9, 2022

The Effect of Treatment Zone Decentration on Axial Length Elongation After Orthokeratology

An observational study in Myopia and Orthokeratology, sponsored by Tianjin Eye Hospital. Completed at 1 site in China. Open to participants aged 8 Years to 15 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-05-09.

Sponsored by Tianjin Eye Hospital · Observational

Study type
Observational
Model
Other
Time perspective
Retrospective
Enrollment
251
Ages
8 Years to 15 Years
Sex
All
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Study summary

Orthokeratology lens is an effective method for myopia control. This study analyzed the effects of treatment zone decentration on axial length elongation in adolescents with orthokeratology lens.

Read the detailed description

Orthokeratology lens is an effective method for myopia control. This study aimed to investigate the effects of treatment zone decentration on axial length elongation in adolescents with orthokeratology lens in 1 year. Other factors that may affect axial growth were also analyzed.

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Conditions studied

  • Myopia
  • Orthokeratology

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Keywords

  • Myopia
  • Orthokeratology
  • Axial length
  • Decentration
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In context

Myopia

984 studies on the registry are indexed under Myopia; 210 are open to participants now.

This study's enrollment of 251 is above the median of 150 across 173 observational studies indexed under Myopia.

Browse Myopia studies →

Lead sponsor

Tianjin Eye Hospital is the lead sponsor of 49 studies on the registry; 15 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
8 Years to 15 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Myopia children with orthokeratology lens and complete follow-up.

Inclusion criteria

  • age from 8 to 15years
  • spherical equivalent(SE) was range from -1.00D to -5.00D
  • conform to the standard of wearing orthokeratology lens

Exclusion criteria

Exclusion Criteria:

  • ocular diseases and systemic diseases
  • stop wearing for ≥7 days for any reason during the follow-up period
  • keratoconjunctival complications, glare, diplopia, or any other symptoms during follow-up
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Study design

Observational model
Other
Time perspective
Retrospective
Enrollment
251 participants (actual)
Patient registry
No
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What researchers measure

Primary outcomes

  1. The change of axial length

    The axial length was measured by IOL-Master 500, its expressed in mm

    Time frame: The change of baseline、6 months and 12months

Secondary outcomes

  1. the decentration magnitudes of the treatment zone

    The value of decentration magnitudes was obtained and calculated from a corneal topography

    Time frame: up to 1 year

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Study locations

1 site
  • Tianjin Eye Hospital
    Tianjin, Tianjin, China
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References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 9, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT05365373
Lead sponsor
Tianjin Eye Hospital
Responsible party
Sponsor
First posted
May 9, 2022
Start date
Jan 1, 2018
Primary completion
Dec 31, 2019
Completion
Dec 31, 2019
Last update
May 9, 2022

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in May 2022. You cannot join it, but the record below documents what was studied.

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