An observational study in Amelogenesis Imperfecta and Dental Age Estimation, sponsored by Istanbul University. Completed at 1 site in Turkey (Türkiye). Open to participants aged 5 Years to 13 Years. Per ClinicalTrials.gov, last updated 2024-08-22.
Sponsored by Istanbul University · Observational
The aim of this study is to investigate whether there is a significant difference in dental age between children with amelogenesis imperfecta (AI) and healthy controls using Cameriere European formula and London Atlas. If there is a significant difference in dental age between children with AI and healthy controls, it is aimed to create a new formula.
One of the developmental enamel defects, amelogenesis imperfecta (AI), is also known as enamel hypoplasia/hypomineralization. It is a rare inherited disease that affects the enamel structure, amount and component in primary and permanent teeth, and it has been reported to be accompanied by some dental anomalies and nephrocalcinosis. Dental anomalies and nephrocalcinosis can affect tooth development, and there are limited studies examining tooth development in these individuals.Dental age is widely evaluated by pedodontists, forensic dentists and orthodontists. While a delay in tooth development may be associated with growth retardation and learning difficulties, dental age determination can also be used for forensic age determination for children whose birth information is uncertain. A clear assessment of maturation in children with continued growth is important in establishing a dental treatment plan.
Dental age is widely evaluated by pedodontists, forensic dentists and orthodontists. While a delay in tooth development may be associated with growth retardation and learning difficulties, dental age determination can also be used for forensic age determination for children whose birth information is uncertain. A clear assessment of maturation in children with continued growth is important in establishing a dental treatment plan.
There are two basic approaches to dental age determination in children:
In many methods, the developmental stages of different numbers of permanent teeth are used.
One of the most widely used methods of dental age determination recently is the European formula of Cameriere et al., which is calculated based on open apex. It has been reported that this method has been tested on different population groups, and the results are accurate and reliable.
An atlas method was proposed by a group of London researchers in 2010. The Atlas shows all the teeth array images of certain age groups as a schematic series. Age determination is made by deciding which reference image matches the individual's panoramic radiography image more.
Istanbul University is the lead sponsor of 507 studies on the registry; 80 are open to participants now.
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This study was conducted on gender-age matched healthy control group of children aged 5-13 years, who applied to Istanbul University Faculty of Dentistry, Department of Pedodontics, had an AI record in their anamnesis, had panoramic radiographs in the archive of the Department of Oral and Maxillofacial Radiology, Istanbul University Faculty of Dentistry.
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Exclusion Criteria:
Diagnostic Test: Cameriere method · Diagnostic Test: London Atlas method
Diagnostic Test: Cameriere method · Diagnostic Test: London Atlas method
Cameriere et al. designed a quantitative approach through a formula based on sex and the ratio between length and apex opening measurements of each lower left tooth.
The London Atlas requires the user to assess the tooth development and eruption and then match it to one of the 31 pictures of age categories.
Correlation coefficient of London Atlas method.
Dental age of children with AI and healthy controls assessed by the correlation coefficient.
Time frame: day 1
Correlation coefficient of Cameriere European formula.
Dental age of children with AI and healthy controls assessed by the correlation coefficient.
Time frame: day 1
Dental age estimation in children with AI
Dental age estimation in Turkish children
Time frame: day 1
Plan to share: No
No publications or documents are linked to this record.
Ran from Mar 2022 to primary completion in Apr 2024, 25 months.
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This study is completed, as verified in Nov 2023. You cannot join it, but the record below documents what was studied.
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Amelogenesis Imperfecta