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SuspendedNCT05312996Updated May 3, 2023

Autonomic Nervous System Function - Hypertension

An interventional study of Heart Rate Variability and Galvanic Skin Response (Biopac) in Hypertension, sponsored by Life University. Suspended at 1 site in United States. Open to participants aged 18 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2023-05-03.

Sponsored by Life University · Not applicable, Interventional, and Basic science

Why this study was suspended
Prioritizing other studies

From the registry’s dates

  • Registered 5 months after the study started (first participant enrolled Oct 2021, registered Mar 2022).
Phase
Not applicable
Study type
Interventional
Enrollment
30
Allocation
Non-randomized
Ages
18 Years to 65 Years
Sex
All
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Study summary

The Life University Center for Chiropractic Research is conducting a research study to better understand the physiological differences, in terms of Autonomic nervous system function, between individuals with Hypertension and control individuals with out hypertension. Data will be gathered using Heart Rate Variability (HRV), and Galvanic Skin Response (GSR). A series of tests will be conducted to elicit Autonomic Nervous system responses. These tests include Cold Face Test (mammalian dive reflex), Cold Pressor test, Sit to stand, and the Valsalva maneuver.

Read the detailed description

The objective of the study is to ascertain the level of autonomic health in persons with hypertension versus a healthy population. Further, via the implemented protocol, the study will attempt to develop a sequence of autonomic nervous system tests to be used in future studies and clinical settings

02

Conditions studied

  • Hypertension

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03

In context

Hypertension

6,689 studies on the registry are indexed under Hypertension; 965 are open to participants now.

This study's planned enrollment of 30 is below the median of 90 across 4,995 interventional studies indexed under Hypertension.

Browse Hypertension studies →

Lead sponsor

Life University is the lead sponsor of 29 studies on the registry; 4 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Eligibility criteria

Participants will be included in the hypertension group if they present with the following:

  • Hypertension, defined as:
  • Self-reported or previously diagnosed with elevated resting state blood pressure (120-129 systolic and less than 80 mmHg diastolic) or stage 1 hypertension with a blood pressure of Systolic between 130- and 139-mm Hg with a diastolic of 80-89 mmHg.
  • Or medically diagnosed and managed stage 2 hypertension with blood pressure of Systolic between 140- and 159-mm Hg or diastolic 90 and 99 mm
  • between the ages of 18-65
  • Able to wear a monitor on their right wrist.
  • Able to wear a pulse oximeter on their left hand.

Participants will be included in the healthy group if they present with the following:

  • between the ages of 18-65
  • Able to wear a monitor on their right wrist.
  • Able to wear a pulse oximeter on their left hand.
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Study design

Phase
Not applicable
Primary purpose
Basic science
Allocation
Non-randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
30 participants (estimated)

Study arms

  • Experimental
    Hypertension

    Hypertension test group.

    Other: Heart Rate Variability · Other: Galvanic Skin Response (Biopac)

  • Other
    Active Comparator

    Non Hypertension compare group.

    Other: Heart Rate Variability · Other: Galvanic Skin Response (Biopac)

Interventions

  • OtherHeart Rate Variability

    Caretaker Heart Rate Variability ECG wrist monitor and chest patch.

  • OtherGalvanic Skin Response (Biopac)

    Galvanic Skin Response- measuring autonomic response-via perspiration

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What researchers measure

Primary outcomes

  1. Heart Rate Varability

    Caretaker Heart Rate Variability (HRV) Electrocardiogram (ECG) wrist monitor and chest patch.

    Time frame: Through study completion, an average of 1 year

  2. Galvanic Skin Response

    Galvanic Skin Response- measuring autonomic response-via perspiration

    Time frame: Through study completion, an average of 1 year

07

Study locations

1 site
  • Dr. Sid E. Williams Center for Chiropractic Research
    Atlanta, Georgia 30308, United States
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 3, 2023, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT05312996
Lead sponsor
Life University
Responsible party
Sponsor
First posted
Apr 6, 2022
Start date
Oct 1, 2021
Primary completion
Oct 26, 2023 (estimated)
Completion
Oct 26, 2023 (estimated)
Last update
May 3, 2023

Study contacts

Stephanie Sullivan, DC, PhD
study director · Life Univeristy

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is suspended, as verified in May 2023. You cannot join it, but the record below documents what was studied.

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