An interventional study of Philips SmartSleep Acoustic Stimulation Device and Sham (no Acoustic Stimulation) in Sleep Deprivation, Sleep Restriction and Acoustic Stimulation, sponsored by Walter Reed Army Institute of Research (WRAIR). Recruiting at 1 site in United States. Open to participants aged 18 Years to 39 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-04-23.
Sponsored by Walter Reed Army Institute of Research (WRAIR) · Not applicable, Interventional, and Treatment
The purpose of this study is to determine if brief sounds or tones presented within a restricted period of recovery sleep after a period of sleep deprivation will enhance restorative properties and improve performance during a subsequent period of wakefulness.
Exclusion Criteria:
Following 40 hours of deprivation participants will sleep for approximately a four hour recovery sleep period and receive acoustic stimulation via the Philips SmartSleep during slow-wave sleep. They will then sleep for second night of four hour recovery sleep and receive acoustic stimulation via the Philips Smart Sleep device during slow-wave sleep again.
Device: Philips SmartSleep Acoustic Stimulation Device
Following 40 hours of deprivation participants will sleep for approximately a four hour recovery sleep period and receive Sham (no acoustic stimulation) via the Philips SmartSleep during slow-wave sleep. They will then sleep for second night of four hour recovery sleep and receive Sham (no acoustic stimulation) via the Philips Smart Sleep device during slow-wave sleep again.
Device: Sham (no Acoustic Stimulation)
Prior to bedtime on the first two recovery nights, a Philips SmartSleep device will be applied to the head of each subject. Subjects will receive acoustic stimulation during the four hours of sleep.
Prior to bedtime on the first two recovery nights, a Philips SmartSleep device will be applied to the head of each subject. Subjects will receive Sham (no acoustic stimulation) during the four hours of sleep.
Measure the effects of sleep deprivation/sleep restriction on performance using the Psychomotor Vigilance Task (PVT)
Performed at approximately 75 minutes intervals throughout the sleep deprivation and recovery days
Time frame: 8 days
Measure simple arithmetic processing using the Mathematical Processing Subtest of the Automated Neuropsychological Assessment Metrics 4 (ANAM4)
Computer based series of mathematical calculations
Time frame: 5 days
Measure current mood states using the Mood Analogue Scale (MAS)
Computer based self adjective checklist of measure mood states
Time frame: 5 days
Measure latency to sleep using the Maintenance of Wakefulness Test (MWT)
Subjects will be escorted to their individual darkened, sound-attenuated bedrooms and allowed to lie down on their beds. They will be instructed to close their eyes and try to remain awake. Polysomnography will be monitored online.
Time frame: 5 days
Measure alertness using the Karolinska Sleepiness Scale (KSS)
Computer based self rated level of sleepiness
Time frame: 5 days
Measure various aspects of mood using the Walter Reed Army Institute of Research (WRAIR) Mood Battery
Computer based battery testing various aspects of mood
Time frame: 5 days
Measure various aspects of Sleep and Wakefulness using Polysomnographic measurements with video
Sleep will be measured during the night using polysomnography
Time frame: 5 days
Measure various aspects of Sleep and Wakefulness using Actigraphy
A watch-like device called an actigraph will measure movement to determine wake and sleep
Time frame: 22 days
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Walter Reed Army Institute of Research (WRAIR)