An observational study in Periodontal Diseases, sponsored by Cairo University. Completed at 1 site in Egypt. Open to participants aged 18 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2023-11-24.
Sponsored by Cairo University · Observational
The aim of this study is to assess the levels of galectin-3 in the GCF and saliva in patient with gingivitis and patient with stage III periodontitis.
The aim of this study is to assess the levels of galectin-3 in the GCF and saliva in patient with gingivitis and patient with stage III periodontitis.
This study will be conducted in the Oral Medicine and Periodontology department, Faculty of Dentistry- Cairo University, Egypt.
Patients will be selected from the outpatient clinic of the department of Oral Medicine and Periodontology, Faculty of Dentistry-Cairo University.
830 studies on the registry are indexed under Periodontal Diseases; 188 are open to participants now.
This study's enrollment of 66 is below the median of 100 across 291 observational studies indexed under Periodontal Diseases.
Browse Periodontal Diseases studies →Cairo University is the lead sponsor of 4,780 studies on the registry; 1,427 are open to participants now.
Of its 36 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.
Counted across the registry records on this site, refreshed daily.
Dental patients will be recruited in a consecutive manner from the clinic of the department of Oral Medicine and Periodontology, Faculty of Dentistry - Cairo University. Medical history and dental history will be taken; thorough oral examination will be done. The aim of the study will be explained to the patient and the patient's acceptance to participate in the survey will be received. Nonrespondent patients or patients refusing to participate will be reported with the cause of their refusal. Conventional oral and periodontal examination will be held on a dental unit using the light of the unit, mirror and probe
Exclusion Criteria:
Full-mouth clinical periodontal measurements recorded, saliva and GCF obtained
Diagnostic Test: GCF obtaining · Diagnostic Test: saliva obtaining
Full-mouth clinical periodontal measurements recorded, saliva and GCF obtained
Diagnostic Test: GCF obtaining · Diagnostic Test: saliva obtaining
Full-mouth clinical periodontal measurements recorded, saliva and GCF obtained
Diagnostic Test: GCF obtaining · Diagnostic Test: saliva obtaining
GCF sample collection by Enzyme-Linked Immunosorbent Assay (ELISA)
Saliva sample collection by Enzyme-Linked Immunosorbent Assay (ELISA)
galectin-3 in GCF
The total amount of Galectin-3 in GCF
Time frame: 24 hours after taking the clinical measurements at the first visit
galectin-3 in saliva.
The total amount of Galectin-3 in saliva
Time frame: 24 hours after taking the clinical measurements at the first visit
Pocket depth
in mm
Time frame: 24 hours before taking GCF and salivary samples
Clinical attachment level
in mm
Time frame: 24 hours before taking GCF and salivary samples
Bleeding on Probing
By gently probing the orifice of the gingival crevice, the periodontal probe will be inserted 1 to2 mm into the gingival sulcus starting at one interproximal area and moving to the other. If bleeding occurs within 10 seconds a positive finding is recorded.
Time frame: 24 hours before taking GCF and salivary samples
Plaque Index
Scores: 0: No plaque 1. A film of plaque adhering to the free gingival margin and adjacent area of the tooth. The plaque may be seen insitu only after application of a disclosing solution or by using the probe on the tooth surface. 2. Moderate accumulation of soft deposit s within the gingival pocket, or the tooth and gingival margin, which can be seen with the naked eye. 3. Abundance of soft matter within the gingival pocket and/or on the tooth and gingival margin.
Time frame: 24 hours before taking GCF and salivary samples
This study is completed, as verified in Nov 2023. You cannot join it, but the record below documents what was studied.
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Cairo University