An Early Phase 1 interventional study of Dexmedetomidine Hydrochloride in Agitation, Emergence, sponsored by Sheikh Zayed Medical College. Status unknown. Open to participants aged 18 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-08-07.
Sponsored by Sheikh Zayed Medical College · Early Phase 1, Interventional, and Health services research
Comparison of effect of dexmedetomidine and midazolam in icu patients who put on mechanical ventilation and show agitation on weaning.Selection of better agent minimises the drug related side effects like respiratory depression but also helps in weaning for early extubation,give hemodynamic stability and reduce morbidity and mortality in icu..
788 studies on the registry are indexed under Emergence Delirium; 250 are open to participants now.
This study's planned enrollment of 66 is below the median of 120 across 491 interventional studies indexed under Emergence Delirium.
Browse Emergence Delirium studies →Sheikh Zayed Medical College is the lead sponsor of 27 studies on the registry; 8 are open to participants now.
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Exclusion Criteria:
- Patients who refuse to give consent, severely altered conscious level (GCS \< 8/15), traumatic injury causing hypoxemia e.g., severe head / chest / facial trauma or pneumothorax, severe pneumonia, arrhythmia, impaired hearing or blindness, severe hepatic or renal disease, on neuromuscular blocking agents, recent myocardial infarction, use of anti-psychotics, hypersensitivity to any of the drug under study.
Inj.Dexmedetomidine(precidex ) 200mcg/2ml Given to participants in infusion form for 24 hours
Drug: Dexmedetomidine Hydrochloride
Inj.midazolam 5mg/ml given to participants in infusion form for 24 hrs
Drug: Dexmedetomidine Hydrochloride
Inj dexmedetomidine and inj midazolam given to two groups of participants and effects of both drugs will be observed for 24 hrs
Also known as: Midazolam
Effective sedation in icu patients lead to successful 1weaning in icu patients
Assess patients by using ramsay sedation score (score 1 =awake upto score 6=no response)
Time frame: Upto 48 hrs
No study locations are listed for this record.
Plan to share: No
No publications or documents are linked to this record.
This study is status unknown, as verified in Aug 2024. You cannot join it, but the record below documents what was studied.
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Studies of the drug tested here: Dexmedetomidine
Sheikh Zayed Medical College