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CompletedNCT05240534Updated Oct 20, 2026Results posted

ElderTree Via a Voice Activated Device for Managing Chronic Health Conditions (NHLBI)

An interventional study of ET-Text (Laptop) and ET-Voice (Smart System) in Chronic Conditions, Multiple, sponsored by University of Wisconsin, Madison. Completed at 1 site in United States. Open to participants aged 60 Years and older. Per ClinicalTrials.gov, last updated 2026-10-20.

Sponsored by University of Wisconsin, Madison · Not applicable, Interventional, and Supportive care

Updated Oct 20, 2026Results postedStudy documents posted+1 moreGo to Updates ↓
Phase
Not applicable
Study type
Interventional
Enrollment
502
Allocation
Randomized
Ages
60 Years and older
Sex
All
01

Study summary

Multiple chronic conditions (MCCs) are costly and pervasive among older adults. MCCs account for 90% of Medicare spending, and 65% of Medicare beneficiaries have 3 or more chronic conditions; 23% have 5 or more. MCCs are often addressed in primary care, where time pressures force a focus on medication and lab results rather than self-management skills. Patients often struggle with treatment adherence and the emotional and physical burdens of self-management and health tracking. Chronic conditions reduce quality of life (QOL) and increase loneliness, which exacerbate those conditions.

The primary purpose of this study is to investigate whether a voice-based platform is better for delivering an electronic health intervention to older adults than a text/typing-based platform. Elder Tree (ET) is an evidence-based electronic health intervention that has been shown to improve quality of life, physical and socio-emotional health outcomes for older adults with multiple chronic conditions when delivered via a text/typing-based system. The current project would test whether such patients would benefit even more if ET were delivered via a voice-based system (vs. the text-based system) because they would use it more consistently. ET is an existing intervention providing tools, motivation, and support on a computer platform to help older adults manage their health.

02

Conditions studied

  • Chronic Conditions, Multiple

Keywords

  • Voice-activated "smart" technology
  • Older adults
03

In context

Multiple Chronic Conditions

89 studies on the registry are indexed under Multiple Chronic Conditions; 16 are open to participants now.

This study's enrollment of 502 is above the median of 128 across 71 interventional studies indexed under Multiple Chronic Conditions.

Browse Multiple Chronic Conditions studies →

Lead sponsor

University of Wisconsin, Madison is the lead sponsor of 1,188 studies on the registry; 181 are open to participants now.

Of its 157 completed or terminated interventional studies of FDA-regulated products, 118 (75%) have results posted.

Browse University of Wisconsin, Madison studies →

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
60 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Be ≥60 years old;
  • Have medical record diagnoses of at least 5 chronic conditions of which at least 3 must come from the following: hypertension, hyperlipidemia, obesity, prediabetes or diabetes, or depression;
  • Be willing to share medical record data about healthcare use (30-day hospital readmissions and ER, urgent care, primary care, and specialty care visits);
  • Allow researchers to share information with the patient's primary care provider

Exclusion criteria

Exclusion Criteria:

  • Require an interpreter
  • Report no current psychotic disorder that would prevent participation
  • Have no acute medical problem requiring immediate hospitalization
  • Not report impairments preventing use of a computer or tablet (e.g. blind, deaf)
05

Study design

Phase
Not applicable
Primary purpose
Supportive care
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Investigator, Outcomes assessor)
Enrollment
502 participants (actual)

Study arms

  • Placebo comparator
    Control group (ET-Text)

    Participants will receive ElderTree on a laptop.

    Behavioral: ET-Text (Laptop)

  • Experimental
    Experimental group (ET-Voice)

    Participants will receive ElderTree on a smart system.

    Behavioral: ET-Voice (Smart System)

Interventions

  • BehavioralET-Text (Laptop)

    ElderTree (ET) is based on the extensively tested Comprehensive Health Enhancement Support System (CHESS). ET is a "walled garden" free of ads, with design features based on older users' feedback as well as best-practice principles such as uncluttered screens and large type. Like all CHESS systems, ET uses computers to deliver key elements of successful interventions: long duration, ongoing outreach, prompts, monitoring, cognitive reframing, action planning, problem solving, self-tailoring, and peer support. ET-Text arm will access ET on Laptop.

    Also known as: ET-LT

  • BehavioralET-Voice (Smart System)

    ElderTree (ET) is based on the extensively tested Comprehensive Health Enhancement Support System (CHESS). ET is a "walled garden" free of ads, with design features based on older users' feedback as well as best-practice principles such as uncluttered screens and large type. Like all CHESS systems, ET uses computers to deliver key elements of successful interventions: long duration, ongoing outreach, prompts, monitoring, cognitive reframing, action planning, problem solving, self-tailoring, and peer support. ET-Voice arm will access ET on a smart speaker. Voice-activated devices can potentially be easy to use, even by those with limited dexterity or computer experience.

    Also known as: ET-SS

06

What researchers measure

Primary outcomes

  1. Physical Function as Assessed by the Patient-Reported Outcomes Measurement Information System (PROMIS) 29 v2.1

    Participant reported measure of overall health and level of physical disability. This is scored using the standardized T-scores with a general US population mean of 50 and a standard deviation of 10. Lower scores indicate worse outcomes.

    Time frame: Baseline, 6, 12, 18 months

  2. Pain Interference as Assessed by the PROMIS-29 v2.1

    Participant reported measure of pain interference. This is scored using the standardized T-scores with a general US population mean of 50 and a standard deviation of 10. Higher scores indicate worse outcomes.

    Time frame: Baseline, 6, 12, 18 months

  3. Pain Intensity as Assessed by the PROMIS-29 v2.1

    Participant reported measure of pain intensity, this is a single question, with a possible score of 0 to 10. Higher scores indicate worse outcomes.

    Time frame: Baseline, 6, 12, 18 months

  4. Fatigue as Assessed by the PROMIS-29 v2.1

    Participant reported measure of fatigue. This is scored using the standardized T-scores with a general US population mean of 50 and a standard deviation of 10. Higher scores indicate worse outcomes.

    Time frame: Baseline, 6, 12, 18 months

  5. Sleep as Assessed by the PROMIS-29 v2.1

    Participant reported measure of sleep disturbance. This is scored using the standardized T-scores with a general US population mean of 50 and a standard deviation of 10. Higher scores indicate worse outcomes.

    Time frame: Baseline, 6, 12, 18 months

  6. Anxiety as Assessed by the PROMIS-29 v2.1

    Participant reported measure of anxiety. This is scored using the standardized T-scores with a general US population mean of 50 and a standard deviation of 10. Higher scores indicate worse outcomes.

    Time frame: Baseline, 6, 12, 18 months

  7. Depression as Assessed by the PROMIS-29 v2.1

    Participant reported measure of depression. This is scored using the standardized T-scores with a general US population mean of 50 and a standard deviation of 10. Higher scores indicate worse outcomes.

    Time frame: Baseline, 6, 12, 18 months

  8. Social Roles as Assessed by the PROMIS-29 v2.1

    Participant reported measure of satisfaction with participation in social roles. This is scored using the standardized T-scores with a general US population mean of 50 and a standard deviation of 10. Lower scores indicate worse outcomes.

    Time frame: Baseline, 6, 12, 18 months

Secondary outcomes

  1. ElderTree Days of Use

    Amount of ElderTree (ET) use will be calculated by the number of days.

    Time frame: up to 12 months

  2. Physical Function as Assessed by PROMIS-43

    Participant reported measure of overall health and level of physical disability. This is scored using the standardized T-scores with a general US population mean of 50 and a standard deviation of 10. Lower scores indicate worse outcomes.

    Time frame: Baseline, 6, 12, 18 months

  3. Pain Interference as Assessed by PROMIS-43

    Participant reported measure of pain interference. This is scored using the standardized T-scores with a general US population mean of 50 and a standard deviation of 10. Higher scores indicate worse outcomes.

    Time frame: Baseline, 6, 12, 18 months

  4. Fatigue as Assessed by PROMIS-43

    Participant reported measure of fatigue. This is scored using the standardized T-scores with a general US population mean of 50 and a standard deviation of 10. Higher scores indicate worse outcomes.

    Time frame: Baseline, 6, 12, 18 months

  5. Sleep Disturbance as Assessed by PROMIS-43

    Participant reported measure of sleep disturbance. This is scored using the standardized T-scores with a general US population mean of 50 and a standard deviation of 10. Higher scores indicate worse outcomes.

    Time frame: Baseline, 6, 12, 18 months

  6. Anxiety as Assessed by PROMIS-43

    Participant reported measure of anxiety. This is scored using the standardized T-scores with a general US population mean of 50 and a standard deviation of 10. Higher scores indicate worse outcomes.

    Time frame: Baseline, 6, 12, 18 months

  7. Depression as Assessed by PROMIS-43

    Participant reported measure of depression. This is scored using the standardized T-scores with a general US population mean of 50 and a standard deviation of 10. Higher scores indicate worse outcomes.

    Time frame: Baseline, 6, 12, 18 months

  8. Social Roles as Assessed by PROMIS-43

    Participant reported measure of satisfaction with participation in social roles. This is scored using the standardized T-scores with a general US population mean of 50 and a standard deviation of 10. Lower scores indicate worse outcomes.

    Time frame: Baseline, 6, 12, 18 months

  9. Lorig Health Distress Scale Score

    Health distress was measured using the 4-item Lorig Health Distress Scale. The items asked participants to answer regarding the past month. The measure was scored by averaging the items; with higher values indicating more health distress. Possible range is 0 to 5.

    Time frame: Baseline, 6, 12, 18 months

  10. NIH Toolbox Loneliness Survey Scores

    NIH Toolbox Loneliness Survey is a self-report measure that assesses perceptions of loneliness. This is scored using the standardized T-scores with a general US population mean of 50 and a standard deviation of 10. Higher scores indicate greater perceived loneliness.

    Time frame: Baseline, 6, 12, 18 months

  11. Number of Unscheduled Healthcare Visits

    Participants report at each survey time point the number of urgent care clinic visits, emergency room visits, and overnight hospital stays in the past month.

    Time frame: Baseline, 6, 12, 18 months

  12. Number of Falls in the Previous 6 Months

    The number of falls in the last 6 months

    Time frame: Baseline, 6, 12, 18 months

07

Results

Posted Oct 20, 2026

Participant flow

Participant flow — Overall Study
MilestoneElderTree on Laptop (ET-LT)ElderTree on Smart System (ET-SS)
Started251251
Completed159170
Not completed9281
Withdrew: Intervention no longer supported6352
Withdrew: Lost to follow-up2929

Outcome measures

PrimaryPhysical Function as Assessed by the Patient-Reported Outcomes Measurement Information System (PROMIS) 29 v2.1

Participant reported measure of overall health and level of physical disability. This is scored using the standardized T-scores with a general US population mean of 50 and a standard deviation of 10. Lower scores indicate worse outcomes.

Time frame:
Baseline, 6, 12, 18 months
Reported as:
Mean · T-score
Physical Function as Assessed by the Patient-Reported Outcomes Measurement Information System (PROMIS) 29 v2.1
T-scoreElderTree on Laptop (ET-LT)ElderTree on Smart System (ET-SS)
Baseline41.95 ± 3.1542.54 ± 3.15
6 months42.47 ± 3.1942.33 ± 3.14
12 months42.59 ± 3.2241.78 ± 3.16
18 months42.46 ± 3.2242.60 ± 3.28
PrimaryPain Interference as Assessed by the PROMIS-29 v2.1

Participant reported measure of pain interference. This is scored using the standardized T-scores with a general US population mean of 50 and a standard deviation of 10. Higher scores indicate worse outcomes.

Time frame:
Baseline, 6, 12, 18 months
Reported as:
Mean · T-score
Pain Interference as Assessed by the PROMIS-29 v2.1
T-scoreElderTree on Laptop (ET-LT)ElderTree on Smart System (ET-SS)
Baseline57.82 ± 2.5857.65 ± 2.55
6 months57.15 ± 2.6256.61 ± 2.73
12 months56.41 ± 2.8356.93 ± 2.58
18 months56.80 ± 2.8357.25 ± 2.61
PrimaryPain Intensity as Assessed by the PROMIS-29 v2.1

Participant reported measure of pain intensity, this is a single question, with a possible score of 0 to 10. Higher scores indicate worse outcomes.

Time frame:
Baseline, 6, 12, 18 months
Reported as:
Mean · score on a scale
Pain Intensity as Assessed by the PROMIS-29 v2.1
score on a scaleElderTree on Laptop (ET-LT)ElderTree on Smart System (ET-SS)
Baseline4.03 ± 2.504.17 ± 2.43
6 months3.98 ± 2.483.93 ± 2.48
12 months3.83 ± 2.654.16 ± 2.52
18 months4.04 ± 2.624.07 ± 2.56
PrimaryFatigue as Assessed by the PROMIS-29 v2.1

Participant reported measure of fatigue. This is scored using the standardized T-scores with a general US population mean of 50 and a standard deviation of 10. Higher scores indicate worse outcomes.

Time frame:
Baseline, 6, 12, 18 months
Reported as:
Mean · T-score
Fatigue as Assessed by the PROMIS-29 v2.1
T-scoreElderTree on Laptop (ET-LT)ElderTree on Smart System (ET-SS)
Baseline52.92 ± 2.6853.21 ± 2.69
6 months51.04 ± 2.7752.73 ± 2.72
12 months51.44 ± 2.7952.27 ± 2.77
18 months51.64 ± 2.7652.48 ± 2.80
PrimarySleep as Assessed by the PROMIS-29 v2.1

Participant reported measure of sleep disturbance. This is scored using the standardized T-scores with a general US population mean of 50 and a standard deviation of 10. Higher scores indicate worse outcomes.

Time frame:
Baseline, 6, 12, 18 months
Reported as:
Mean · T-score
Sleep as Assessed by the PROMIS-29 v2.1
T-scoreElderTree on Laptop (ET-LT)ElderTree on Smart System (ET-SS)
Baseline52.96 ± 3.6052.99 ± 3.63
6 months52.62 ± 3.6152.39 ± 3.58
12 months52.79 ± 3.5652.66 ± 3.63
18 months52.15 ± 3.6352.14 ± 3.66
PrimaryAnxiety as Assessed by the PROMIS-29 v2.1

Participant reported measure of anxiety. This is scored using the standardized T-scores with a general US population mean of 50 and a standard deviation of 10. Higher scores indicate worse outcomes.

Time frame:
Baseline, 6, 12, 18 months
Reported as:
Mean · T-score
Anxiety as Assessed by the PROMIS-29 v2.1
T-scoreElderTree on Laptop (ET-LT)ElderTree on Smart System (ET-SS)
Baseline52.09 ± 3.7152.34 ± 3.84
6 months50.58 ± 3.9451.09 ± 3.97
12 months50.92 ± 3.9650.86 ± 4.10
18 months50.80 ± 4.0250.67 ± 4.14
PrimaryDepression as Assessed by the PROMIS-29 v2.1

Participant reported measure of depression. This is scored using the standardized T-scores with a general US population mean of 50 and a standard deviation of 10. Higher scores indicate worse outcomes.

Time frame:
Baseline, 6, 12, 18 months
Reported as:
Mean · T-score
Depression as Assessed by the PROMIS-29 v2.1
T-scoreElderTree on Laptop (ET-LT)ElderTree on Smart System (ET-SS)
Baseline51.28 ± 3.7052.43 ± 3.53
6 months48.87 ± 4.1750.39 ± 3.87
12 months49.24 ± 4.1750.73 ± 3.92
18 months49.20 ± 4.2050.41 ± 4.01
PrimarySocial Roles as Assessed by the PROMIS-29 v2.1

Participant reported measure of satisfaction with participation in social roles. This is scored using the standardized T-scores with a general US population mean of 50 and a standard deviation of 10. Lower scores indicate worse outcomes.

Time frame:
Baseline, 6, 12, 18 months
Reported as:
Mean · T-score
Social Roles as Assessed by the PROMIS-29 v2.1
T-scoreElderTree on Laptop (ET-LT)ElderTree on Smart System (ET-SS)
Baseline48.83 ± 2.8348.27 ± 2.67
6 months49.18 ± 2.7748.57 ± 2.72
12 months49.46 ± 2.9149.28 ± 2.80
18 months48.75 ± 2.8449.35 ± 2.89
SecondaryElderTree Days of Use

Amount of ElderTree (ET) use will be calculated by the number of days.

Time frame:
up to 12 months
Reported as:
Mean · Days
ElderTree Days of Use
DaysElderTree on Laptop (ET-LT)ElderTree on Smart System (ET-SS)
Months 1-630.38 ± 18.9923.40 ± 15.11
Months 7-1221.10 ± 15.9914.17 ± 12.35
SecondaryPhysical Function as Assessed by PROMIS-43

Participant reported measure of overall health and level of physical disability. This is scored using the standardized T-scores with a general US population mean of 50 and a standard deviation of 10. Lower scores indicate worse outcomes.

Time frame:
Baseline, 6, 12, 18 months
Reported as:
Mean · T-score
Physical Function as Assessed by PROMIS-43
T-scoreElderTree on Laptop (ET-LT)ElderTree on Smart System (ET-SS)
Baseline37.46 ± 3.8137.44 ± 3.85
6 months36.90 ± 3.9437.07 ± 3.84
12 months36.76 ± 3.8436.40 ± 3.88
18 months37.17 ± 3.8136.53 ± 3.84
SecondaryPain Interference as Assessed by PROMIS-43

Participant reported measure of pain interference. This is scored using the standardized T-scores with a general US population mean of 50 and a standard deviation of 10. Higher scores indicate worse outcomes.

Time frame:
Baseline, 6, 12, 18 months
Reported as:
Mean · T-score
Pain Interference as Assessed by PROMIS-43
T-scoreElderTree on Laptop (ET-LT)ElderTree on Smart System (ET-SS)
Baseline53.88 ± 3.7954.22 ± 3.70
6 months52.83 ± 3.9052.57 ± 3.98
12 months53.14 ± 4.2253.52 ± 3.72
18 months53.26 ± 3.9753.53 ± 3.86
SecondaryFatigue as Assessed by PROMIS-43

Participant reported measure of fatigue. This is scored using the standardized T-scores with a general US population mean of 50 and a standard deviation of 10. Higher scores indicate worse outcomes.

Time frame:
Baseline, 6, 12, 18 months
Reported as:
Mean · T-score
Fatigue as Assessed by PROMIS-43
T-scoreElderTree on Laptop (ET-LT)ElderTree on Smart System (ET-SS)
Baseline52.51 ± 3.7851.87 ± 3.77
6 months51.46 ± 3.8851.10 ± 3.88
12 months51.07 ± 4.0251.79 ± 3.88
18 months51.48 ± 3.9451.37 ± 4.02
SecondarySleep Disturbance as Assessed by PROMIS-43

Participant reported measure of sleep disturbance. This is scored using the standardized T-scores with a general US population mean of 50 and a standard deviation of 10. Higher scores indicate worse outcomes.

Time frame:
Baseline, 6, 12, 18 months
Reported as:
Mean · T-score
Sleep Disturbance as Assessed by PROMIS-43
T-scoreElderTree on Laptop (ET-LT)ElderTree on Smart System (ET-SS)
Baseline53.47 ± 5.2151.83 ± 5.27
6 months52.43 ± 5.3252.29 ± 5.20
12 months52.22 ± 5.2452.85 ± 5.26
18 months52.16 ± 5.2651.78 ± 5.28
SecondaryAnxiety as Assessed by PROMIS-43

Participant reported measure of anxiety. This is scored using the standardized T-scores with a general US population mean of 50 and a standard deviation of 10. Higher scores indicate worse outcomes.

Time frame:
Baseline, 6, 12, 18 months
Reported as:
Mean · T-score
Anxiety as Assessed by PROMIS-43
T-scoreElderTree on Laptop (ET-LT)ElderTree on Smart System (ET-SS)
Baseline50.60 ± 4.9650.57 ± 4.95
6 months49.12 ± 5.1949.39 ± 5.14
12 months50.28 ± 5.0848.96 ± 5.24
18 months49.58 ± 5.1149.16 ± 5.25
SecondaryDepression as Assessed by PROMIS-43

Participant reported measure of depression. This is scored using the standardized T-scores with a general US population mean of 50 and a standard deviation of 10. Higher scores indicate worse outcomes.

Time frame:
Baseline, 6, 12, 18 months
Reported as:
Mean · T-score
Depression as Assessed by PROMIS-43
T-scoreElderTree on Laptop (ET-LT)ElderTree on Smart System (ET-SS)
Baseline49.43 ± 4.5249.58 ± 4.56
6 months47.88 ± 4.7946.64 ± 4.96
12 months47.55 ± 4.7947.92 ± 4.76
18 months46.62 ± 4.9347.38 ± 4.88
SecondarySocial Roles as Assessed by PROMIS-43

Participant reported measure of satisfaction with participation in social roles. This is scored using the standardized T-scores with a general US population mean of 50 and a standard deviation of 10. Lower scores indicate worse outcomes.

Time frame:
Baseline, 6, 12, 18 months
Reported as:
Mean · T-score
Social Roles as Assessed by PROMIS-43
T-scoreElderTree on Laptop (ET-LT)ElderTree on Smart System (ET-SS)
Baseline50.49 ± 3.8250.78 ± 3.77
6 months50.60 ± 3.7651.30 ± 3.73
12 months51.03 ± 3.8851.51 ± 3.84
18 months51.24 ± 3.9251.20 ± 3.87
SecondaryLorig Health Distress Scale Score

Health distress was measured using the 4-item Lorig Health Distress Scale. The items asked participants to answer regarding the past month. The measure was scored by averaging the items; with higher values indicating more health distress. Possible range is 0 to 5.

Time frame:
Baseline, 6, 12, 18 months
Reported as:
Mean · score on a scale
Lorig Health Distress Scale Score
score on a scaleElderTree on Laptop (ET-LT)ElderTree on Smart System (ET-SS)
Baseline1.93 ± 1.141.87 ± 1.14
6 months1.63 ± 1.101.67 ± 1.13
12 months1.61 ± 1.171.68 ± 1.12
18 months1.66 ± 1.221.60 ± 1.14
SecondaryNIH Toolbox Loneliness Survey Scores

NIH Toolbox Loneliness Survey is a self-report measure that assesses perceptions of loneliness. This is scored using the standardized T-scores with a general US population mean of 50 and a standard deviation of 10. Higher scores indicate greater perceived loneliness.

Time frame:
Baseline, 6, 12, 18 months
Reported as:
Mean · T-score
NIH Toolbox Loneliness Survey Scores
T-scoreElderTree on Laptop (ET-LT)ElderTree on Smart System (ET-SS)
Baseline55.65 ± 3.5154.96 ± 3.62
6 months52.78 ± 3.6653.74 ± 3.70
12 months52.64 ± 3.7153.61 ± 3.70
18 months52.85 ± 3.7352.39 ± 3.84
SecondaryNumber of Unscheduled Healthcare Visits

Participants report at each survey time point the number of urgent care clinic visits, emergency room visits, and overnight hospital stays in the past month.

Time frame:
Baseline, 6, 12, 18 months
Reported as:
Mean · unscheduled healthcare visits
Number of Unscheduled Healthcare Visits
unscheduled healthcare visitsElderTree on Laptop (ET-LT)ElderTree on Smart System (ET-SS)
Baseline0.33 ± 1.200.33 ± 1.42
6 months0.46 ± 1.480.35 ± 0.79
12 months0.36 ± 0.990.36 ± 0.94
18 months0.33 ± 0.890.44 ± 2.14
SecondaryNumber of Falls in the Previous 6 Months

The number of falls in the last 6 months

Time frame:
Baseline, 6, 12, 18 months
Reported as:
Mean · falls
Number of Falls in the Previous 6 Months
fallsElderTree on Laptop (ET-LT)ElderTree on Smart System (ET-SS)
Baseline1.01 ± 3.930.58 ± 0.97
6 months0.60 ± 1.330.53 ± 1.20
12 months0.82 ± 1.800.60 ± 1.10
18 months0.55 ± 1.170.59 ± 1.20

Adverse events

Collected over From 6 month until 18 month follow-up. Non-serious events are listed at a 0% frequency threshold.

Adverse event summary by group
GroupDeathsSeriousOther
ElderTree on Laptop (ET-LT)5/188 (2.7%)0/188 (0%)0/188 (0%)
ElderTree on Smart System (ET-SS)2/199 (1%)0/199 (0%)0/199 (0%)

Baseline characteristics

Age, Continuous
Age, Continuous(years)ElderTree on Laptop (ET-LT) - Initial InterventionElderTree on Smart System (ET-SS) - Initial InterventionElderTree on Laptop (ET-LT) - FinalElderTree on Smart System (ET-SS) - FinalTotal
Mean70.08 ± 7.0468.88 ± 6.8070.06 ± 6.8669.68 ± 6.1069.87 ± 6.48
Sex: Female, Male
Sex: Female, Male(Participants)ElderTree on Laptop (ET-LT) - Initial InterventionElderTree on Smart System (ET-SS) - Initial InterventionElderTree on Laptop (ET-LT) - FinalElderTree on Smart System (ET-SS) - FinalTotal
Female4232127134335
Male21206165167
Race/Ethnicity, Customized
Race/Ethnicity, Customized(Participants)ElderTree on Laptop (ET-LT) - Initial InterventionElderTree on Smart System (ET-SS) - Initial InterventionElderTree on Laptop (ET-LT) - FinalElderTree on Smart System (ET-SS) - FinalTotal
Ethnicity — Hispanic or Latino origin10348
Ethnicity — Non-Hispanic6252185195494
Region of Enrollment
Region of Enrollment(participants)ElderTree on Laptop (ET-LT) - Initial InterventionElderTree on Smart System (ET-SS) - Initial InterventionElderTree on Laptop (ET-LT) - FinalElderTree on Smart System (ET-SS) - FinalTotal
United States6352188199502
Number of chronic conditions
Number of chronic conditions(chronic conditions)ElderTree on Laptop (ET-LT) - Initial InterventionElderTree on Smart System (ET-SS) - Initial InterventionElderTree on Laptop (ET-LT) - FinalElderTree on Smart System (ET-SS) - FinalTotal
Mean6.0 ± 1.956.38 ± 1.766.85 ± 1.537.08 ± 1.706.44 ± 0.05
08

Study locations

1 site
  • University of Wisconsin
    Madison, Wisconsin 53705, United States
09

References and documents

Publications

  • Gustafson DH Sr, Mares ML, Johnston DC, Curtin JJ, Pe-Romashko K, Landucci G. Comparison of Smart Display Versus Laptop Platforms for an eHealth Intervention to Improve Functional Health for Older Adults With Multiple Chronic Conditions: Protocol for a Randomized Clinical Trial. JMIR Res Protoc. 2025 Apr 3;14:e64449. doi: 10.2196/64449. PubMed 40080672 ↗

Study documents

PDFs hosted by the registry, ClinicalTrials.gov.

Individual participant data

Plan to share: No

10

Updates

1 registry update since Sep 25, 2026
Results
Results posted
posted Oct 20, 2026
Primary outcomes
8 edited
What changed in the outcomes
  • EditedChange in physical functionPhysical Function as assessedAssessed by the Patient-Reported Outcomes Measurement Information System (PROMIS) 29 v2.1Time frame: Baseline, 6, 12, 18 months
  • EditedChange in pain interferencePain Interference as assessedAssessed by the PROMIS-29 v2.1Time frame: Baseline, 6, 12, 18 months
  • EditedChange in pain intensityPain Intensity as assessedAssessed by the PROMIS-29 v2.1Time frame: Baseline, 6, 12, 18 months
  • EditedChange in fatigueFatigue as assessedAssessed by the PROMIS-29 v2.1Time frame: Baseline, 6, 12, 18 months
  • EditedChange in sleepSleep as assessedAssessed by the PROMIS-29 v2.1Time frame: Baseline, 6, 12, 18 months
  • EditedChange in anxietyAnxiety as assessedAssessed by the PROMIS-29 v2.1Time frame: Baseline, 6, 12, 18 months
  • EditedChange in depressionDepression as assessedAssessed by the PROMIS-29 v2.1Time frame: Baseline, 6, 12, 18 months
  • EditedChange in social rolesSocial Roles as assessedAssessed by the PROMIS-29 v2.1Time frame: Baseline, 6, 12, 18 months
Oct 20, 2026
Documents
Oct 20, 2026
Secondary outcomes
11 edited
What changed in the outcomes
  • EditedChange in Physical Function as assessedAssessed by PROMIS-43Time frame: Baseline, 6, 12, 18 months
  • EditedChange in Pain Interference as assessedAssessed by PROMIS-43Time frame: Baseline, 6, 12, 18 months
  • EditedChange in Fatigue as assessedAssessed by PROMIS-43Time frame: Baseline, 6, 12, 18 months
  • EditedChange in Sleep Disturbance as assessedAssessed by PROMIS-43Time frame: Baseline, 6, 12, 18 months
  • EditedChange in Anxiety as assessedAssessed by PROMIS-43Time frame: Baseline, 6, 12, 18 months
  • EditedChange in Depression as assessedAssessed by PROMIS-43Time frame: Baseline, 6, 12, 18 months
  • EditedChange in Social Roles as assessedAssessed by PROMIS-43Time frame: Baseline, 6, 12, 18 months
  • EditedChange in Lorig Health Distress Scale ScoreTime frame: Baseline, 6, 12, 18 months
  • EditedChange in NIH Toolbox Loneliness Survey scoresScoresTime frame: Baseline, 6, 12, 18 months
  • ChangedBefore Change in FallsNow Number of Falls in the Previous 6 MonthsTime frame: Baseline, 6, 12, 18 months
  • ChangedBefore Change in overall ElderTree use across the 12-month interventionNow ElderTree Days of UseTime frame: up to 12 months
Oct 20, 2026
Show all 1 update
  1. Oct 20, 2026
    Results posted
    Documents Protocol and statistical analysis plan ↗ posted
    Primary outcomes 8 edited
    What changed in the outcomes
    • EditedChange in physical functionPhysical Function as assessedAssessed by the Patient-Reported Outcomes Measurement Information System (PROMIS) 29 v2.1Time frame: Baseline, 6, 12, 18 months
    • EditedChange in pain interferencePain Interference as assessedAssessed by the PROMIS-29 v2.1Time frame: Baseline, 6, 12, 18 months
    • EditedChange in pain intensityPain Intensity as assessedAssessed by the PROMIS-29 v2.1Time frame: Baseline, 6, 12, 18 months
    • EditedChange in fatigueFatigue as assessedAssessed by the PROMIS-29 v2.1Time frame: Baseline, 6, 12, 18 months
    • EditedChange in sleepSleep as assessedAssessed by the PROMIS-29 v2.1Time frame: Baseline, 6, 12, 18 months
    • EditedChange in anxietyAnxiety as assessedAssessed by the PROMIS-29 v2.1Time frame: Baseline, 6, 12, 18 months
    • EditedChange in depressionDepression as assessedAssessed by the PROMIS-29 v2.1Time frame: Baseline, 6, 12, 18 months
    • EditedChange in social rolesSocial Roles as assessedAssessed by the PROMIS-29 v2.1Time frame: Baseline, 6, 12, 18 months
    Secondary outcomes 11 edited
    What changed in the outcomes
    • EditedChange in Physical Function as assessedAssessed by PROMIS-43Time frame: Baseline, 6, 12, 18 months
    • EditedChange in Pain Interference as assessedAssessed by PROMIS-43Time frame: Baseline, 6, 12, 18 months
    • EditedChange in Fatigue as assessedAssessed by PROMIS-43Time frame: Baseline, 6, 12, 18 months
    • EditedChange in Sleep Disturbance as assessedAssessed by PROMIS-43Time frame: Baseline, 6, 12, 18 months
    • EditedChange in Anxiety as assessedAssessed by PROMIS-43Time frame: Baseline, 6, 12, 18 months
    • EditedChange in Depression as assessedAssessed by PROMIS-43Time frame: Baseline, 6, 12, 18 months
    • EditedChange in Social Roles as assessedAssessed by PROMIS-43Time frame: Baseline, 6, 12, 18 months
    • EditedChange in Lorig Health Distress Scale ScoreTime frame: Baseline, 6, 12, 18 months
    • EditedChange in NIH Toolbox Loneliness Survey scoresScoresTime frame: Baseline, 6, 12, 18 months
    • ChangedBefore Change in FallsNow Number of Falls in the Previous 6 MonthsTime frame: Baseline, 6, 12, 18 months
    • ChangedBefore Change in overall ElderTree use across the 12-month interventionNow ElderTree Days of UseTime frame: up to 12 months
    + 3 other changes: verification date, description and arm descriptions

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

11

Registry details

Key details

Study ID
NCT05240534
Lead sponsor
University of Wisconsin, Madison
Collaborators
National Heart, Lung, and Blood Institute (NHLBI)
Responsible party
Sponsor
First posted
Feb 15, 2022
Start date
Apr 29, 2022
Primary completion
Dec 3, 2025
Completion
Dec 3, 2025
Results posted
Oct 20, 2026
Last update
Oct 20, 2026

Study contacts

David H Gustafson, PhD
principal investigator · University of Wisconsin, Madison

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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