An observational study in Acute Hypoxemic Respiratory Failure, sponsored by University of Milano Bicocca. Completed at 8 sites in 5 countries. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-05-30.
Sponsored by University of Milano Bicocca · Observational
To verify the association between respiratory system mechanical properties (ΔP, ΔPL,dyn, Pmus, Pplat and CRS and CL,dyn) assessed during assisted modes of ventilation (as average over the first three days since enrollment) and ICU mortality.
1,650 studies on the registry are indexed under Respiratory Insufficiency; 296 are open to participants now.
This study's enrollment of 298 is above the median of 100 across 545 observational studies indexed under Respiratory Insufficiency.
Browse Respiratory Insufficiency studies →University of Milano Bicocca is the lead sponsor of 124 studies on the registry; 48 are open to participants now.
Counted across the registry records on this site, refreshed daily.
AHRF/ARDS patients on Assisted Mechanical Ventilation modes from international centers will be enrolled. All the pressure-targeted modes of assisted ventilation will be acceptable for the study inclusion.
Exclusion Criteria:
Correlation between respiratory system mechanical properties and ICU mortality
Difference between mean values of driving pressure in survivors and non-survivors at ICU discharge.
Time frame: 90 days
Correlation between respiratory system compliance and ICU mortality
Difference between mean values of respiratory system compliance in survivors and non-survivors at ICU discharge.
Time frame: 90 days
Correlation between plateau pressure and ICU mortality
Difference between mean values of plateau pressure in survivors and non-survivors at ICU discharge.
Time frame: 90 days
Correlation between pressure muscle index and ICU mortality
Difference between mean values of pressure muscle index (PMI) in survivors and non-survivors at ICU discharge.
Time frame: 90 days
Correlation between muscle pressure and ICU mortality
Difference between mean values of muscle pressure (Pmus) in survivors and non-survivors at ICU discharge.
Time frame: 90 days
This study is completed, as verified in May 2025. You cannot join it, but the record below documents what was studied.
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University of Milano Bicocca