An observational study in Coronary Artery Aneurysm, Abdominal Aortic Aneurysm and Coronary Disease, sponsored by John Paul II Hospital, Krakow. Recruiting at 1 site in Poland. Open to participants aged 18 Years to 85 Years. Per ClinicalTrials.gov, last updated 2022-01-10.
Sponsored by John Paul II Hospital, Krakow · Observational
The main objective of the CARE-ANEURYSM project is to evaluate inflammation and clotting abnormalities in patients with aneurysmal coronary artery disease in relation to patients with abdominal aortic aneurysm or coronary artery disease (acting as controls).
The trial will enrol 180 patients, 60 in each of three groups: 1) aneurysmal coronary artery disease; 2) abdominal aortic aneurysm; 3) coronary artery disease. In addition, up to 250 patients with aneurysmal coronary disease will be follow for clinical outcomes in relation to controls (prognosis group).
The primary research question of this project is to evaluate wheter the inflammation and clotting abnormalities in patients with aneurysmal coronary artery disease differ from ones in abdominal aortic aneurysm or coronary artery diseases. Study endpoints include the level of inflammation biomarkers and fibrin clot properties in each cohort.
31 studies on the registry are indexed under Coronary Aneurysm; 10 are open to participants now.
This study's planned enrollment of 180 is above the median of 100 across 13 observational studies indexed under Coronary Aneurysm.
Browse Coronary Aneurysm studies →John Paul II Hospital, Krakow is the lead sponsor of 16 studies on the registry; 6 are open to participants now.
Counted across the registry records on this site, refreshed daily.
All-comer, consecutive patients with the contiontds under the evaluation in this study will be screen for enrolment.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The New York Heart Association’s four classes of how much heart failure limits physical activity.
Studies set their own limit — many outside heart failure leave out class III–IV, while heart failure studies may ask for a particular class. Check the class this study names.
NYHA class (heart failure)
The New York Heart Association’s four classes of how much heart failure limits physical activity.
Studies set their own limit — many outside heart failure leave out class III–IV, while heart failure studies may ask for a particular class. Check the class this study names.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Patients with coronary artery ectasia or/and aneurysm diagnosed during coronary angiography
Other: Evaluation of inflammation and clotting
Patients with diagnosed with abdominal aortic aneurysm
Other: Evaluation of inflammation and clotting
Patients with diagnosed with coronary artery disease
Other: Evaluation of inflammation and clotting
Evaluation of inflammation biomarkers (such as 8-isoprostane, Il-6) and fibrin clot properties (such as clot lysis time, clot permeability)
Inflammation
Level of inflammation biomarkers (such as 8-isoprostane, Il-6) in each group
Time frame: Baseline (at enrolment)
Clotting
Fibrin clot properties (such as clot lysis time, clot permeability) in each group
Time frame: Baseline (at enrolment)
Composite Clinical outcome after 1 year
Death, stroke, myocardial infarction
Time frame: 1 year after the enrolment
Composite Clinical outcome after 5 years
Death, stroke, myocardial infarction
Time frame: 5 years after the enrolment
Plan to share: Undecided
Start is estimated for Jan 2022; primary completion for Sep 2024, 32 months later.
How these figures are worked out, and which studies are left out of them.
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John Paul II Hospital, Krakow