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CompletedNCT05174208Updated Apr 29, 2026

Study of Imaginomics Predicting Early Surgical Rates in Crohn's Disease

An observational study in Crohn Disease, Prognostic Model and Radiomics, sponsored by Sixth Affiliated Hospital, Sun Yat-sen University. Completed at 1 site in China. Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2026-04-29.

Sponsored by Sixth Affiliated Hospital, Sun Yat-sen University · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
300
Ages
18 Years to 65 Years
Sex
All
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Study summary

Crohn's disease (CD), a type of inflammatory bowel disease (IBD), is a chronic intestinal recurrent inflammatory disease involving the entire digestive tract. Most CD patients require surgery for complications, including stenosis, perforation, and severe intestinal bleeding. Predicting early-onset surgery risk is of great importance to assist launching of therapeutic strategies. We aim to establish a digital prognostic model and nomogram using radiomics, which will help clinical practice.

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Conditions studied

  • Crohn Disease
  • Prognostic Model
  • Radiomics

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In context

Crohn Disease

1,880 studies on the registry are indexed under Crohn Disease; 462 are open to participants now.

This study's enrollment of 300 is above the median of 162 across 608 observational studies indexed under Crohn Disease.

Browse Crohn Disease studies →

Lead sponsor

Sixth Affiliated Hospital, Sun Yat-sen University is the lead sponsor of 211 studies on the registry; 110 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

2017-2020 CD patients in the IBD center of Sixth Affiliated Hospital of Sun Yat-Sen University.

Inclusion criteria

patients with a confirmed diagnosis of CD; a follow-up more than 1 year; without previous CD-associated intestinal surgeries; complete data of CTE.

Exclusion criteria

Exclusion Criteria:

patients without a confirmed diagnosis of CD; with incomplete data and a follow-up less than 1 year; patients have previous intestinal surgeries; patients who have never undergone CTE examination.

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Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
300 participants (actual)
Patient registry
No

Groups and cohorts

  • CD

    Other: CTE examination

Interventions

  • OtherCTE examination

    each patients should have undergone CTE examination

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What researchers measure

Primary outcomes

  1. percentages of surgery at one-year after diagnosis

    percentages of surgery at one-year after diagnosis

    Time frame: 2017-2021

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Study locations

1 site
  • the Sixth Affiliated Hospital of Sun Yat-Sen University
    Guangzhou, Guangdong 501655, China
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 29, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT05174208
Lead sponsor
Sixth Affiliated Hospital, Sun Yat-sen University
Responsible party
Sponsor
First posted
Dec 30, 2021
Start date
Jan 1, 2022
Primary completion
Sep 20, 2024
Completion
Dec 20, 2024
Last update
Apr 29, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Apr 2026. You cannot join it, but the record below documents what was studied.

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