ClinicalTrials.gg
CompletedNCT05155475ECCOUpdated Jul 16, 2026

Endoscopic Ultrasound Evaluation of the Common Bile Duct in Patients With Obstructive Jaundice Due to Bilio-pancreatic Malignancies (ECCO Trial)

An observational study in Obstructive Jaundice and Bilio-pancreatic Tumor, sponsored by GCS Ramsay Santé pour l'Enseignement et la Recherche. Completed at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-07-16.

Sponsored by GCS Ramsay Santé pour l'Enseignement et la Recherche · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
20
Ages
18 Years and older
Sex
All
01

Study summary

To assess the size of the common bile duct in a large cohort of patients with jaundice following a malignant tumor of the head of the pancreas or the distal bile duct receiving a diagnostic EA for biopsy and / or for evaluation of tissue resectability.

02

Conditions studied

  • Obstructive Jaundice
  • Bilio-pancreatic Tumor

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03

In context

Jaundice, Obstructive

62 studies on the registry are indexed under Jaundice, Obstructive; 15 are open to participants now.

This study's enrollment of 20 is below the median of 125 across 20 observational studies indexed under Jaundice, Obstructive.

Browse Jaundice, Obstructive studies →

Lead sponsor

GCS Ramsay Santé pour l'Enseignement et la Recherche is the lead sponsor of 207 studies on the registry; 99 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients over 18 years old, with jaundice

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Patients with jaundice and an injury to the head of the pancreas recommended for EUS-guided tissue acquisition or staging
  • Patients with jaundice and distal CBD lesion suggestive of cholangiocarcinoma or Vater's ampulla carcinoma recommended for EUS-guided tissue acquisition or staging
  • Serum level ≥ 3 mg / dl
  • Age ≥ 18 years old
  • Subject affiliated or beneficiary of a social security scheme.
  • Subject having been informed of this study and having given his no objection

Exclusion criteria

Exclusion Criteria:

  • Presence of altered anatomy due to previous gastric surgery (Billroth II or Roux-en-Y anastomosis)
  • Sphincterotomy performed previously, plastic biliary stent or metal stent placement
  • Percutaneous drainage of the bile ducts performed previously
  • Pregnant, breastfeeding or parturient woman
  • Protected patients: Adults under guardianship, curatorship or other legal protection, deprived of their liberty by judicial or administrative decision; hospitalized without consent.
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Bilirubin

A yellow substance made when red blood cells are broken down, which the liver clears. A high level can mean a problem with the liver or the bile ducts.

Criteria often allow more for people with Gilbert’s syndrome, a harmless inherited condition that raises bilirubin.

05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
20 participants (actual)
Patient registry
No

Groups and cohorts

  • Patient with jaundice

    Procedure: Ultrasound endoscopy

Interventions

  • ProcedureUltrasound endoscopy

    After identification of the lesion, the common bile duct will be identified and followed by the point of dilation due to the compression of the known lesion up to the hilum of the liver

06

What researchers measure

Primary outcomes

  1. Evaluation of the common bile duct size

    Time frame: 1 day

07

Study locations

1 site
  • Hôpital Jean Mermoz
    Lyon, 69008 Lyon, France
08

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Ran from Jun 2019 to primary completion in Dec 2019, 6 months.

How these figures are worked out, and which studies are left out of them.

Registered
Nov 30, 2021
First posted
Dec 13, 2021
StartActual
Jun 4, 2019
Primary completionActual
Dec 4, 2019
CompletionActual
Dec 18, 2019
Last update
Jul 16, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Jul 16, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT05155475
Collaborators
European Clinical Trial Experts Network
Responsible party
Sponsor
First posted
Dec 13, 2021
Start date
Jun 4, 2019
Primary completion
Dec 4, 2019
Completion
Dec 18, 2019
Last update
Jul 16, 2026

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jul 2026. You cannot join it, but the record below documents what was studied.

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Discussion

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