An observational study in Preeclampsia, Recurrence and Hypertension, sponsored by Dunjin Chen. Status unknown at 1 site in China. Open to female participants aged 19 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2021-12-08.
Sponsored by Dunjin Chen · Observational
The purpose of this study is to evaluate the risk factors of recurrent preeclampsia and compare the short-term and long-term adverse outcomes of women and their offspring.
The investigators collected women delivered twice in a row in our hospital. The investigators divided these pregnant women into three groups. Women in the first group did not complicate preeclampsia at both deliveries; Women in the second group complicated preeclampsia at the first delivery or at the second delivery; women in the third group complicated preeclampsia at two deliveries. The investigators explore the risk factors of recurrent preeclampsia and measure blood pressure, blood lipids, thyroid function, glycosylated hemoglobin, ALT, AST, et al. in one year, three years, and five years after the second delivery.
882 studies on the registry are indexed under Pre-Eclampsia; 237 are open to participants now.
This study's planned enrollment of 1,000 is above the median of 163 across 380 observational studies indexed under Pre-Eclampsia.
Browse Pre-Eclampsia studies →Dunjin Chen is the lead sponsor of 6 studies on the registry; 1 is open to participants now.
Counted across the registry records on this site, refreshed daily.
women with at least twice of delivery history are divided into three groups, control group refers to women without preeclampsia history, the second group refers to women complicated with preeclampsia at the first delivery or at the second delivery, the third group refers to women complicated with preeclampsia at two deliveries.
Exclusion Criteria:
pregnancy without preeclampsia
Other: blood pressure,BMI, blood sample
pregnancy complicated with preeclampsia at the first delivery or at the second delivery
Other: blood pressure,BMI, blood sample
pregnancy complicated with preeclampsia at two deliveries
Other: blood pressure,BMI, blood sample
Blood pressure will be monitored. BMI will be measured. Blood samples will be tested.
blood pressure and hypertension of women
blood pressure ≥140/90 mmHg
Time frame: 1year after the second deliver
blood pressure and hypertension of women
blood pressure ≥140/90 mmHg
Time frame: 3 years after the second deliver
blood pressure and hypertension of women
blood pressure ≥140/90 mmHg
Time frame: 5 years after the second deliver
blood pressure and hypertension of offspring
blood pressure≥140/90 mmHg
Time frame: 1 year old
blood pressure and hypertension of offspring
blood pressure≥140/90 mmHg
Time frame: 3 years old
blood pressure and hypertension of offspring
blood pressure≥140/90 mmHg
Time frame: 5 years old
level of glycosylated hemoglobin in blood
women
Time frame: 1 year after the second deliver
level of glycosylated hemoglobin in blood
women
Time frame: 3 years after the second deliver
level of glycosylated hemoglobin in blood
women
Time frame: 5 years after the second deliver
level of cholesterol, LDL, HDL, VLDL-C in blood
women
Time frame: 1 year after the second deliver
level of cholesterol, LDL, HDL, VLDL-C in blood
women
Time frame: 3 years after the second deliver
level of cholesterol, LDL, HDL, VLDL-C in blood
women
Time frame: 5 years after the second deliver
level of FT3,FT4, and hTSH in blood
women
Time frame: 1year after the second deliver
level of FT3,FT4, and hTSH in blood
women
Time frame: 3 years after the second deliver
level of FT3,FT4, and hTSH in blood
women
Time frame: 5 years after the second deliver
level of AST and ALT in blood
women
Time frame: 1year after the second deliver
level of AST and ALT in blood
women
Time frame: 3 years after the second deliver
level of AST and ALT in blood
women
Time frame: 5 years after the second deliver
BMI of offspring
weight(kg)/height(m)2
Time frame: 1 year old
BMI of offspring
weight(kg)/height(m)2
Time frame: 3 years old
BMI of offspring
weight(kg)/height(m)2
Time frame: 5 years old
level of insulin in blood
women
Time frame: 1year after the second deliver
level of insulin in blood
women
Time frame: 3 years after the second deliver
level of insulin in blood
women
Time frame: 5 years after the second deliver
level of fructosamine in blood
women
Time frame: 1year after the second deliver
level of fructosamine in blood
women
Time frame: 3 years after the second deliver
level of fructosamine in blood
women
Time frame: 5 years after the second deliver
level of AI37℃、AI4℃、PRA、ALD、AngII in blood
women
Time frame: 1 year after the second deliver
level of AI37℃、AI4℃、PRA、ALD、AngII in blood
women
Time frame: 3 years after the second deliver
level of AI37℃、AI4℃、PRA、ALD、AngII in blood
women
Time frame: 5 years after the second deliver
Plan to share: No
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This study is status unknown, as verified in Nov 2021. You cannot join it, but the record below documents what was studied.
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Dunjin Chen