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CompletedNCT05121272Updated May 1, 2026

Fatigability and Cognitive Demand With Aging

An interventional study of cognitive task in Fatigue, sponsored by University of Oklahoma. Completed at 1 site in United States. Open to participants aged 18 Years to 90 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-05-01.

Sponsored by University of Oklahoma · Not applicable, Interventional, and Other

Phase
Not applicable
Study type
Interventional
Enrollment
40
Allocation
Randomized
Ages
18 Years to 90 Years
Sex
All
01

Study summary

This study will determine the influence of a cognitive task performed during fatiguing contractions.

Read the detailed description

Individuals will participate in one familiarization session followed by 3 randomized experimental sessions (crossover design).

02

Conditions studied

  • Fatigue

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Keywords

  • sex difference
  • aging
03

In context

Fatigue

1,860 studies on the registry are indexed under Fatigue; 376 are open to participants now.

This study's enrollment of 40 is below the median of 54 across 1,440 interventional studies indexed under Fatigue.

Browse Fatigue studies →

Lead sponsor

University of Oklahoma is the lead sponsor of 424 studies on the registry; 99 are open to participants now.

Of its 42 completed or terminated interventional studies of FDA-regulated products, 16 (38%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 90 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Healthy individuals aged between 18-35 and 65-90

Exclusion criteria

Exclusion Criteria:

  • Metal implants or joint replacement. neuromuscular disease
05

Study design

Phase
Not applicable
Primary purpose
Other
Allocation
Randomized
Intervention model
Single group
Masking
Single (Participant)
Enrollment
40 participants (actual)

Study arms

  • Experimental
    young men

    Individuals will participate in 1 familiarization and 3 test sessions

    Behavioral: cognitive task

  • Experimental
    young women

    Individuals will participate in 1 familiarization and 3 test sessions

    Behavioral: cognitive task

  • Experimental
    older men

    Individuals will participate in 1 familiarization and 3 test sessions

    Behavioral: cognitive task

  • Experimental
    older women

    Individuals will participate in 1 familiarization and 3 test sessions

    Behavioral: cognitive task

Interventions

  • Behavioralcognitive task

    cognitive task

06

What researchers measure

Primary outcomes

  1. force

    Change in force of the arm muscles will be evaluated with a custom made device during each test session

    Time frame: Each session will take approximately 2-3 hours (total of 4 test sessions)

  2. anxiety levels

    changes in anxiety levels quantified with a questionnaire

    Time frame: Each session will take approximately 2-3 hours (total of 4 test sessions

  3. arterial pressure

    changes in arterial pressure will be quantified with a non-invasive device (finometer)

    Time frame: Each session will take approximately 2-3 hours (total of 4 test sessions

  4. fatigue

    changes in fatigue will be assessed with questionnaires

    Time frame: Each session will take approximately 2-3 hours (total of 4 test sessions

07

Study locations

1 site
  • University of Oklahoma
    Norman, Oklahoma 73071, United States
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 1, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT05121272
Lead sponsor
University of Oklahoma
Responsible party
Sponsor
First posted
Nov 16, 2021
Start date
Oct 11, 2021
Primary completion
Aug 15, 2025
Completion
Apr 27, 2026
Last update
May 1, 2026

Study contacts

Hugo Pereira, PhD
principal investigator · University of Oklahoma

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Apr 2026. You cannot join it, but the record below documents what was studied.

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