An interventional study of Brain Neuroimaging in Migraine, Small Vessel Ischemic Disease and Multiple Sclerosis, sponsored by Mayo Clinic. Active, not recruiting at 1 site in United States. Open to female participants aged 20 Years to 59 Years. Per ClinicalTrials.gov, last updated 2026-09-24.
Sponsored by Mayo Clinic · Not applicable, Interventional, and Diagnostic
The purpose of this research is to better understand brain white matter hyperintensities (WMH) in women with migraines
1,528 studies on the registry are indexed under Migraine Disorders; 299 are open to participants now.
This study's planned enrollment of 50 is below the median of 80 across 1,175 interventional studies indexed under Migraine Disorders.
Browse Migraine Disorders studies →Mayo Clinic is the lead sponsor of 3,218 studies on the registry; 670 are open to participants now.
Of its 445 completed or terminated interventional studies of FDA-regulated products, 313 (70%) have results posted.
Counted across the registry records on this site, refreshed daily.
Inclusion Criteria - Migraine (N=20):
Exclusion Criteria:
Inclusion Criteria - SVI disease (n=10):
Exclusion Criteria:
Inclusion Criteria - MS (n=10):
Exclusion Criteria:
Women with migraine and presence of white matter hyperintensities (WMH) on clinical magnetic resonance imaging (MRI) will have brain neuroimaging.
Diagnostic Test: Brain Neuroimaging
Women diagnosed with SVI disease and presence of white matter hyperintensities (WMH) on clinical magnetic resonance imaging (MRI) will have brain neuroimaging.
Diagnostic Test: Brain Neuroimaging
Women diagnosed with MS and presence of white matter hyperintensities (WMH) on clinical magnetic resonance imaging (MRI) will have brain neuroimaging.
Diagnostic Test: Brain Neuroimaging
Non-invasive magnetic resonance imaging sequences will investigate metabolic signatures unique to migraine WMH. Imaging data will be used for development of artificial intelligence (AI) algorithms to classify the cause of WMHs.
WMH imaging disease parameters
Radiological MRI assessment of WMH in migraine
Time frame: 3 months
Plan to share: No
No publications or documents are linked to this record.
This study is active, not recruiting, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.
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