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CompletedNCT05105906Updated Mar 13, 2025

Post-operative Delirium (POD) in Patients Undergoing Hip Fracture Surgery

An observational study in Delirium and Cognitive Dysfunction, sponsored by Fondazione Policlinico Universitario Agostino Gemelli IRCCS. Completed at 1 site in Italy. Open to participants aged 65 Years and older. Per ClinicalTrials.gov, last updated 2025-03-13.

Sponsored by Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Observational

Study type
Observational
Model
Case-control
Time perspective
Other
Enrollment
270
Ages
65 Years and older
Sex
All
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Study summary

The primary endpoint of the study is the appearance of Post Operative Delirium within the first 3 months.

The secondary endpoints are the development of POCD, dementia of any type of new onset at 12 months, mortality at 30 days, postoperative hospitalization time (including rehabilitation performed within the Polyclinic).. The analysis of the risk factors of POD and their correlation with the development of POCD/Dementia in the post-surgery period will provide important information for the optimization of the management path of these patients at an individual level , with inevitable repercussions on the possibility of reintegration into social and family life

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Conditions studied

03

In context

Delirium

1,057 studies on the registry are indexed under Delirium; 238 are open to participants now.

This study's enrollment of 270 is above the median of 200 across 418 observational studies indexed under Delirium.

Browse Delirium studies →

Lead sponsor

Fondazione Policlinico Universitario Agostino Gemelli IRCCS is the lead sponsor of 920 studies on the registry; 529 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
65 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

All men and women over the age of 65 with clinical-radiological hip fracture presence will be enrolled

Inclusion criteria

  • Age > 65
  • Clinical - radiological presence of hip fracture

Exclusion criteria

Exclusion Criteria:

  • Age \<65
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Study design

Observational model
Case-control
Time perspective
Other
Enrollment
270 participants (actual)
Patient registry
No

Interventions

  • Diagnostic testcognitive tests performed

    cognitive tests performed

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What researchers measure

Primary outcomes

  1. Appearance of POD within the first 3 months

    Appearance of Post Operative Delirium within the first 3 months after hip surgery

    Time frame: 3 months assessment

Secondary outcomes

  1. Development of POCD, dementia of any type of new onset at 12 months, mortality at 30 days, postoperative hospitalization time

    Development of Post Operative Cognitive Dysfunction, dementia of any type of new onset at 12 months, mortality at 30 days, postoperative hospitalization time

    Time frame: 12 months assessment

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Study locations

1 site
  • Fondazione Policlinico Gemelli
    Rome, 00168, Italy
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 13, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT05105906
Lead sponsor
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Responsible party
Giuliano Ferrone (M.D., Fondazione Policlinico Universitario Agostino Gemelli IRCCS) — Principal investigator
First posted
Nov 3, 2021
Start date
May 1, 2021
Primary completion
May 25, 2024
Completion
Dec 30, 2024
Last update
Mar 13, 2025

Study contacts

Giuliano Ferrone
principal investigator · Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Mar 2025. You cannot join it, but the record below documents what was studied.

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