An interventional study of ESPB group and TPVB group in Nerve Block, Analgesia and Pectus Excavatum, sponsored by West China Hospital. Completed at 1 site in China. Open to participants aged 4 Years to 18 Years. Per ClinicalTrials.gov, last updated 2023-11-18.
Sponsored by West China Hospital · Not applicable, Interventional, and Supportive care
This is a prospective randomized double-blind non-inferiority trial designed to test the hypothesis that erector spinae plane block (ESPB) is non-inferior to thoracic paravertebral block (TPVB) in postoperative pain control after pectus excavatum repair.
79 studies on the registry are indexed under Funnel Chest; 10 are open to participants now.
This study's enrollment of 68 is above the median of 40 across 46 interventional studies indexed under Funnel Chest.
Browse Funnel Chest studies →West China Hospital is the lead sponsor of 501 studies on the registry; 246 are open to participants now.
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Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
ASA physical status
The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
0.25% ropivacaine 0.5 ml/kg is injected at the fascial plane deep to the erector spinae muscle
Procedure: ESPB group
0.25% ropivacaine 0.5 ml/kg is injected into the thoracic paravertebral space (T5) using TPVB approach.
Procedure: TPVB group
A 21-gauge 100-mm needle will be inserted into the fascial layer beneath the iliocostalis, longissimus, and spinalis muscles. A bolus of 0.25% ropivacaine 0.5 ml/kg will be injected into the fascial layer. Contralateral ESPB will be performed similarly.
Also known as: Erector spinae plane block
A 21-gauge 100-mm insulated needle will be inserted into the paravertebral space via an in-plane parasagittal approach. After perforating the costotransverse ligament, 0.25% ropivacaine 0.5 ml/kg will be injected. Anterior movement of the pleura indicated the appropriate spread of the local anesthetics in the paravertebral space. The process will be repeated on the contralateral side.
Also known as: Thoracic paravertebral block
Pain scores at rest at 24 hours postoperatively
Pain scores will be recorded using the Numeric Rating Scale (NRS) scores (0-10).
Time frame: 24 hours postoperatively
The pain degree at rest and after movement or coughing(dynamic)
The pain degree at rest and after movement or coughing at 3, 6, 12, 24, and 48 hours after surgery respectively.
Time frame: at 3, 6, 12, 24, and 48 hours after surgery
total rescue morphine-equivalent consumption per weight
total rescue morphine-equivalent consumption per weight at predetermined time intervals (24 and 48 hours) after surgery
Time frame: at 24 and 48 hours after surgery
Emergence agitation at 5, 15, 30 min after extubation
Emergence agitation will be registered using pediatric anesthesia emergence delirium (PAED) at 5, 15, 30 min after extubation
Time frame: at 5, 15, 30 min after extubation
Total dosage of intraoperative sufentanil and remifentanil
Total dosage of intraoperative sufentanil and remifentanil per weight
Time frame: during surgery
The time to first analgesia request
Time from operation to first rescue analgesia request
Time frame: within the 3 days after surgery
The time to first mobilization
Time from operation to ambulation
Time frame: within the 3 days after surgery
Side effects
Side effects such as pneumothorax, local anesthetic toxicity, postoperative nausea and vomiting
Time frame: within the 5 days after surgery
Plan to share: No
This study is completed, as verified in Nov 2023. You cannot join it, but the record below documents what was studied.
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