An interventional study of ES catheter and Intercostal nerve cryoablation (INC) in Pectus Excavatum, sponsored by Children's Hospital Medical Center, Cincinnati. Recruiting at 1 site in United States. Open to participants aged 12 Years to 21 Years. Per ClinicalTrials.gov, last updated 2026-10-08.
Sponsored by Children's Hospital Medical Center, Cincinnati · Not applicable, Interventional, and Treatment
Participants will be randomized to receive ES catheter or cryoablation for pain management after the Nuss procedure. The goal of this study is to compare the following between the two groups:
Participants will receive surveys for up to 12 months postoperatively.
79 studies on the registry are indexed under Funnel Chest; 10 are open to participants now.
This study's planned enrollment of 176 is above the median of 40 across 46 interventional studies indexed under Funnel Chest.
Browse Funnel Chest studies →Children's Hospital Medical Center, Cincinnati is the lead sponsor of 673 studies on the registry; 130 are open to participants now.
Of its 57 completed or terminated interventional studies of FDA-regulated products, 31 (54%) have results posted.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
BMI (body mass index)
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Hospital procedure for ES catheters will be followed for postoperative pain.
Procedure: ES catheter
Hospital procedure for intercostal nerve cryoablation will be followed for postoperative pain.
Procedure: Intercostal nerve cryoablation (INC)
ES catheter for postoperative pain control
INC used for postoperative pain control
Compare time to reach discharge
Comparing physical therapy goals to meet discharge criteria.
Time frame: Day of surgery up tp 10 days post-operative
Opioid consumption
Comparing opioid consumption
Time frame: Day of surgery to up to one year
Numbness on chest
An exam glove with ice will used on the anterior axillary line to obtain a rating of the sensation felt. 0 - no sensation 1. \- lessened sensation 2. \- abnormal/painful sensation 3. \- no sensation
Time frame: Day of surgery and post-operative day 1
Neuropathic pain
Surveys will be used to compare the incidence of neuropathic pain
Time frame: Pre-operative, 6 weeks, 2-3 months, 4-6 months and 10-12 months post-operatively
Started Apr 2024 (actual). Primary completion is estimated for Apr 2029, 60 months after the start.
Of 31 interventional studies with no phase under Funnel Chest, half reached primary completion within 45 months of starting (the median), counting those still running; a quarter within 17 and three quarters within 68. This study's planned 60 months is above that.
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
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Children's Hospital Medical Center, Cincinnati →