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CompletedNCT05025579Updated Aug 27, 2021

What is the Effect of Aerobic Exercise on Depression in Geriatric Individuals Diagnosed With Depression?

An interventional study of Aerobic Exercise in Aerobic Exercise, Depression and Geriatric, sponsored by Ankara Yildirim Beyazıt University. Completed at 2 sites in Turkey. Open to participants aged 65 Years to 75 Years. Per ClinicalTrials.gov, last updated 2021-08-27.

Sponsored by Ankara Yildirim Beyazıt University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 2 years 4 months after the study started (first participant enrolled Apr 2019, registered Aug 2021).
Phase
Not applicable
Study type
Interventional
Enrollment
30
Allocation
Not applicable
Ages
65 Years to 75 Years
Sex
All
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Study summary

This study was planned to examine the effect of aerobic exercises on depression in geriatric individuals with a diagnosis of depression.

Read the detailed description

In this study 67 ± 5 years of age averaged and by the physician in geriatric depression diagnosis was placed 38 sedentary geriatric subjects were included. Meet the inclusion criteria geriatric individuals information, vital signs (pulse,"beats /min", blood pressure, " mmHg ", respiration number, respiratory rate,) was recorded. Depression levels, Depression Outcome Scale- KOFDSS to and quality of life is Quality of Life Survey -EUROHIS WHO-QOL) were evaluated. 6-week, 4 days a week aerobic exercise program was applied to geriatric individuals. As aerobic exercise which included the heating and cooling cycle was started the first week and 120 minutes, 160 minutes weekend out and gradually the intensity was given as an exercise program to be increasing. Individuals from the 6-week program were re-evaluated.

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Conditions studied

  • Aerobic Exercise
  • Depression
  • Geriatric
  • Chronic Illness

Keywords

  • Aerobic Exercise
  • Depression
  • Geriatric
  • Chronic Illness
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In context

Chronic Disease

990 studies on the registry are indexed under Chronic Disease; 178 are open to participants now.

This study's enrollment of 30 is below the median of 120 across 722 interventional studies indexed under Chronic Disease.

Browse Chronic Disease studies →

Lead sponsor

Ankara Yildirim Beyazıt University is the lead sponsor of 228 studies on the registry; 53 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
65 Years to 75 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • 65-75 years of age a in range, geriatric depression diagnosed with and willing to participate in the study is when individuals were included in the study.

Exclusion criteria

Exclusion Criteria:

  • Having geriatric psychiatric disorders other than depression, not being able to ride a bike for any reason, have contraindications for exercise, inability to adapt to exercise, not volunteering to participate
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Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
30 participants (actual)

Study arms

  • Experimental
    Exercise group

    Considering the protocol suggested in the literature and by examining exercise samples for geriatric individuals, an exercise protocol was created. The first week started with aerobic exercises with a total of 120 minutes, and the next week increased to 160 minutes . A 6-week exercise program was planned and applied 4 days a week in which the intensity was increased gradually. People 's heart rate, blood pressure and respiratory frequency exercise program implementation before and after was recorded in the evaluation form.

    Other: Aerobic Exercise

Interventions

  • OtherAerobic Exercise

    Since up in 2 min 10 repetitions active joint movement (while seated knee flexion and extension the ankle plantar and dorsal flexion , standing the hip flexion , extension the , abduction and adduction ) , treadmill for 3 minutes, 0.5 m / sec speed walk with and to adapt both warming bike 5 minutes, RPE ( Rating of Perceived exertion discoverable by exertion rate) will be 2/10 in a way was built. As aerobic exercise, the first week will be RPE 4/10 for 10 minutes, the second week with RPE 4/10 12 minutes, the third week with RPE 4/10 14 minutes, the fourth week with RPE 4/10, 16 minutes, the fifth week with RPE 5/ 2 0 will be as 18 minutes sixth week RPA 10.6 will form was done 20 minutes of exercise . Cooling period in the RPE 2.10 will be the 5 minute turning cycling, 5 min active range of motion exercises and stretching was done.

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What researchers measure

Primary outcomes

  1. geriatric depression

    Change from Clinically useful depression outcome scale score at beginning and 6th. weeks

    Time frame: before and after treatment (24 sessions, beginning and 6th. weeks)

Secondary outcomes

  1. Life Quality

    Change from World Health Organization Quality of Life Questionnaire (EUROHIS-QOL) score at beginning and 6th. weeks

    Time frame: before and after treatment (24 sessions, beginning and 6th. weeks)

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Study locations

2 sites
  • Ankara Yildirim Beyazit University,Faculty of Health Sciences, Physiotherapy and Rehabilitation Department
    Ankara, 06760, Turkey
  • Ankara Yildirim Beyazit University,Faculty of Health Sciences, Physiotherapy and Rehabilitation Department
    Ankara, Turkey
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References and documents

Publications

  • Blumenthal JA, Babyak MA, Moore KA, Craighead WE, Herman S, Khatri P, Waugh R, Napolitano MA, Forman LM, Appelbaum M, Doraiswamy PM, Krishnan KR. Effects of exercise training on older patients with major depression. Arch Intern Med. 1999 Oct 25;159(19):2349-56. doi: 10.1001/archinte.159.19.2349. PubMed 10547175 ↗
  • Rinaldi P, Mecocci P, Benedetti C, Ercolani S, Bregnocchi M, Menculini G, Catani M, Senin U, Cherubini A. Validation of the five-item geriatric depression scale in elderly subjects in three different settings. J Am Geriatr Soc. 2003 May;51(5):694-8. doi: 10.1034/j.1600-0579.2003.00216.x. PubMed 12752847 ↗
  • Egede LE, Nietert PJ, Zheng D. Depression and all-cause and coronary heart disease mortality among adults with and without diabetes. Diabetes Care. 2005 Jun;28(6):1339-45. doi: 10.2337/diacare.28.6.1339. PubMed 15920049 ↗
  • Lieberwirth C, Wang Z. The social environment and neurogenesis in the adult Mammalian brain. Front Hum Neurosci. 2012 May 8;6:118. doi: 10.3389/fnhum.2012.00118. eCollection 2012. PubMed 22586385 ↗
  • Babyak M, Blumenthal JA, Herman S, Khatri P, Doraiswamy M, Moore K, Craighead WE, Baldewicz TT, Krishnan KR. Exercise treatment for major depression: maintenance of therapeutic benefit at 10 months. Psychosom Med. 2000 Sep-Oct;62(5):633-8. doi: 10.1097/00006842-200009000-00006. PubMed 11020092 ↗
  • Christmas C, Andersen RA. Exercise and older patients: guidelines for the clinician. J Am Geriatr Soc. 2000 Mar;48(3):318-24. doi: 10.1111/j.1532-5415.2000.tb02654.x. PubMed 10733061 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 27, 2021, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT05025579
Lead sponsor
Ankara Yildirim Beyazıt University
Responsible party
Sponsor
First posted
Aug 27, 2021
Start date
Apr 1, 2019
Primary completion
Jun 30, 2019
Completion
Jul 30, 2019
Last update
Aug 27, 2021

Study contacts

Rabia Tugba Kilic
principal investigator · Ankara Yildirim Beyazit University,Faculty of Health Sciences, Physiotherapy and Rehabilitation Department ANKARA, Turkey, 06760
Bonny Wamukoya Wasıke
study director · Ankara Yildirim Beyazit University, Faculty of Health Sciences, Physiotherapy and Rehabilitation Department
Necmiye Un Yildirim
study chair · Ankara Health Sciences University Department of Physical Therapy and Rehabilitation

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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