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CompletedNCT04959461webCHATUpdated Mar 27, 2026Results posted

Preventing Impaired Driving Among Adolescents

An interventional study of webCHAT and Usual Care in Substance-Related Disorders, sponsored by Stanford University. Completed at 2 sites in United States. Open to participants aged 15 Years to 17 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-03-27.

Sponsored by Stanford University · Not applicable, Interventional, and Prevention

Phase
Not applicable
Study type
Interventional
Enrollment
198
Allocation
Randomized
Ages
15 Years to 17 Years
Sex
All
01

Study summary

The primary goal of this project is to evaluate the efficacy of webCHAT, a single-session web-intervention, on reducing impaired driving among adolescents receiving behind-the-wheel training at driver education programs.

Read the detailed description

Alcohol and marijuana (AM) are the most commonly used substances among adolescents in the U.S. The consequences of AM use are significantly higher relative to use of either substance alone. This study builds on effective interventions that have demonstrated reductions in alcohol and/or marijuana use and reduced consequences one year later, and proposes to adapt one of those interventions, CHAT, to the web (web-CHAT). The investigators will evaluate the efficacy of web-CHAT among 15.5-17-year-old adolescents (n=150) recruited when teen participants are attending behind-the-wheel training. The study has the potential to promote public welfare by improving adolescent health outcomes and reducing risky driving behaviors that can have substantial monetary and social costs, as well as by providing unique insight into what mediates reduced risky driving attitudes behaviors among those in the intervention. The study is innovative because it is for both youth who are at risk for substance use as well as those who are not, and it is delivered during a teachable moment when adolescents receive driver's education. Finally, this study can provide unique insights about the efficacy of web-CHAT to reduce marijuana initiation, use, and risky driving attitudes in the context of a changing marijuana policy climate. A 3-year study is proposed to test the feasibility of research procedures in a driver education setting and pilot the efficacy of web-CHAT. The investigators will test whether web-CHAT reduces alcohol and/or marijuana initiation or use compared to teens in UC, at three and six-month follow-up.

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Conditions studied

  • Substance-Related Disorders

Keywords

  • impaired driving
03

In context

Substance-Related Disorders

2,124 studies on the registry are indexed under Substance-Related Disorders; 393 are open to participants now.

This study's enrollment of 198 is above the median of 108 across 1,727 interventional studies indexed under Substance-Related Disorders.

Browse Substance-Related Disorders studies →

Lead sponsor

Stanford University is the lead sponsor of 2,117 studies on the registry; 425 are open to participants now.

Of its 259 completed or terminated interventional studies of FDA-regulated products, 197 (76%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
15 Years to 17 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • 15.5-17 year olds enrolled in driver education school
  • Access to a computer or smartphone
  • Within one month of taking their driver's licensing exam

Exclusion criteria

Exclusion Criteria:

  • Under 15.5 or over 17 years old
  • Not enrolled in one of the participating schools
  • Non-English speaking
05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
198 participants (actual)

Study arms

  • Experimental
    webCHAT

    Single session 20-40minute self-guided web program that discusses promotes healthy decision making around driving and discusses the risks of alcohol and cannabis-influenced driving.

    Behavioral: webCHAT

  • Active comparator
    Usual Care

    Existing driving school education

    Behavioral: Usual Care

Interventions

  • BehavioralwebCHAT

    A self-guided, single session web intervention that utilizes a motivational interviewing style to prevent impaired driving

  • BehavioralUsual Care

    6 hours of driver education

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What researchers measure

Primary outcomes

  1. Alcohol and/or Cannabis Use

    Total number of participants who self-reported an increased frequency of using the specified substance or substance combination in the past 3 months at 3- and/or 6-month-follow-up when compared to baseline, as denoted by a binary variable (1 = increased frequency; 0 = maintained or decreased frequency)

    Time frame: Baseline through 6-month-follow-up

Secondary outcomes

  1. Driving Under the Influence

    Number and percentage of participants who drove under the influence of alcohol and/or cannabis in the past 90 days

    Time frame: Assessed at 6 month follow-up

  2. Riding With Impaired Driver

    Total number of participants who self-reported an increased frequency of riding with an impaired driver (RWID) who had consumed the specified substance or combination of substances in the past 3 months at 3- and/or 6-month-follow-up when compared to baseline as indicated by a binary (1 = increased frequency; 0 = maintained or reduced frequency)

    Time frame: Baseline through month 6

  3. Perceived Descriptive Norms

    Percentage of their peers (0% of their peers-100% of their peers) participants believe have consumed alcohol, cannabis, or both simultaneously in past month

    Time frame: 6 month follow-up

07

Results

Posted Mar 27, 2026

Participant flow

Participant flow — Overall Study
MilestonewebCHATUsual Care
Started10692
Completed 3-month survey5855
Completed 6-month survey6457
Completed6457
Not completed4235

Outcome measures

PrimaryAlcohol and/or Cannabis Use

Total number of participants who self-reported an increased frequency of using the specified substance or substance combination in the past 3 months at 3- and/or 6-month-follow-up when compared to baseline, as denoted by a binary variable (1 = increased frequency; 0 = maintained or decreased frequency)

Time frame:
Baseline through 6-month-follow-up
Reported as:
Count of participants · Participants
Alcohol and/or Cannabis Use
ParticipantswebCHATUsual Care
Alcohol82
Cannabis72
Simultaneous Use42
Statistical analysis
  • webCHAT vs Usual Care · Regression, Logistic · p = 0.24 (The a priori threshold for statistical significance is \<= 0.05)
SecondaryDriving Under the Influence

Number and percentage of participants who drove under the influence of alcohol and/or cannabis in the past 90 days

Time frame:
Assessed at 6 month follow-up
Reported as:
Count of participants · Participants
Driving Under the Influence
ParticipantswebCHATUsual Care
Driving Under the Influence23
Statistical analysis
  • webCHAT vs Usual Care · Regression, Logistic · p = 0.63 (The a priori threshold for statistical significance is \<=0.05)
SecondaryRiding With Impaired Driver

Total number of participants who self-reported an increased frequency of riding with an impaired driver (RWID) who had consumed the specified substance or combination of substances in the past 3 months at 3- and/or 6-month-follow-up when compared to baseline as indicated by a binary (1 = increased frequency; 0 = maintained or reduced frequency)

Time frame:
Baseline through month 6
Reported as:
Count of participants · Participants
Riding With Impaired Driver
ParticipantswebCHATUsual Care
RWID-Alcohol93
RWID-Cannabis60
RWID-Simultaneous00
Statistical analysis
  • webCHAT vs Usual Care · Regression, Logistic · p = 0.12 (The a priori threshold for statistical significance is \<= 0.05) · Odds ratio (or): 2.95 · 95% CI 0.828 to 13.81
SecondaryPerceived Descriptive Norms

Percentage of their peers (0% of their peers-100% of their peers) participants believe have consumed alcohol, cannabis, or both simultaneously in past month

Time frame:
6 month follow-up
Reported as:
Mean · Percent of Peers
Perceived Descriptive Norms
Percent of PeerswebCHATUsual Care
Consume Alcohol45 ± 2155 ± 22
Consume Cannabis36 ± 2148 ± 23
Consume Simultaneously26 ± 1536 ± 21
Statistical analysis
  • webCHAT vs Usual Care · Regression, Linear · p = 0.004 (The a priori threshold for statistical significance is \<= 0.05) · Effect size: 0.624 · 95% CI 0.337 to 0.909

Adverse events

Collected over From baseline until the end of follow-up, up to 6 months. Non-serious events are listed at a 0% frequency threshold.

Adverse event summary by group
GroupDeathsSeriousOther
webCHAT0/106 (0%)0/106 (0%)0/106 (0%)
Usual Care0/92 (0%)0/92 (0%)0/92 (0%)

Baseline characteristics

Age, Categorical
Age, Categorical(Participants)webCHATUsual CareTotal
<=18 years10692198
Between 18 and 65 years000
>=65 years000
Sex/Gender, Customized
Sex/Gender, Customized(Participants)webCHATUsual CareTotal
Gender Identity — Male423779
Gender Identity — Female6454118
Gender Identity — Other011
Race (NIH/OMB)
Race (NIH/OMB)(Participants)webCHATUsual CareTotal
American Indian or Alaska Native202
Asian336
Native Hawaiian or Other Pacific Islander011
Black or African American123
White8573158
More than one race131225
Unknown or Not Reported213
Ethnicity (NIH/OMB)
Ethnicity (NIH/OMB)(Participants)webCHATUsual CareTotal
Hispanic or Latino549
Not Hispanic or Latino10188189
Unknown or Not Reported000
CRAFFT Screener
CRAFFT Screener(Participants)webCHATUsual CareTotal
>=1534699
<1534699
Lifetime Substance Use
Lifetime Substance Use(Participants)webCHATUsual CareTotal
Alcohol403171
Cannabis121729
Simultaneous Cannabis and Alcohol Use91019
No Lifetime History453479
Lifetime History of Riding with Impaired Driver
Lifetime History of Riding with Impaired Driver(Participants)webCHATUsual CareTotal
Rode with Impaired Driver333467
Did Not Ride with Impaired Driver7358131
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Study locations

2 sites
  • DriveSafe Driving School
    Denver, Colorado 80220, United States
  • DriveSafe Driving School
    Dearborn, Michigan 48126, United States
09

References and documents

Publications

  • Nameth K, Ueland E, D'Amico EJ, Osilla KC. Feasibility and acceptability of a web-intervention to prevent alcohol and cannabis-impaired driving among adolescents in driver education. Addict Sci Clin Pract. 2024 Nov 18;19(1):83. doi: 10.1186/s13722-024-00513-2. PubMed 39558402 ↗
  • Osilla KC, Nameth K, Rodriguez A, Hummer JF, D'Amico EJ. Preventing alcohol and cannabis-impaired driving among adolescents: Effects of a web-intervention in a driver education program. J Subst Use Addict Treat. 2026 Jul;186:209945. doi: 10.1016/j.josat.2026.209945. Epub 2026 Mar 17. PubMed 41850531 ↗
  • Osilla KC, D'Amico EJ, Smart R, Rodriguez A, Nameth K, Hummer J. Study design to evaluate a web-intervention to prevent alcohol and cannabis-impaired driving and use among adolescents in driver education. Addict Sci Clin Pract. 2023 Mar 24;18(1):17. doi: 10.1186/s13722-023-00373-2. PubMed 36964608 ↗

Study documents

  • Study protocol · Aug 4, 2023
  • Statistical analysis plan · Jul 15, 2025

Documents are hosted by the registry — open the source record to download them.

Individual participant data

Plan to share: No

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 27, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT04959461
Lead sponsor
Stanford University
Collaborators
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Responsible party
Karen Osilla (Associate Professor, Stanford University) — Principal investigator
First posted
Jul 13, 2021
Start date
Jan 1, 2022
Primary completion
Mar 30, 2025
Completion
Aug 31, 2025
Results posted
Mar 27, 2026
Last update
Mar 27, 2026

Study contacts

Karen Osilla, PhD
principal investigator · Professor

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Mar 2026. You cannot join it, but the record below documents what was studied.

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