CClinicalTrials.gg
CompletedNCT04899999Updated Aug 1, 2025Results posted

Graphic Messages to Prevent E-Cigarette Use Among Black and Latino Adolescents

An interventional study of Financial reward graphic message and Health reward graphic message in Vaping, sponsored by University of Rochester. Completed at 1 site in United States. Open to participants aged 12 Years to 17 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-08-01.

Sponsored by University of Rochester · Not applicable, Interventional, and Prevention

Phase
Not applicable
Study type
Interventional
Enrollment
362
Allocation
Randomized
Ages
12 Years to 17 Years
Sex
All
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Study summary

The aim of this study is to determine if graphic messages prevent future vaping use among African American and Latino adolescents. The images have been developed in a user-design model and include four main themes: health reward, financial reward, self-efficacy, and social norms. We will assess pre- and post-exposure reactions on likelihood of future vaping among African American and Latino adolescents.

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Conditions studied

  • Vaping

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In context

Vaping

160 studies on the registry are indexed under Vaping; 72 are open to participants now.

This study's enrollment of 362 is above the median of 110 across 135 interventional studies indexed under Vaping.

Browse Vaping studies →

Lead sponsor

University of Rochester is the lead sponsor of 715 studies on the registry; 116 are open to participants now.

Of its 56 completed or terminated interventional studies of FDA-regulated products, 44 (79%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
12 Years to 17 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • self-identify as African American/Black and/or Hispanic/Latino
  • know how to read and speak English and/or Spanish
  • have never used e-cigarettes
  • have access to a device that will be able to connect to the online survey

Exclusion criteria

Exclusion Criteria:

  • not identifying as African American/Black and/or Hispanic/Latino
  • using e-cigarettes
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Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
362 participants (actual)

Study arms

  • Experimental
    Financial reward graphic message

    Behavioral: Financial reward graphic message

  • Experimental
    Health reward graphic message

    Behavioral: Health reward graphic message

  • Experimental
    Self-efficacy graphic message

    Behavioral: Self-efficacy graphic message

  • Experimental
    Social norms graphic message

    Behavioral: Social norms graphic message

Interventions

  • BehavioralFinancial reward graphic message

    Graphic image will be shared with the participants online once in either English or Spanish depending on their language of preference. Image includes the following text: Vaping leads to nothing. Don't let your money vaporize away.

  • BehavioralHealth reward graphic message

    Graphic image will be shared with the participants online once in either English or Spanish depending on their language of preference. Image includes the following text: Dying for a vape? It hurts more than you know.

  • BehavioralSelf-efficacy graphic message

    Graphic image will be shared with the participants online once in either English or Spanish depending on their language of preference. Image includes the following text: Vaping companies are targeting Black and Latino teens. Your life matters. Don't let them take it away.

  • BehavioralSocial norms graphic message

    Graphic image will be shared with the participants online once in either English or Spanish depending on their language of preference. Image includes the following text: Just because vaping is common, doesn't mean it's cool. Stay woke. Don't smoke.

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What researchers measure

Primary outcomes

  1. Change in Percentage of Participants Susceptible to Future Vaping

    Susceptibility to future vaping was assessed before and after exposure to the graphic messages. Informed by prior foundational research on youth electronic cigarette use, susceptibility was measured with three items assessing curiosity, intent, and social influence. Participants were asked, "Have you ever been curious about using e-cigarettes/vaping?", "Do you think that you will use e-cigarettes/vape in the next 12 months?", and "If one of your best friends were to offer you an e-cigarette/electronic vapor product, would you use it?" (1 = "Definitely not" to 4 = "Definitely yes"). Responses were dichotomized: participants were categorized as susceptible if they answered anything other than "Definitely not" to at least one item. The percentage of susceptible participants was calculated before and after exposure; change in percentage reflects the difference.

    Time frame: baseline to post-intervention, approximately 1 day

Secondary outcomes

  1. Percentage of Participants Satisfied or Very Satisfied With the Graphic Message

    Satisfaction with the assigned vaping prevention graphic message was assessed using the item: "How satisfied are you with the image?" Responses were recorded on a 5-point Likert scale from 1 = "Extremely unsatisfied" to 5 = "Extremely satisfied." Participants selecting 5 ("Extremely satisfied") were categorized as satisfied. The percentage of satisfied participants was calculated per group. Higher percentages indicate greater satisfaction with the message.

    Time frame: Day 1

  2. Percent of Participants Who Would Recommend the Graphic Message to a Friend

    participants were asked, "Would you recommend this picture to a friend?" with response options of Yes or No. The percentage of participants who responded "Yes" was calculated per group. Higher percentages indicate greater endorsement of the message.

    Time frame: Day 1

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Results

Posted Aug 1, 2025

Participant flow

Participant flow — Overall Study
MilestoneFinancial Reward Graphic MessageHealth Reward Graphic MessageSelf-efficacy Graphic MessageSocial Norms Graphic Message
Started93889289
Completed93889289
Not completed0000

Outcome measures

PrimaryChange in Percentage of Participants Susceptible to Future Vaping

Susceptibility to future vaping was assessed before and after exposure to the graphic messages. Informed by prior foundational research on youth electronic cigarette use, susceptibility was measured with three items assessing curiosity, intent, and social influence. Participants were asked, "Have you ever been curious about using e-cigarettes/vaping?", "Do you think that you will use e-cigarettes/vape in the next 12 months?", and "If one of your best friends were to offer you an e-cigarette/electronic vapor product, would you use it?" (1 = "Definitely not" to 4 = "Definitely yes"). Responses were dichotomized: participants were categorized as susceptible if they answered anything other than "Definitely not" to at least one item. The percentage of susceptible participants was calculated before and after exposure; change in percentage reflects the difference.

Time frame:
baseline to post-intervention, approximately 1 day
Reported as:
Number · percentage of participants
Change in Percentage of Participants Susceptible to Future Vaping
percentage of participantsFinancial Reward Graphic MessageHealth Reward Graphic MessageSelf-efficacy Graphic MessageSocial Norms Graphic Message
Change in Percentage of Participants Susceptible to Future Vaping1.1-5.7-2.3-3.2
SecondaryPercentage of Participants Satisfied or Very Satisfied With the Graphic Message

Satisfaction with the assigned vaping prevention graphic message was assessed using the item: "How satisfied are you with the image?" Responses were recorded on a 5-point Likert scale from 1 = "Extremely unsatisfied" to 5 = "Extremely satisfied." Participants selecting 5 ("Extremely satisfied") were categorized as satisfied. The percentage of satisfied participants was calculated per group. Higher percentages indicate greater satisfaction with the message.

Time frame:
Day 1
Reported as:
Number · percentage of participants
Percentage of Participants Satisfied or Very Satisfied With the Graphic Message
percentage of participantsFinancial Reward Graphic MessageHealth Reward Graphic MessageSelf-efficacy Graphic MessageSocial Norms Graphic Message
Percentage of Participants Satisfied or Very Satisfied With the Graphic Message68.869.334.756.1
SecondaryPercent of Participants Who Would Recommend the Graphic Message to a Friend

participants were asked, "Would you recommend this picture to a friend?" with response options of Yes or No. The percentage of participants who responded "Yes" was calculated per group. Higher percentages indicate greater endorsement of the message.

Time frame:
Day 1
Reported as:
Number · percentage of participants
Percent of Participants Who Would Recommend the Graphic Message to a Friend
percentage of participantsFinancial Reward Graphic MessageHealth Reward Graphic MessageSelf-efficacy Graphic MessageSocial Norms Graphic Message
Percent of Participants Who Would Recommend the Graphic Message to a Friend90.394.370.680.8

Adverse events

Collected over 1 day. Non-serious events are listed at a 0% frequency threshold.

Adverse event summary by group
GroupDeathsSeriousOther
Financial Reward Graphic Message0/93 (0%)0/93 (0%)0/93 (0%)
Health Reward Graphic Message0/88 (0%)0/88 (0%)0/88 (0%)
Self-efficacy Graphic Message0/92 (0%)0/92 (0%)0/92 (0%)
Social Norms Graphic Message0/89 (0%)0/89 (0%)0/89 (0%)

Baseline characteristics

Age, Continuous
Age, Continuous(years)Financial Reward Graphic MessageHealth Reward Graphic MessageSelf-efficacy Graphic MessageSocial Norms Graphic MessageTotal
Mean15.04 ± 1.6115.06 ± 1.3515.00 ± 1.4614.89 ± 1.5215.00 ± 1.49
Sex: Female, Male
Sex: Female, Male(Participants)Financial Reward Graphic MessageHealth Reward Graphic MessageSelf-efficacy Graphic MessageSocial Norms Graphic MessageTotal
Female38342626124
Male54546562235
Race/Ethnicity, Customized
Race/Ethnicity, Customized(Participants)Financial Reward Graphic MessageHealth Reward Graphic MessageSelf-efficacy Graphic MessageSocial Norms Graphic MessageTotal
Hispanic/Latino45464644181
Black/African American48424645181
Region of Enrollment
Region of Enrollment(participants)Financial Reward Graphic MessageHealth Reward Graphic MessageSelf-efficacy Graphic MessageSocial Norms Graphic MessageTotal
United States89818688344
Puerto Rico476118
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Study locations

1 site
  • University of Rochester Medical Center
    Rochester, New York 14642, United States
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References and documents

Study documents

  • Protocol and statistical analysis plan · Jun 18, 2021
  • Informed consent form · Jun 18, 2021

Documents are hosted by the registry — open the source record to download them.

Individual participant data

Plan to share: No

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 1, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT04899999
Lead sponsor
University of Rochester
Collaborators
National Cancer Institute (NCI)
Responsible party
Francisco Cartujano, MD (Assistant Professor, University of Rochester) — Principal investigator
First posted
May 25, 2021
Start date
Aug 6, 2021
Primary completion
Dec 15, 2021
Completion
Dec 15, 2021
Results posted
Aug 1, 2025
Last update
Aug 1, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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