An interventional study of Flow with Nature in Depression, sponsored by JAMK University Of Applied Sciences. Completed at 3 sites in Finland. Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2021-07-01.
Sponsored by JAMK University Of Applied Sciences · Not applicable, Interventional, and Treatment
Among 59 studies in Depression with a site in Finland — 16 open to participants now, 25 under way, 4 of them phase 3. Depression · Finland.
Among the 59 studies in Depression with a site in Finland, this one is the 37th largest by enrollment of the 55 interventional ones that give a count, is one of 3 that started in 2019, is one of 30 with no phase, and was the 35th registered.
8,577 studies on the registry are indexed under Depression; 1,720 are open to participants now.
Browse Depression studies →16 of the 59 studies in Depression with a site in Finland are open now. Recruiting first, the newest first:
University of Helsinki · Sites in Finland
Neurocrine Biosciences · Sites in Finland, United States, Belgium and 4 more countries
Neurocrine Biosciences · Sites in Finland, United States, Australia and 20 more countries
Teppo Sarkamo · Sites in Finland
Joint Authority for Päijät-Häme Social and Health Care · Sites in Finland
A study can be open while its sites in Finland have not opened yet or have stopped. Only those recruiting at a site in Finland →
Of the 1,088 Depression studies recruiting now, 469 (43%) set no upper age limit and 519 (48%) stop at 75 or younger; 203 take children under 18; 310 take healthy volunteers.
This study: 18 Years to 65 Years · all sexes · no healthy volunteers.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
59 studies; the count open now beside each. This study's row is marked.
A study in two phases is counted once above. Listed by phase, each with its combined phases: Phase 2 8 · Phase 3 15 · Phase 4 5
First in 2004; this study’s year is marked. 3 started in 2019.
This study's enrollment of 147 is above the median of 81 across 7,063 interventional studies indexed under Depression.
Median enrollment 295 across the 55 interventional studies, 590 across the 4 observational. Of the 29 that completed or were terminated, 7 (24%) have results posted.
This tab as a report to print or save as PDF → With an account.
20 of 59 have an industry lead sponsor. The 10 most frequent:
JAMK University Of Applied Sciences is the lead sponsor of 4 studies on the registry; 1 is open to participants now.
JAMK University Of Applied Sciences has 1 study filed under Depression — fewer than ten, so there is no comparison to draw.
7 of the studies in Depression with a site in Finland that are under way reach primary completion within a year, 3 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT06922110Phase 3Xenon Pharmaceuticals Inc.An Open-Label Study of Azetukalner in Major Depressive Disorder | 2027-01 |
| NCT07076407Phase 3Xenon Pharmaceuticals Inc.A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3) | 2027-05 |
| NCT06963021Phase 3Neurocrine BiosciencesNBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD) | 2027-07 |
| NCT07868146University of Eastern FinlandPREWELL Digital Well-being Promotion Intervention With the BitHabit App | 2026-12-31 |
| NCT06633146Joint Authority for Päijät-Häme Social and Health CareStroke Rehabilitation Utilizing Therapeutical Methods Designed for Nature Environments | 2026-12-31 |
Among the 59 studies in Depression with a site in Finland, from their registry updates:
This tab as a report to print or save as PDF → With an account.
This multi-centre research investigates the effects of nature-based treatment group on participants diagnosed with depression. In total, 147 persons participated in the study in various locations in Finland. All participants received treatment as usual (TAU). They were randomised into nature-based group + TAU (n = 70) or TAU-only (n = 77). The participants in the nature-based group + TAU were offered 12 sessions once a week in addition to standard care. The measurement points included pre-treatment measurement at the baseline and post-treatment measurement at the end of the intervention, which was 12 weeks after the pre-treatment measurement. The follow-up measurement was 3 months after the post-treatment measurement. The effects of the intervention were assessed with a clinical measure of depression (BDI-I) and with indicators of psychological distress (CORE-10), subjective well-being (SWEMWBS), work/study ability (WAI) and nature experiences (ROS, KOLU). The participants in the treatment group (nature-based group +TAU) were compared to the participants in the control group who received TAU-only.
This research investigates the outcomes of nature-based treatment groups in the treatment of adults with depression. In total, 147 participants were involved. Of them, 70 were randomized into DMT group and 77 into the control group. All participants received treatment as usual during the research. The inclusion criteria of the study were: a diagnoses of depression (ICD -diagnostic system), BDI-I score 10 or above (cut off score for mild depression), treatment contact in a health care service and 18-65 years of age. The exclusion criteria were: 1) active suicidal ideation, 2) psychotic symptoms, and 3) substance misuse that is on a critical level (Audit questionnaire scores above 10). Also, participants who had pain-related problems that restricted daily life or were pregnant were not admitted to the study.
Nature-based treatment group was facilitated by a health care professional and included 12 x 90 mins sessions within 12 weeks. Depressive symptoms (BDI-I), psychological distress (CORE-10), subjective well-being (SWEMWBS), ability to work/study (WAI), and nature experiences (ROS, KOLU) were assessed at three measurement points: pre-measurement at the baseline, post-measurement 12 weeks after the pre-treatment measurement, and a follow-up measurement three months after the post-treatment measurement.
This research includes a larger number of participants (N = 147) than have been involved in previous studies utilising randomised controlled trials in nature-based interventions. The research generates further information about the effectiveness of nature-based therapy groups in the rehabilitation of depression as it was conducted in five cities across Finland. This type of multi-centre research can provide a realistic picture of the typical practice of a range of health care professionals working with participants in various geographic locations.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
The participants in the treatment group were offered 12 nature-based group therapy sessions in addition to standard care.
Behavioral: Flow with Nature
The participants in the control group continued treatment as usual in the health care services.
Nature-based intervention was facilitated by a health care professional and included 12 x 90 mins sessions within 12 weeks.
Change from baseline depressive symptoms (Beck Depression Inventory; BDI-I) at 12-week post-treatment measurement.
BDI-I (Beck Depression Inventory - I) measures depressive symptoms with 21 items. Each item is scored 0-3 and sum scores are calculated on the basis of participants' responses. The total sum score can range from 0 to 63 and higher score indicates higher depression.
Time frame: 12 weeks
Change from post-treatment depressive symptoms (Beck Depression Inventory-I; BDI-I) at three-month follow-up measurement.
The change in depressive symptoms between the post-treatment measurement at the end of the 12-week intervention and the 3-month follow-up. BDI-I (Beck Depression Inventory - I) measures depressive symptoms with 21 items. Each item is scored 0-3 and sum scores are calculated on the basis of participants' responses. The total sum score can range from 0 to 63 and higher score indicates higher depression.
Time frame: 3 months
Plan to share: No
Ran from Jan 2019 to primary completion in Mar 2021, 26 months.
Of 3,468 non-industry interventional studies with no phase under Depression, half reached primary completion within 21 months of starting (the median), counting those still running; a quarter within 10 and three quarters within 41. This study's 26 months is above that.
Counting every sponsor, half of 3,566 studies reached it within 21 months; a quarter within 9 and three quarters within 41.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Jun 2021. You cannot join it, but the record below documents what was studied.
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JAMK University Of Applied Sciences