An interventional study of Transcranial Direct Current Stimulation in Cognitive Symptom and Healthy, sponsored by Medipol University. Completed at 2 sites in Turkey. Open to participants aged 18 Years to 30 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2021-05-05.
Sponsored by Medipol University · Not applicable, Interventional, and Diagnostic
Background: Transcranial direct current stimulation(tDCS) has been used to improve cognitive functions in healthy young adults.
Purpose: To investigate the effect of TDCS application on different cortex regions on cognitive function.
Methods: Sixty individuals aged 18-30 were included in the study. The participants were randomly divided into the left dorsolateral prefrontal cortex (Left DLPFC Group)(n=20), the right posterior parietal cortex (Right PPC Group)(n=20), and the sham group (Sham Group)(n=20). tDCS was applied for 20 minutes on weekdays for 2 weeks. The participants were evaluated in terms of cognitive functions with Neuropsychometric Test Battery before and after treatment.
111 studies on the registry are indexed under Neurobehavioral Manifestations; 28 are open to participants now.
This study's enrollment of 57 is below the median of 71 across 84 interventional studies indexed under Neurobehavioral Manifestations.
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Exclusion Criteria:
The anode electrode of tDCS was applied to the left DLPFC and the cathode electrode was connected to the contralateral shoulder.
Other: Transcranial Direct Current Stimulation
The anode electrode of tDCS was applied to the right PPC and the cathode electrode was connected to the contralateral shoulder.
Other: Transcranial Direct Current Stimulation
Placebo was applied by placing the electrodes in the right PPC and left DLPFC without applying current.
Other: Transcranial Direct Current Stimulation
The intervention protocols were applied using tDCS (Teknofil TESsaNova). All individuals received 2 mA of anodal tDCS for 2 weeks on weekdays. All applications were done in the form of 20-minute sessions.
Neuropsychiatric Test Battery
It is a test battery for getting detailed information about general cognitive status.
Time frame: 3 weeks
Beck Depression Scale
It measures the symptoms seen in depression such as emotional, cognitive and motivational. It includes 21 items determine a behavioral feature related to depression. Items are numbered from 0 to 3. The goal is to objectively break down the degree of symptoms. The total score of all answers is calculated as follows: 0 to 9 points: Minimally depressive symptoms 10 to 16 points: Mild depressive symptoms Between 17 and 29 points: Moderate depressive symptoms Between 30 and 63 points: Severe depressive symptoms
Time frame: 3 weeks
This study is completed, as verified in May 2021. You cannot join it, but the record below documents what was studied.
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Medipol University