An observational study in Infection, Mediastinitis and Neck Abscess, sponsored by Clinical Center of Vojvodina. Completed. Per ClinicalTrials.gov, last updated 2021-04-29.
Sponsored by Clinical Center of Vojvodina · Observational
Descending necrotizing mediastinitis (DNM) is the most serious complication of deep neck infections (DNI) with high mortality. The objective of this retrospective study was to evaluate possible prognostic factors for DNM development in deep space neck infections.
Descending necrotizing mediastinitis (DNM) is the most serious complication of deep neck infections (DNI) with high mortality. The objective of this retrospective study was to evaluate possible prognostic factors for DNM development in deep space neck infections. The study enrolled patients admitted to the Emergency Center of Vojvodina with the diagnosis of multispace DNI with or without DNM either as the primary diagnosis or with discharged diagnosis after surgical treatment during 7-years period. The data were obtained from patient medical records.
2,093 studies on the registry are indexed under Infections; 364 are open to participants now.
This study's enrollment of 289 is close to the median of 300 across 685 observational studies indexed under Infections.
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This study enrolled patients admitted to the Emergency Center of Vojvodina with the diagnosis of multispace DNI with or without DNM either as the primary diagnosis or with discharged diagnosis after surgical treatment.
The diagnosis of DNM was based on standard Estrera et al. diagnostic criteria. Cases included in the study comprised patients admitted to the hospital due to DNI affecting two or more spaces with or without DNM. Cases were excluded from the study if complete medical data could not be obtained from medical charts.
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Exclusion Criteria:
patients with infection of two or more deep neck spaces (DNI group)
Other: treatment of infection
patients with infection of two or more deep neck spaces with secondary descending necrotizing mediastinitis (DNI + DNM group)
Other: treatment of infection
Incidence of mediastinitis
Neck and chest computed tomography (CT)
Time frame: Within 6 hours of admission
Microbiological findings in DNI and DNM
Prevalence of microorganisms in mediastinitis
Time frame: Within 1 week of admission
Average number of hospital days
Comparison of average number of hospital days in DNI and DNM
Time frame: Through study completion, an average of one month
Incidence of complications
Complications among DNI and DNI+DNM groups
Time frame: Within 30 days from admission
Number of infected deep neck spaces
Neck and chest computed tomography (CT)
Time frame: Within 6 hours of admission
No study locations are listed for this record.
Plan to share: Undecided
Ran from Jan 2014 to primary completion in Dec 2020, 83 months.
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This study is completed, as verified in Apr 2021. You cannot join it, but the record below documents what was studied.
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Clinical Center of Vojvodina