CClinicalTrials.gg
CompletedNCT04864678Updated Jan 28, 2022

Vaccination Coverage and Uptake in Young People Experiencing or at Risk of Homelessness

An observational study in Homeless Youth, sponsored by Murdoch Childrens Research Institute. Completed at 1 site in Australia. Open to participants aged 15 Years to 24 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-01-28.

Sponsored by Murdoch Childrens Research Institute · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
400
Ages
15 Years to 24 Years
Sex
All
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Study summary

This retrospective audit will investigate if young people who are homeless or at risk of homelessness in Melbourne were up-to-date with routine childhood and adolescent vaccines on first encounter with a nurse-led primary health clinic (the Young People's Health Service), and if they commenced and completed immunisation catch-up plans following referral to the Young People's Health Service immunisation nurse.

The purpose of the proposed study is to establish baseline immunisation coverage within the targeted population, then to explore the impact of an immunisation nurse role on immunisation coverage in a population of young people aged 15-24 years who are experiencing or at risk of homelessness.

The Young People's Health Service is a program of the Royal Children's Hospital Department of Adolescent Medicine. The data collected will be sourced solely from the Royal Children's Hospital Electronic Medical Records.

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Conditions studied

  • Homeless Youth

Keywords

  • homeless youth
  • vaccination
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In context

Lead sponsor

Murdoch Childrens Research Institute is the lead sponsor of 96 studies on the registry; 34 are open to participants now.

Of its 5 completed or terminated interventional studies of FDA-regulated products, 3 (60%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
15 Years to 24 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Probability sample

Study population

Young people aged 15-24 years of all genders who have been referred to the Young People's Health Service immunisation nurse will be included. They have accessed a homeless youth service, refuge, or flexible learning centre in Melbourne, Australia. The study will include those who were referred between 19th February 2019 to 19th July 2020.

Inclusion criteria

  • Is between the ages of 15-24 years inclusive at enrolment
  • Has a signed general consent/referral form to the Young People's Health Service immunisation nurse between 19th February 2019 - 19th July 2020 and scanned into their EMR. Verbal consent is accepted.
  • Was referred from a clinic or outreach location attended by the Young People's Health Service (i.e. a service for people experiencing homelessness)

Exclusion criteria

Exclusion Criteria:

  • Does not have a signed consent/referral form to Young People's Health Service immunisation nurse
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Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
400 participants (actual)
Patient registry
No

Groups and cohorts

  • Young people who are experiencing or at risk of homelessness

    Young people aged 15-24 years who have accessed a homeless youth service, refuge, or flexible learning center in Melbourne, Australia.

    Other: Referral to the Young People's Health Service immunisation nurse

Interventions

  • OtherReferral to the Young People's Health Service immunisation nurse

    Young people who have been referred to an immunisation nurse at the Young People's Health Service.

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What researchers measure

Primary outcomes

  1. Proportion of participants referred to the Young People's Health Service immunisation nurse who were up-to-date for their age for vaccines on both the National Immunisation Program and the Victorian State Government Schedule.

    Young people who meet eligibility criteria will be considered up-to-date on referral if their immunisation history statement at the time of referral meets the criteria to be considered up to date as detailed in Appendix II in the Study Protocol. The percentage of the young people in the population who are up-to-date for their age with each vaccine will be described.

    Time frame: Participants who were referred to the Young People's Health Service between the study time period (Between 19th February 2019 - 19th May 2021)

  2. Proportion of participants referred to the Young People's Health Service immunisation nurse who were are at increased risk of vaccine-preventable diseases.

    Where available, data collected from the Electronic Medical Records (EMR) will include risk factors for vaccine-preventable diseases and relevant social determinants of health based on the Australian Institute of Health and Welfare, the Australian Government Department of Health and the National Centre for Immunisation Research and Surveillance publications. Participants will be considered at increased risk of vaccine-preventable diseases if the EMR includes documentation of at least one of: a history of identifying as Aboriginal or Torres Strait Islander, of arriving in Australia as a migrant, refugee or asylum seeker, of incarceration, of men who have sex with men, of alcohol or other drug misuse, of smoking cigarettes, of living with Hepatitis C or HIV, of out of home care, of being a young parent, of having non-professional tattoos, or of sex work.

    Time frame: All available medical records for the participant on the Royal Children's Hospital Electronic Medical Records regardless of time frame

Secondary outcomes

  1. Proportion of participants referred to the Young People's Health Service immunisation nurse who commence a vaccine catch-up plan.

    Electronic medical records will be reviewed to record the percentage of participants who were not up-to-date with scheduled vaccines for their age on referral, and commenced a vaccine catch-up plan following referral to an immunisation nurse at the Young People's Health Service. Vaccines required to complete a vaccine catch-up plan will depend on the age of the participant and will be determined by an immunisation nurse. A participant will be considered to have commenced an immunisation catch-up plan if they receive at least one immunisation on the plan.

    Time frame: Between 19th February 2019 - 19th May 2021

  2. Proportion of participants referred to the Young People's Health Service immunisation nurse who complete a vaccine catch-up plan.

    Electronic medical records will be reviewed to record the percentage of participants who were not up-to-date with scheduled vaccines for their age, and completed a vaccine catch-up plan following an encounter with an immunisation nurse at the Young People's Health Service. Vaccines required to complete a vaccine catch-up plan will depend on the age of the participant and will be determined by an immunisation nurse. A participant will be considered to have completed an immunisation catch-up plan if they receive all immunisations on the plan.

    Time frame: Between 19th February 2019 - 19th May 2021

  3. Mean number of follow-up contact attempts (all types) sent to young people attending the Young People's Health Service per immunisation visit.

    The mean number of contact attempts sent by staff of the Young People's Health Service to young people who require immunisation catch-up visits. Contact attempts include SMS, email, phone call, in person reminder, and letter.

    Time frame: Between 19th February 2019 - 19th May 2021

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Study locations

1 site
  • The Royal Children's Hospital Melbourne
    Parkville, Victoria 3052, Australia
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References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 28, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT04864678
Lead sponsor
Murdoch Childrens Research Institute
Collaborators
RCH League of Former Trainees and Associates Inc, Royal Children's Hospital
Responsible party
Sponsor
First posted
Apr 29, 2021
Start date
May 21, 2021
Primary completion
Nov 17, 2021
Completion
Dec 9, 2021
Last update
Jan 28, 2022

Study contacts

Belinda L Tominc, MNSc
principal investigator · Royal Children's Hospital

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jan 2022. You cannot join it, but the record below documents what was studied.

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