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CompletedNCT04862637Updated Nov 19, 2025

Detecting the Changes of Swallowing Function in Oral Cancer Patients

An observational study in Swallowing Function, sponsored by National Taiwan University Hospital. Completed at 1 site in Taiwan. Open to participants aged 20 Years to 80 Years. Per ClinicalTrials.gov, last updated 2025-11-19.

Sponsored by National Taiwan University Hospital · Observational

Study type
Observational
Model
Case-control
Time perspective
Cross-sectional
Enrollment
48
Ages
20 Years to 80 Years
Sex
All
01

Study summary

The evidence of swallowing changes in oral cancer patients is still limited. This study aimed to investigated the swallowing changes in these patients by using the videofluoroscopy (VFSS) and high resolution impedance manometry (HRIM).

Read the detailed description

Objective: to investigated the swallowing changes in oral cancer patients by using the videofluoroscopy (VFSS) and high resolution impedance manometry (HRIM).

Methods: 1. patients are fulfilled tongue cancer diagnosis; 2.they will undergo VFSS and HRIM examinations before or after surgery if they experience discomfort while swallowing.

02

Conditions studied

  • Swallowing Function

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Keywords

  • dysphagia
  • swallowing
03

In context

Deglutition Disorders

710 studies on the registry are indexed under Deglutition Disorders; 219 are open to participants now.

This study's enrollment of 48 is below the median of 97 across 207 observational studies indexed under Deglutition Disorders.

Browse Deglutition Disorders studies →

Lead sponsor

National Taiwan University Hospital is the lead sponsor of 2,563 studies on the registry; 569 are open to participants now.

Of its 11 completed or terminated interventional studies of FDA-regulated products, 2 (18%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

patients with the diagnosis of oral cancer

Inclusion criteria

  • patients elective received oral cancer surgery

Exclusion criteria

Exclusion Criteria:

  • 1. patients had major underlying disease, ex: heart, brain, lung, liver disease
  • 2. coagulopathy
  • 3.pregnancy
  • 4. the patients could not have good compliance
05

Study design

Observational model
Case-control
Time perspective
Cross-sectional
Enrollment
48 participants (actual)
Target follow-up
1 Day
Patient registry
Yes
06

What researchers measure

Primary outcomes

  1. Bolus presence time

    Lower value indicates shorter bolus presence in the pharynx

    Time frame: 15 minutes during the examination

07

Study locations

1 site
  • National Taiwan University Hospital
    Taipei, Taiwan 100, Taiwan
08

References and documents

Individual participant data

Plan to share: No — ethical concerns

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 19, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT04862637
Lead sponsor
National Taiwan University Hospital
Responsible party
Sponsor
First posted
Apr 28, 2021
Start date
Sep 15, 2022
Primary completion
Jun 10, 2025
Completion
Jun 11, 2025
Last update
Nov 19, 2025

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Sep 2025. You cannot join it, but the record below documents what was studied.

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