An interventional study of exercise in Multiple Sclerosis and Exercise, sponsored by Sanko University. Completed at 1 site in Turkey (Türkiye). Open to participants aged 18 Years to 50 Years. Per ClinicalTrials.gov, last updated 2022-01-13.
Sponsored by Sanko University · Not applicable, Interventional, and Treatment
Selective exercise programs specific to muscle groups, with the workload to be done in line with the muscle's own structure, can enable more strength to be released with less fatigue in MS, and this increase in strength can increase balance and functional activities. to determine the effects of type training (selective exercise training), eccentric and concentric training on function, balance, fatigue and muscle architecture.
Recovery and enhancement of muscle function in MS is one of the main goals in physiotherapy and rehabilitation. In literature studies, it is stated that eccentric and concentric exercises are effective exercise approaches in increasing strength and reducing fatigue. However, the best exercise method is not yet clear in terms of providing better performance adaptation with less fatigue. Considering the architectural features of the lower extremity muscles, it is aimed to increase the angle of pennation with programs that include concentric strengthening of the quadriceps, gastro-soleus and gastrocnemius muscles, which are suitable muscle groups to produce large forces by design. With programs that include eccentric strengthening of the hamstring and tibialis anterior muscles that function in a wide range of motion and have high excursion ability, it is aimed to increase fiber length.
3,525 studies on the registry are indexed under Multiple Sclerosis; 668 are open to participants now.
This study's enrollment of 33 is below the median of 50 across 2,386 interventional studies indexed under Multiple Sclerosis.
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Exclusion Criteria:
patients who do not agree to volunteer
selective training on lower extremity for 3 days/week
Other: exercise
downhill walking training on the treadmill for 2 days/week
Other: exercise
uphill walking training on the treadmill for 2 days/week
Other: exercise
exercise training for 8 weeks
muscle architecture parameter 1
The pennation angle were evaluated with Ultrasound
Time frame: Change from Baseline at 8th weeks and 12th weeks
muscle architecture parameter 2
The fiber length were evaluated with Ultrasound
Time frame: Change from Baseline at 8th weeks and 12th weeks
muscle architecture parameter 3
The muscle thickness were evaluated with Ultrasound
Time frame: Change from Baseline at 8th weeks and 12th weeks
Muscle strength
low extremity muscles were evaluated with hand dynamometer
Time frame: Change from Baseline at 8th weeks and 12th weeks
walking fatigue
Walking Fatigue Index
Time frame: Change from Baseline at 8th weeks and 12th weeks
perceived fatigue
Fatigue Severity Scale
Time frame: Change from Baseline at 8th weeks and 12th weeks
physical fatigue
Modified Borg Scale before and after 6-minute walking test
Time frame: Change from Baseline at 8th weeks and 12th weeks
static balance
Single standing tests
Time frame: Change from Baseline at 8th weeks and 12th weeks
dynamic balance
4 square step tests
Time frame: Change from Baseline at 8th weeks and 12th weeks
Functional activities 1
timed-up go test
Time frame: Change from Baseline at 8th weeks and 12th weeks
Functional activities 2
2-minute walk test
Time frame: Change from Baseline at 8th weeks and 12th weeks
Functional activities 3
25-feet walk test
Time frame: Change from Baseline at 8th weeks and 12th weeks
This study is completed, as verified in Dec 2021. You cannot join it, but the record below documents what was studied.
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