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CompletedNCT04848415OCCLUSUpdated Jun 25, 2026

Diagnostic Performance of Point of Care Ultrasound to Identify Intestinal Obstruction

An observational study in Bowel Obstruction, sponsored by Nantes University Hospital. Completed at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-06-25.

Sponsored by Nantes University Hospital · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
150
Ages
18 Years and older
Sex
All
01

Study summary

As reported in previous studies, Point-of-Care Ultrasound (POCUS) has good performance for the diagnosis of bowel obstruction even when compared with CT. This inexpensive, radiation-free tool is available in a majority of ED. It is performed at the patient's bedside with immediate results. The learning curve allows Emergency Physicians (EP) to perform this exam after a relative brief training period.

The investigators aim to investigate the ability of POCUS performed before CT to exclude the diagnosis of bowel obstruction in patients admitted for abdominal pain.

Read the detailed description

Bowel obstruction (BO) is frequently suspected in the Emergency Department (ED). Computed Tomography (CT) is commonly used to diagnose this disease. However, CT is not always available in real-time, requires technician times, is associated with increased cost and exposes patients to radiations.

The researchers will investigate the diagnosis performances of POCUS for the diagnosis of BO with comparison with CT which will be considered as the gold standard. The wain objective will be the ability to exclude the diagnosis of BO, the main criteria being the negative predictive value. The secondary objectives will be the diagnosis performances (sensitivity, specificity, positive predictive value), duration and difficulty of POCUS

02

Conditions studied

  • Bowel Obstruction

Keywords

  • Bowel obstruction
  • Computed tomography
  • Ultrasound
03

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Adult patients admitted to the ED for abdominal pain and suspicion of bowel obstruction

Inclusion criteria

  • Adult patients
  • Abdominal pain
  • Suspected bowel obstruction

Exclusion criteria

Exclusion Criteria :

- Documented end-of-life precluding CT realization

04

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
150 participants (actual)
Patient registry
No

Interventions

  • OtherPoint-of-Care Ultrasound

    Patients admitted to the ED with abdominal pain and suspicion of bowel obstruction : realization of a Point-of-Care Ultrasound after clinical exam by the Emergency Physician in charge as a standard of care. Beside usual findings, the investigators will search for signs of bowel obstruction: dilated and incompressible small bowel loop, back-and-forth peristalsis sign. Determination of probability of small bowel obstruction. Realization of a computed tomography in search of small bowel obstruction.

05

What researchers measure

Primary outcomes

  1. Negative predictive value of POCUS

    Negative predictive value of POCUS for the diagnosis of bowel obstruction compared with computed tomography result

    Time frame: Through ED stay, up to 24 hours

Secondary outcomes

  1. Positive predictive value of POCUS for the diagnosis of bowel obstruction

    Positive predictive value

    Time frame: Through ED stay, up to 24 hours

  2. Sensitivity of POCUS for the diagnosis of bowel obstruction

    sensitivity of POCUS, for the diagnosis of bowel obstruction compared with computed tomography result

    Time frame: Through ED stay, up to 24 hours

  3. Specificity of POCUS for the diagnosis of bowel obstruction

    specificity of POCUS, for the diagnosis of bowel obstruction compared with computed tomography result

    Time frame: Through ED stay, up to 24 hours

06

Study locations

1 site
  • CHU de Nantes
    Nantes, 44093, France
07

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT04848415
Lead sponsor
Nantes University Hospital
Responsible party
Sponsor
First posted
Apr 19, 2021
Start date
May 1, 2021
Primary completion
May 1, 2022
Completion
Sep 1, 2022
Last update
Jun 25, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Jun 2026. You cannot join it, but the record below documents what was studied.

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