CClinicalTrials.gg
RecruitingNCT04838171Updated Jan 21, 2026

Prospective Study of White Blood Cells

An observational study in Autoimmune Diseases, Inflammation and Rejection; Transplant, Liver, sponsored by Quell Therapeutics Limited. Recruiting at 1 site in United Kingdom. Per ClinicalTrials.gov, last updated 2026-01-21.

Sponsored by Quell Therapeutics Limited · Observational

From the registry’s dates

  • Started Mar 2021; still recruiting 5 years 6 months later.
Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
10
Sex
All
01

Study summary

The purpose of this study is to investigate white blood cells from volunteering donors to support the development of engineered regulatory T cell therapies.

02

Conditions studied

  • Autoimmune Diseases
  • Inflammation
  • Rejection; Transplant, Liver
03

In context

Autoimmune Diseases

655 studies on the registry are indexed under Autoimmune Diseases; 275 are open to participants now.

This study's planned enrollment of 10 is below the median of 300 across 208 observational studies indexed under Autoimmune Diseases.

Browse Autoimmune Diseases studies →

Lead sponsor

Quell Therapeutics Limited is the lead sponsor of 3 studies on the registry; 2 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Volunteers willing to provide white blood cells for research.

Eligibility criteria

No additional inclusion/ exclusion criteria will be applied by Quell other than those specified by the consenting institutions.

05

Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
10 participants (estimated)
Patient registry
No

Groups and cohorts

  • Specimen collection to support development of engineering Treg

    Other: White blood cell and blood collection

Interventions

  • OtherWhite blood cell and blood collection

    Mononucleocytes will be collected via apheresis

06

What researchers measure

Primary outcomes

  1. WBC characterisation to support the development of engineered regulatory T cells.

    number, type and function of white blood cells in healthy controls and in patients

    Time frame: 5 years

07

Study locations

1 of 1 sites recruiting
  • Quell Investigator Site 01
    London, United Kingdom
    Recruiting
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 21, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT04838171
Lead sponsor
Quell Therapeutics Limited
Responsible party
Sponsor
First posted
Apr 8, 2021
Start date
Mar 24, 2021
Primary completion
Dec 31, 2029 (estimated)
Completion
Jan 2030 (estimated)
Last update
Jan 21, 2026

Study contacts

Gareth Wright
Contact
contact@quell-tx.com
+4(0)2070969012

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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