CClinicalTrials.gg
CompletedNCT04799600Updated Jul 27, 2021

The Effect of the Severity of COVID-19 Disease on the Incidence of Acute Renal Failure in ICU

An observational study in COVID19 and Acute Renal Failure, sponsored by Ankara City Hospital Bilkent. Completed at 1 site in Turkey. Per ClinicalTrials.gov, last updated 2021-07-27.

Sponsored by Ankara City Hospital Bilkent · Observational

Study type
Observational
Model
Cohort
Time perspective
Cross-sectional
Enrollment
158
Sex
All
01

Study summary

Aim of the study is to determinate the frequency of acute renal failure in COVID-19 patients, its relationship with the severity of COVID-19 disease in ICU, and the ability to take precautions against these factors.

02

Conditions studied

  • COVID19
  • Acute Renal Failure

Keywords

  • COVID19
  • Acute Renal Failure
03

In context

COVID-19

7,638 studies on the registry are indexed under COVID-19; 488 are open to participants now.

This study's enrollment of 158 is below the median of 260 across 3,135 observational studies indexed under COVID-19.

Browse COVID-19 studies →

Lead sponsor

Ankara City Hospital Bilkent is the lead sponsor of 424 studies on the registry; 105 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Probability sample

Study population

Patients hospitalized in the intensive care unit diagnosed with COVID-19 will participate in the study.

Inclusion criteria

Patients hospitalized in the intensive care unit diagnosed with COVID-19 will include in the study.

Exclusion criteria

Exclusion Criteria:

there is no exclusion criteria

05

Study design

Observational model
Cohort
Time perspective
Cross-sectional
Enrollment
158 participants (actual)
Patient registry
No

Groups and cohorts

  • Acute Renal Failure in ICU

    COVID-19 Patients with Acute Renal Failure in ICU

    Other: BRESCİA-COVİD Respiratory Severity Scale

Interventions

  • OtherBRESCİA-COVİD Respiratory Severity Scale

    KDIGO acute renal failure score BRESCİA-COVID Respiratory Severity Score

06

What researchers measure

Primary outcomes

  1. KDIGO criteria

    KDIGO Criteria stage 1: Increase in SCr by ≥ 0.3 mg/dL within 48 hours or increase in SCr 1.5 to 1.9 times baseline which is known or presumed to have occurred within the prior 7 days Stage 2: 2.0 to 2.9 multiplied by baseline SCr; Stage 3: 3.0 or more multiplied by baseline; increase in SCr ≥ 4.0 mg/dL; or beginning of renal replacement therapy regardless of a previous KDIGO stage.

    Time frame: 6 months

  2. BRESCIA-COVID RESPIRATORY SEVERITY SCALE (BCRSS) scores

    The BCRSS score (between level 0-8) is calculated from "www.mdcalc.com/brescia-covid-respiratory-severity-scale-bcrss-algorithm" according to the severity of COVID disease , respiratory rate, PaO2 level, chest x-ray, and clinical status.

    Time frame: 6 months

07

Study locations

1 site
  • Ankara City Hospital
    Ankara, 06800, Turkey
08

References and documents

Publications

  • Kellum JA, Lameire N; KDIGO AKI Guideline Work Group. Diagnosis, evaluation, and management of acute kidney injury: a KDIGO summary (Part 1). Crit Care. 2013 Feb 4;17(1):204. doi: 10.1186/cc11454. PubMed 23394211 ↗
  • Wang L, Li X, Chen H, Yan S, Li D, Li Y, Gong Z. Coronavirus Disease 19 Infection Does Not Result in Acute Kidney Injury: An Analysis of 116 Hospitalized Patients from Wuhan, China. Am J Nephrol. 2020;51(5):343-348. doi: 10.1159/000507471. Epub 2020 Mar 31. PubMed 32229732 ↗
  • Rodriguez-Nava G, Yanez-Bello MA, Trelles-Garcia DP, Chung CW, Friedman HJ, Hines DW. Performance of the quick COVID-19 severity index and the Brescia-COVID respiratory severity scale in hospitalized patients with COVID-19 in a community hospital setting. Int J Infect Dis. 2021 Jan;102:571-576. doi: 10.1016/j.ijid.2020.11.003. Epub 2020 Nov 9. PubMed 33181332 ↗

Individual participant data

Plan to share: Undecided

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 27, 2021, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT04799600
Lead sponsor
Ankara City Hospital Bilkent
Responsible party
ismail aytaç (medical doctor, Ankara City Hospital Bilkent) — Principal investigator
First posted
Mar 16, 2021
Start date
Sep 1, 2020
Primary completion
Jun 15, 2021
Completion
Jul 1, 2021
Last update
Jul 27, 2021

Study contacts

betül aytaç, MD
principal investigator · ankara ch bilkent

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jul 2021. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion