An interventional study of Fructose and Glucose in Intestinal Permeability and Immune Response, sponsored by University of Vienna. Recruiting at 1 site in Austria. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-08-11.
Sponsored by University of Vienna · Not applicable, Interventional, and Basic science
The aim of the present study is to investigate the effect of fructose consumption on health parameters and the intestinal barrier in healthy individuals
University of Vienna is the lead sponsor of 49 studies on the registry; 16 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Chronic obstructive pulmonary disease: long-term lung disease that makes it hard to breathe out, including emphysema and chronic bronchitis.
BMI (body mass index)
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
COPD
Chronic obstructive pulmonary disease: long-term lung disease that makes it hard to breathe out, including emphysema and chronic bronchitis.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Following a standardization of their nutritional intake for three days, participants will receive a drink supplemented with free fructose.
Other: Fructose
Following a standardization of their nutritional intake for three days, participants will receive a drink supplemented with free glucose.
Other: Glucose
Following a standardization of their nutritional intake for three days, participants will either receive a drink supplemented with low doses of free fructose (5%).
Also known as: Diet
Following a standardization of their nutritional intake for three days, participants will either receive a drink supplemented with low doses of free glucose (5 %).
Also known as: Diet
Changes in markers of intestinal permeability
Changes in concentrations of bacterial endotoxin in blood plasma
Time frame: At the end of the treatment (1 month)
Cytokine release from blood immune cells stimulated with bacterial toxins
Changes in cytokine concentration in supernatant of immune cells before and after the treatments
Time frame: At the end of the treatment (1 month)
Started Apr 2026 (actual). Primary completion is estimated for Jul 2027, 15 months after the start.
How these figures are worked out, and which studies are left out of them.
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University of Vienna