An interventional study of Sit to stand test in SARS-CoV Infection, sponsored by University Hospital, Rouen. Terminated at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-01-22.
Sponsored by University Hospital, Rouen · Not applicable, Interventional, and Screening
As part of the Coronavirus Infectious Disease 2019 (COVID19) pandemic, the hospital care system is facing a major strain. Patients with SARS-Cov2 (severe acute respiratory syndrome coronavirus 2 ) infection can worsen very quickly, possibly presenting, within hours, severe respiratory failure requiring urgent specialized care. Therefore, it is essential to develop emergency assessment tools to assess relevant criteria to decide which patients must be kept under hospital monitoring and which patients can be treated on outpatient care.
The aim of this study is to assess the efficacy of STST in the decision to hospitalize patients consulting emergency department for a SARS-Cov2 infection. The investigators wish to show that the addition of this test to the usual hospitalization criteria reduces the proportion of patients hospitalized 48 hours after their first visit to the emergency department.
382 studies on the registry are indexed under Severe Acute Respiratory Syndrome; 14 are open to participants now.
This study's enrollment of 54 is below the median of 150 across 213 interventional studies indexed under Severe Acute Respiratory Syndrome.
Browse Severe Acute Respiratory Syndrome studies →University Hospital, Rouen is the lead sponsor of 410 studies on the registry; 104 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
For the patients enrolled in this conventional arm, the decision of hospitalisation or discharge will be taken with usual criteria (pulsed oxygen saturation (SpO2) in room air \<92% and respiratory rate\> 22/min, respiratory rate\> 30/min, Blood gas hypoxemia, decompensation of comorbidity, home monitoring not possible, other intercurrent pathology requiring hospitalization, several risk factors for COVID infection requiring hospitalization in intensive care (age\> 65y, hypertension complicated by a cardiovascular event, chronic cardiovascular disease, unbalanced diabetes with complications, chronic respiratory disease (excluding well-controlled asthma), chronic renal failure dialysis, obesity, progressive cancer under treatment, congenital or acquired immunosuppression)
For the patients enrolled in this interventional arm, the decision of hospitalisation or discharge will be taken with usual criteria and the result of Sit to Stand Test.
Diagnostic Test: Sit to stand test
The sit to stand test (or STST) is a test consisting of performing as many sit-to-stand tests as possible in one minute, from a chair without armrests. We note before and during this test, the SpO2 (pulsed oxygen saturation) (rest value and minimum value during exercise), heart rate (HR), dyspnea on the modified Borg scale as well as the number of chair lifts performed. completely and minimum SpO2 during the recovery phase. The possible results from this one-minute test are as follows: * If SpO2 \<90% or appearance of signs of respiratory distress: Immediate stop of the test and hospitalization * SpO2 \<90% or decrease in SpO2 ≥ 4% during the test or during the recovery period: Hospitalization * SpO2 ≥90% and no decrease in SpO2 ≥ 4% during the test or during the recovery period which will be 3 minutes maximum: discharge.
Proportion of late hospitalizations, within 48 hours of first discharge from emergency department, and motivated by worsening symptoms secondary to SARS-Cov2 infection.
Time frame: 7 days
Proportion of immediate hospitalizations after the 1st admission at emergency department.
Time frame: 7 days
Proportion of adverse events related to SARS-Cov2 infection within 7 days of patient inclusion.
The adverse events identified are: * medical consultation, * readmission to the emergency department, * hospitalization, * hospitalization in intensive care unit, * death.
Time frame: 7 days
Establish the correlation between the number of chair rises performed on STST and the occurrence of an adverse event.
The adverse events identified are: * medical consultation, * readmission to the emergency department, * hospitalization, * hospitalization in intensive care unit, * death.
Time frame: 7 days
Correlation between SpO2 and the occurrence of an adverse event
the difference between the measurement of SpO2 before and after STST will be used to establish the correlation between this difference and the occurrence of an adverse event.
Time frame: 7 days
Correlation between heart rate (HR) and the occurrence of an adverse event
the difference between the measurement of HR before and after STST will be used to establish the correlation between this difference and the occurrence of an adverse event.
Time frame: 7 days
Correlation between dyspnea score and the occurrence of an adverse event
the difference between the measurement of dyspnea score before and after STST will be used to establish the correlation between this difference and the occurrence of an adverse event.
Time frame: 7 days
Plan to share: No
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This study is terminated, as verified in Nov 2022. You cannot join it, but the record below documents what was studied.
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University Hospital, Rouen