An observational study in Etiology of Hyperlactathemia, Early Period After Cardiopulmonary Bypass Surgery and Washout Phenomenon, sponsored by Acibadem University. Completed at 2 sites in Turkey. Open to participants aged 43 Years to 80 Years. Per ClinicalTrials.gov, last updated 2021-01-14.
Sponsored by Acibadem University · Observational
Objective: The objective of the study was to investigate a reverse correlation between blood lactate levels and rSO2, and distinguish between hypoxic and non-hypoxic hyperlactatemia seen in the early postoperative period.
The objective of the prospective study was to investigate a reverse correlation between blood lactate levels and rSO2, and distinguish between hypoxic and non-hypoxic hyperlactatemia seen in the early postoperative period.
Sixty American Society of Anesthesiologists (ASA) II-III patients were included in this study. Perioperative data, including age, weight, body surface area, gender, body temperature, preoperative co-morbidities, intraoperative and postoperative hemodynamic parameters, arterial blood gas analysis (ABG), cardiopulmonary bypass and aortic cross-clamp duration, flow rate, urine output, and blood product and inotropic agent usage, were recorded. Postoperative plasma lactate levels were measured simultaneously with cerebral tissue oxygen saturation (rSO2) in both cerebral hemispheres at 10 different time points.
50 studies on the registry are indexed under Hyperlactatemia; 7 are open to participants now.
This study's enrollment of 60 is below the median of 136 across 17 observational studies indexed under Hyperlactatemia.
Browse Hyperlactatemia studies →Acibadem University is the lead sponsor of 220 studies on the registry; 51 are open to participants now.
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Patients who will undergo elective bypass surgery and extracorporeal circulation
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Exclusion Criteria:
The rSO2 (cerebral oxygen satutation) was continuously monitored by NIRS (Near infrared spectroscopy) with a sensor positioned on the forehead of the patient
Differantial Diagnosis of early hyperlectathemia
To understand whether early hyperlactathemia after cardiopulmonary bypass surgery is due to hypoxic or non-hypoxic causes, we will look at the correlation between blood lactate level and cerebral oxygen saturation (rSO2)
Time frame: through study completion, an average of 1 year
Plan to share: No
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This study is completed, as verified in Jan 2021. You cannot join it, but the record below documents what was studied.
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