ClinicalTrials.gg
Status unknownNCT04670354Updated May 24, 2022

Differential Diagnosis and Cause-specific Treatment During OHCA

An observational study in Out-Of-Hospital Cardiac Arrest, sponsored by Helsinki University Central Hospital. Status unknown at 1 site in Finland. Per ClinicalTrials.gov, last updated 2022-05-24.

Sponsored by Helsinki University Central Hospital · Observational

The sponsor has not verified this record recently (last verified May 2022), so the status shown — last known as Recruiting — may be out of date.
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
100
Sex
All
01

Study summary

Differential diagnosis: ultrasound, blood gas analyse combined with examination of the patient and environment is used during Out Of Hospital Cardiac Arrest (OHCA) to screen possible underlying cause of cardiac arrest. Helicopter Emergency Medical Service (HEMS) in Helsinki has unraveled a protocol for performing differential diagnosis during OHCA. Our study aim is to test the feasibility of this protocol. Our study is a prospective medical record based study. The anesthesiologist operating in the HEMS unit fills a form after encounter of OHCA. Questioners focus on how long did execution of the protocol take, and the cause if the protocol was not completed.

02

Conditions studied

  • Out-Of-Hospital Cardiac Arrest

Keywords

  • out of hospital cardiac arrest
  • differential diagnosis
  • prospective
  • ultrasound
  • blood gas analyse
03

In context

Out-of-Hospital Cardiac Arrest

328 studies on the registry are indexed under Out-of-Hospital Cardiac Arrest; 89 are open to participants now.

This study's planned enrollment of 100 is below the median of 300 across 135 observational studies indexed under Out-of-Hospital Cardiac Arrest.

Browse Out-of-Hospital Cardiac Arrest studies →

Lead sponsor

Helsinki University Central Hospital is the lead sponsor of 311 studies on the registry; 61 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Non-traumatic out-of-hospital cardiac arrest patients encountered by the helicopter emergency medical services.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • non-traumatic out-of-hospital cardiac arrest encountered by the helicopter emergency medical services team

Exclusion criteria

Exclusion Criteria:

  • return of spontaneous circulation before HEMS crew arrival
  • termination of resuscitation attempt before HEMS crew arrival
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
100 participants (estimated)
Target follow-up
30 Days
Patient registry
Yes
06

What researchers measure

Primary outcomes

  1. Successful execution of differential diagnosis protocol

    Successful and all-inclusive execution of the following items during cardiopulmonary resuscitation: ultrasound examination, arterial blood gas analyze, clinical examination, obtaining structured history from next of kin and searching of the environment.

    Time frame: 60 minutes

Secondary outcomes

  1. Rate of cause-specific treatment during resuscitation

    Any therapy given as a treatment of presumed reversible cause of a cardiac arrest (excluding chest-compressions, ventilation, airway management, oxygen, epinephrine, amiodarone and defibrillation)

    Time frame: 60 minutes

  2. Time needed to complete the differential diagnostics protocol

    Delay from patient encountered by the prehospital critical care physician to the all diagnostics performed (during cardiopulmonary resuscitation)

    Time frame: 60 minutes

07

Study locations

1 of 1 sites recruiting
08

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 24, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT04670354
Responsible party
Jouni Nurmi, MD (docent, specialist in anesthesiology and intensive care, Helsinki University Central Hospital) — Principal investigator
First posted
Dec 17, 2020
Start date
Jan 5, 2021
Primary completion
Jun 5, 2022 (estimated)
Completion
Dec 2022 (estimated)
Last update
May 24, 2022

Study contacts

Jouni Nurmi, MD, PhD
Contact
jouni.nurmi@hus.fi
+358505951576

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in May 2022. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion