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CompletedNCT04655859Updated Dec 7, 2020

Thiol/Disulfide and Oxidative Stress

An observational study in Severe Early Childhood Caries, sponsored by Kahramanmaras Sutcu Imam University. Completed at 1 site in Turkey. Open to participants aged 3 Years to 5 Years. Per ClinicalTrials.gov, last updated 2020-12-07.

Sponsored by Kahramanmaras Sutcu Imam University · Observational

Study type
Observational
Model
Case-control
Time perspective
Cross-sectional
Enrollment
80
Ages
3 Years to 5 Years
Sex
All
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Study summary

The aim of this study was to evaluate the role of thiol/disulfide homeostasis and oxidative stress in the saliva of children with severe early childhood caries

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Conditions studied

  • Severe Early Childhood Caries
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In context

Lead sponsor

Kahramanmaras Sutcu Imam University is the lead sponsor of 192 studies on the registry; 40 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
3 Years to 5 Years
Sexes eligible
All
Sampling method
Probability sample

Study population

the children with severe early childhood caries which are 3-5 years

Inclusion criteria

  • 3-5 years

Exclusion criteria

Exclusion Criteria:

  • the children with systemic illness, using anti-inflammatory drug
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Study design

Observational model
Case-control
Time perspective
Cross-sectional
Enrollment
80 participants (actual)
Target follow-up
6 Months
Patient registry
Yes

Groups and cohorts

  • severe early childhood caries

    Diagnostic Test: saliva cotton swab

  • healthy children

    Diagnostic Test: saliva cotton swab

Interventions

  • Diagnostic testsaliva cotton swab

    evaluate the role of thiol/disulfide homeostasis and oxidative stress in the saliva of children with severe early childhood caries and healthy group

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What researchers measure

Primary outcomes

  1. thiol/disulfide homeostasis

    Unstimulated saliva samples were taken from all children. Then, thiol/disulfide homeostasis and antioxidant levels were evaluated.

    Time frame: six months

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Study locations

1 site
  • Aslı Soğukpınar
    Kahramanmaraş, Turkey
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References and documents

Individual participant data

Plan to share: Undecided — The thiol/disulfide homeostasis and antioxidant levels is to be shared in this study.

No publications or documents are linked to this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 7, 2020, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT04655859
Lead sponsor
Kahramanmaras Sutcu Imam University
Responsible party
Aslı Sogukpınar (Dr., Kahramanmaras Sutcu Imam University) — Principal investigator
First posted
Dec 7, 2020
Start date
May 10, 2020
Primary completion
Jun 10, 2020
Completion
Sep 15, 2020
Last update
Dec 7, 2020

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Nov 2020. You cannot join it, but the record below documents what was studied.

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