An observational study in Recurrent Pregnancy Loss and Preimplantation Genetic Screening, sponsored by Peking University Third Hospital. Active, not recruiting at 1 site in China. Open to female participants aged 20 Years to 45 Years. Per ClinicalTrials.gov, last updated 2020-11-09.
Sponsored by Peking University Third Hospital · Observational
STUDY AIM: to study the pregnancy outcomes and offspring development of patient with Unexplained Recurrent Pregnancy Loss Treated by PGS and spontaneous pregnancy, and to compare the health economic indicators and patient satisfaction of the two modes of pregnancy, so as to better guide the clinical treatment.
400 patients with two times or more unexplained pregnancy loss, who wants to be pregnant via preimplantation genetic screening procedure or spontaneous pregnancy are intended to be enrolled. They are going to divided into two groups: PGS(preimplantation genetic screening) group and SP(spontaneous pregnancy) group. The pregnancy outcomes and offspring development of those patients will be followed up by our investigators.
320 studies on the registry are indexed under Abortion, Spontaneous; 53 are open to participants now.
This study's planned enrollment of 400 is above the median of 200 across 140 observational studies indexed under Abortion, Spontaneous.
Browse Abortion, Spontaneous studies →Peking University Third Hospital is the lead sponsor of 735 studies on the registry; 262 are open to participants now.
Counted across the registry records on this site, refreshed daily.
patients who seek treatment in our Recurrent Pregnancy Loss clinic.
Exclusion Criteria:
patients with two times or more unexplained pregnancy loss, who wants to be pregnant via preimplantation genetic screening procedure
Procedure: Preimplantation Genetic Screening(exposure)
patients with two times or more unexplained pregnancy loss, who wants to be pregnant via spontaneous pregnancy.
Preimplantation genetic screening (PGS) was developed in the late 1980s as an alternative to prenatal diagnosis for couples at risk of transmitting a genetic or chromosomal abnormality to their children. In embryos created through in vitro fertilisation (IVF), cells are biopsied and analysed using genetic tests such as polymerase chain reaction and fluorescent in situ hybridisation (FISH).
Live birth rate
the rate of the birth of a living fetus
Time frame: 2 years of following up
Plan to share: No
This study is active, not recruiting, as verified in Nov 2020. You cannot join it, but the record below documents what was studied.
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Peking University Third Hospital