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CompletedNCT04617301Updated Nov 5, 2020

Volumetric Analysis of Resorption Types on CBCT

An observational study in Endodontic Disease and Tooth Resorption, sponsored by Recep Tayyip Erdogan University Training and Research Hospital. Completed at 1 site in Turkey. Open to participants aged 12 Years to 71 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2020-11-05.

Sponsored by Recep Tayyip Erdogan University Training and Research Hospital · Observational

Study type
Observational
Model
Case-crossover
Time perspective
Retrospective
Enrollment
43
Ages
12 Years to 71 Years
Sex
All
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Study summary

More accurate management of resorption can be achieved thanks to the three-dimensions volumetric and linear analysis, and the axial classification presented in this study.

Read the detailed description

The aim of this study was to investigate the volumetric and linear analysis, and to present the axial classification of root resorptions using cone beam computed tomography (CBCT).

A total of 43 teeth of external cervical resorption (ECR) (n=27), external replacement resorption (ERR) (n=4) and internal root resorption (IRR) (n=12) were identified from 34 patients. The volume of resorption and total tooth, the widest lengths of these resorptions, and the amount of thinnest dentin thickness around them were measured and compared according to age and sex. Additionally, the eight regional axial classification was performed and the percentages in these regions were evaluated. Significance was set at p=0.05 for statistical analysis.

More accurate management of resorption can be achieved thanks to the three-dimensions volumetric and linear analysis, and the axial classification presented in this study.

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Conditions studied

  • Endodontic Disease
  • Tooth Resorption

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Keywords

  • cone beam computed tomography
  • endodontics
  • tooth Resorption
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In context

Dental Pulp Diseases

125 studies on the registry are indexed under Dental Pulp Diseases; 38 are open to participants now.

This study's enrollment of 43 is below the median of 128 across 20 observational studies indexed under Dental Pulp Diseases.

Browse Dental Pulp Diseases studies →

Lead sponsor

Recep Tayyip Erdogan University Training and Research Hospital is the lead sponsor of 85 studies on the registry; 19 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
12 Years to 71 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Probability sample

Study population

Cases of resorption that had CBCT images were included in the study. Radiographic features of resorption were defined in the images of 34 patients in accordance with these criteria. A total of 43 teeth with ECR (n=27), ERR (n=4), and IRR (n=12) were identified from 34 patients.

Inclusion criteria

  • Cases of resorption that had CBCT images

Exclusion criteria

Exclusion Criteria:

  • those presenting pathologic lesions, congenital/developmental anomalies or teeth with root canal filling
  • those whose CBCT scans failed to present satisfactory quality.
  • Additionally, SR, TAP, and EIR cases were excluded because their true dimensions could not be completely determined before resorption.
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Study design

Observational model
Case-crossover
Time perspective
Retrospective
Enrollment
43 participants (actual)
Patient registry
No

Groups and cohorts

  • Group 1. Internal root resorption (IRR)

    Internal root resorption is the progressive destruction of intraradicular dentin and dentinal tubules along the middle and apical thirds of the canal walls as a result of clastic activities. It is seen as a radiolucent area around the pulpal cavity, usually of incisors and mandibular molars. The various etiological factors suggested for internal root resorption include traumatic injury; infection and orthodontic treatment.

  • Group 2. external cervical resorption (ECR)

    Cementum is considered to protect the underlying root dentin from being resorbed. It is broadly accepted that damage to or deficiency of this protective cementum layer below the epithelial attachment exposes the root surface to osteoclasts, which then resorb the dentin. Clinical sign; Located in cervical region of tooth Pink spot might be noted by patient/dentist Tooth usually responds positively to vitality tests unless there is pulpal involvement (in very advanced cases) Spontaneous and profuse bleeding on probing Sharp, thinned out edges around the resorptive cavity

  • Grup 3. external replacement resorption (ERR)

    external replacement resorption also known as trauma-induced resorption - and this resorption may occur in teeth that also have external inflammatory resorption. This review will not discuss external replacement resorption in detail but it will be mentioned where relevant as both types of resorption may occur in some cases. This is because replacement resorption is a consequence of the same injuries that typically cause external inflammatory resorption - such as intrusion and avulsion where there is significant damage to the external root surface during the injury, as well as sometimes during the repositioning/ replantation of the tooth.

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What researchers measure

Primary outcomes

  1. Volume of total tooth and resorbed area

    The total volume and the resorption volume were measured with used 3D semi-automatic segmentation program (ITK-SNAP 2.4)

    Time frame: for three months from the beginning of the study

  2. Measurement widest mesio-distal length, bucco-lingual length and corono-apical length of the resorbed lesion

    Linear measurement were measured with used Planmeca ProMax 3D Classic (Planmeca Promax 3D; Planmeca Oy; Helsinki, Finland)

    Time frame: for three months from the beginning of the study

  3. Linear measurements for thinnest dentin (buccal, distal, mesial and lingual/ palatinal) and resorbed area (mesio-distal length and bucco-lingual length) were made on axial sections

    Linear measurement were measured with used Planmeca ProMax 3D Classic (Planmeca Promax 3D; Planmeca Oy; Helsinki, Finland)

    Time frame: for three months from the beginning of the study

  4. The corono-apical length was measured on sagittal sections where the tooth axis was perpendicular to the ground plane.

    Linear measurement were measured with used Planmeca ProMax 3D Classic (Planmeca Promax 3D; Planmeca Oy; Helsinki, Finland)

    Time frame: for three months from the beginning of the study

  5. the axial section of the tooth was divided into eight parts and regional settlement classification was performed

    Segmentation were made with used Planmeca ProMax 3D Classic (Planmeca Promax 3D; Planmeca Oy; Helsinki, Finland)

    Time frame: for three months from the beginning of the study

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Study locations

1 site
  • Recep Tayyip Erdogan University Training and Research Hospital
    Rize, 53100, Turkey
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References and documents

Publications

  • Heithersay GS. Clinical, radiologic, and histopathologic features of invasive cervical resorption. Quintessence Int. 1999 Jan;30(1):27-37. PubMed 10323156 ↗
  • Patel S, Dawood A, Wilson R, Horner K, Mannocci F. The detection and management of root resorption lesions using intraoral radiography and cone beam computed tomography - an in vivo investigation. Int Endod J. 2009 Sep;42(9):831-8. doi: 10.1111/j.1365-2591.2009.01592.x. Epub 2009 Jul 14. PubMed 19627378 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 5, 2020, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT04617301
Lead sponsor
Recep Tayyip Erdogan University Training and Research Hospital
Responsible party
DİLARA NİL GÜNAÇAR (assistant professor, Recep Tayyip Erdogan University Training and Research Hospital) — Principal investigator
First posted
Nov 5, 2020
Start date
Jun 22, 2020
Primary completion
Aug 10, 2020
Completion
Oct 21, 2020
Last update
Nov 5, 2020

Study contacts

Dilara Nil Günaçar
study chair · Recep Tayyip Erdogan University Training and Research Hospital

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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