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Not yet recruitingNCT07752914Updated Aug 7, 2026

Radiographic Predictors of the Mandibular Lateral Lingual Canal

An observational study in Mandibular Canal Visibility, MANDIBLE and CBCT Segmentation, sponsored by Recep Tayyip Erdogan University Training and Research Hospital. Not yet recruiting. Open to participants aged 18 Years to 75 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-08-07.

Sponsored by Recep Tayyip Erdogan University Training and Research Hospital · Observational

Study type
Observational
Model
Case-control
Time perspective
Retrospective
Enrollment
210
Ages
18 Years to 75 Years
Sex
All
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Study summary

The purpose of this retrospective observational study is to investigate whether mandibular canal dimensions and sublingual fossa morphology can serve as radiographic predictors of the mandibular lateral lingual canal (MLLC) using cone-beam computed tomography (CBCT). CBCT images of adults with unilateral MLLC will be retrospectively evaluated. Mandibular canal diameter, mental foramen diameter, and sublingual fossa depth will be compared between the side with the MLLC and the contralateral side. In addition, the location, diameter, and course of the MLLC will be analyzed to identify radiographic features associated with its presence and to improve preoperative assessment for mandibular surgical procedures.

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Conditions studied

  • Mandibular Canal Visibility
  • MANDIBLE
  • CBCT Segmentation
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In context

Lead sponsor

Recep Tayyip Erdogan University Training and Research Hospital is the lead sponsor of 88 studies on the registry; 19 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 75 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

The study population will consist of adults aged 18 to 75 years with previously acquired diagnostic cone-beam computed tomography (CBCT) images archived in the Department of Oral and Maxillofacial Radiology at Recep Tayyip Erdoğan University Faculty of Dentistry. Only individuals with a unilateral mandibular lateral lingual canal (MLLC) identified on CBCT images and meeting the eligibility criteria will be included.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Individuals aged 18 to 75 years.
  • Availability of previously acquired cone-beam computed tomography (CBCT) images obtained for diagnostic purposes.
  • Presence of a unilateral mandibular lateral lingual canal (MLLC) on CBCT images.
  • CBCT images of sufficient diagnostic quality to evaluate the location, diameter, and course of the MLLC.
  • Both mandibular sides included in the same CBCT examination, allowing comparison between the side with the MLLC and the contralateral side.
  • Absence of significant motion artifacts, metal artifacts, or reconstruction errors in the regions to be measured.

Exclusion criteria

Exclusion Criteria

  • CBCT images of insufficient quality for morphometric measurement or anatomical assessment.
  • Inability to clearly identify the mandibular canal, mental foramen, MLLC, or sublingual fossa boundaries.
  • Presence of bilateral mandibular lateral lingual canals.
  • History of surgery, trauma, fracture, resection, bone grafting, or implant placement in the mandibular region under evaluation.
  • Motion or metal artifacts that prevent reliable visualization or measurement of the anatomical structures.
  • History of systemic disease or syndrome affecting craniofacial or mandibular development.
  • Presence of cystic or tumoral lesions, exostoses, or other pathological changes affecting the region of interest.
  • History of orthodontic treatment affecting the region evaluated.
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Study design

Observational model
Case-control
Time perspective
Retrospective
Enrollment
210 participants (estimated)
Patient registry
No

Groups and cohorts

  • Side With Mandibular Lateral Lingual Canal

    Adult participants with unilateral mandibular lateral lingual canal (MLLC) identified on cone-beam computed tomography (CBCT). Morphometric measurements, including mandibular canal diameter, mental foramen diameter, sublingual fossa depth, and MLLC characteristics, will be obtained from the side containing the MLLC.

  • Contralateral Side Without Mandibular Lateral Lingual Canal

    The contralateral side of the same participants without a mandibular lateral lingual canal. Morphometric measurements will be obtained using the same methodology and compared with the side containing the MLLC.

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What researchers measure

Primary outcomes

  1. Mandibular Canal Diameter

    Mandibular canal diameter will be measured in millimeters (mm) on coronal CBCT images at the level of the mandibular first molar furcation on both the side with the mandibular lateral lingual canal (MLLC) and the contralateral side. Higher values indicate a larger mandibular canal diameter.

    Time frame: Baseline (retrospective CBCT assessment)

Secondary outcomes

  1. Mental Foramen Diameter

    Mental foramen diameter will be measured in millimeters (mm) in the superoinferior direction on CBCT images on both sides. Higher values indicate a larger mental foramen diameter.

    Time frame: Baseline (retrospective CBCT assessment)

  2. Sublingual Fossa Depth

    Sublingual fossa depth will be measured in millimeters (mm) as the perpendicular distance from the deepest point of the sublingual fossa to a reference line connecting the superior and inferior borders of the lingual cortical surface. Higher values indicate a deeper sublingual fossa.

    Time frame: Baseline (retrospective CBCT assessment)

  3. Mandibular Lateral Lingual Canal Diameter

    The diameter of the mandibular lateral lingual canal (MLLC) foramen will be measured in millimeters (mm) on CBCT images. Higher values indicate a larger MLLC diameter.

    Time frame: Baseline (retrospective CBCT assessment)

  4. Mandibular Lateral Lingual Canal Location

    The anatomical location of the mandibular lateral lingual canal will be determined according to the tooth region through which the canal courses. The outcome will be reported as the frequency and percentage of canals identified in each anatomical location.

    Time frame: Baseline (retrospective CBCT assessment)

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Study locations

No study locations are listed for this record.

08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 7, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07752914
Lead sponsor
Recep Tayyip Erdogan University Training and Research Hospital
Responsible party
DİLARA NİL GÜNAÇAR (Associate Professor, Recep Tayyip Erdogan University Training and Research Hospital) — Principal investigator
First posted
Aug 7, 2026
Start date
Aug 4, 2026 (estimated)
Primary completion
Sep 10, 2026 (estimated)
Completion
Sep 30, 2026 (estimated)
Last update
Aug 7, 2026

Study contacts

dilara nil günaçar
Contact
dilaranil.tomrukcu@erdogan.edu.tr
05412940104

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.

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