An observational study in Renal Cell Carcinoma, sponsored by University Hospital, Lille. Completed at 1 site in France. Open to participants aged 18 Years to 75 Years. Per ClinicalTrials.gov, last updated 2025-12-23.
Sponsored by University Hospital, Lille · Observational
Shorten the time spent in the hospital (hospitalization duration) by optimizing the pre, per and postoperative care is of major medical and economic importance.
Minimally invasive surgery allows a faster recovery than open surgery. However, we need to ensure an early and secure return to normality in order to discharge patients safely from the hospital.
Clinical and biological parameters need to be controlled post-surgery.
This work is going to evaluate the efficacity of a fast - recovery program with incoming patients receiving minimally invasive surgery (laparoscopic or robotic) of partial and total nephrectomy.
The implementation of a medical and surgical fast-recovery program could
Prospective study of a fast recovery program evaluating the impact on the hospitalization length and the incidence of re-hospitalization for complications for 60 patients undergoing a minimally invasive nephrectomy.
The cohort will beneficiate of an extra preoperative information about the enhanced recovery after surgery program, they will benefit from a strategie of low morphine consumption during the per end post operative phase, they should need no bladder or abdominal drainage, they're encourage to eat and drink a few hours after surgery, the intravenous fluid is interrupted as early as possible, and the patients are encourage to sit, stand up and get dressed as soon as they are capable.
A form completed by the patient registers their every day capabilities to eat, drink, move, and their limitations due to pain, dizziness, and nausea. Their bowel and urine transit are also registered. This form is complete until discharge from the hospital.
Their laboratory test is monitored to identify kidney insufficiency or anemia and compared with the preoperative laboratory tests.
The hospital discharge is allowed after medical and surgical criteria are met in both groups.
A surgical evaluation is planned a week, one month, and 6 months after surgery with laboratory exams.
1 month after the discharge, a satisfaction questionnaire is filled up by the patient, answered by telephone.
At the 6 months post operative consultation, a questionnaire about chronic pain is submitted. If the patient is eligible, a chronic pain consultation is further organized.
The result will be compared to those of a retrospective cohort (+/- 60 patients) with no enhanced recovery after surgery program.
1,965 studies on the registry are indexed under Carcinoma, Renal Cell; 378 are open to participants now.
This study's enrollment of 60 is below the median of 146 across 360 observational studies indexed under Carcinoma, Renal Cell.
Browse Carcinoma, Renal Cell studies →University Hospital, Lille is the lead sponsor of 625 studies on the registry; 141 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Patients undergoing minimally invasive surgery partial or total unilateral nephrectomies
Exclusion Criteria:
undergoing a minimally invasive nephrectomy, eligible to an Enhanced Recovery After Surgery Program.
Procedure: enhanced recovery after surgery program
practice of an enhanced recovery after surgery program, according to the international reviews of literature and national recommendation
Length of hospital stay
Time frame: at 1 month
Hospital readmission rate at 1 month post surgery
Time frame: at 1 month
Postoperative antalgic consumption in Enhanced recovery after surgery patients
Time frame: through the hospitalization, up to 5 days post surgery and long term, average of 6 months post surgery
Preoperative and postoperative Creatinine and Clearance of creatinine Delta by the CKD-EPI formula
Time frame: Baseline, at 24 hours, at 1 week and at 6 months
Average Satisfaction of hospital stay and discharge on a satisfaction numerical scale
Satisfaction numerical scale from 0 to 10 : with 0 being the least satisfied possible to 0 being the most satisfied possible
Time frame: at 1 month post surgery
Neuropathic pain by Douleur Neuropathique 4 (DN4) questionnaire.
The questionnaire is made of 10 binnaire questions with "yes" or "no" answers, yes standing for 1 point, no standing for 0 point. The minimum score is 0 reflecting the absence of neuropathic pain, the maximum score is 10 reflecting the most intense neuropathic pain possible. The test is positive for the diagnosis of post surgical neuropathic pain at a score of 4 and above.
Time frame: 3 and 6 months post surgery
This study is completed, as verified in Dec 2025. You cannot join it, but the record below documents what was studied.
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University Hospital, Lille