An observational study in Rectal Cancer Stage III, sponsored by Istanbul Training and Research Hospital. Status unknown at 1 site in Turkey (Türkiye). Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2022-08-08.
Sponsored by Istanbul Training and Research Hospital · Observational
It has been shown that adipokines (resistin, leptin, adiponectin) secreted from adipose tissue and proinflammatory cytokines such as IL-6, TNF-a are associated with the risk of developing colorectal cancer. However, the role of these factors in predicting clinical response to neoadjuvant therapy in rectal cancers is unknown. In this study, the role of serum adipokine levels before neoadjuvant therapy in predicting clinical response in patients with rectal cancer is investigated. For this purpose, blood will be drawn from patients with rectal cancer who will receive neoadjuvant therapy, serum adipokines will be studied and clinical response to neoadjuvant therapy will be compared.
1,804 studies on the registry are indexed under Rectal Neoplasms; 520 are open to participants now.
This study's planned enrollment of 60 is below the median of 156 across 421 observational studies indexed under Rectal Neoplasms.
Browse Rectal Neoplasms studies →Istanbul Training and Research Hospital is the lead sponsor of 66 studies on the registry; 16 are open to participants now.
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All patients with locally advanced rectal cancer
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Exclusion Criteria:
Diagnostic Test: serum adipokines
Diagnostic Test: serum adipokines
Level of serum adipokines will be measured with flow cytometry
The Role of Serum Adipokines in Predicting Response to Neoadjuvant Therapy in Patients with Rectal Cancer
The Adiponectin, Adipsin, Leptin, Resistin levels will be measured with flow cytometric analysis.
Time frame: 1 year
Plan to share: Undecided
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This study is status unknown, as verified in Aug 2022. You cannot join it, but the record below documents what was studied.
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Istanbul Training and Research Hospital