An interventional study of Mindful After Cancer in Breast Cancer and Gynecologic Cancer, sponsored by Oregon State University. Completed at 1 site in United States. Open to female participants aged 18 Years to 89 Years. Per ClinicalTrials.gov, last updated 2025-06-25.
Sponsored by Oregon State University · Not applicable, Interventional, and Supportive care
The objectives of this study are to: 1) adapt a mindfulness-based therapy program designed to help women manage their sexual and body image concerns after cancer (Mindful After Cancer, MAC) to a videoconference format and 2) assess the feasibility, acceptability, and preliminary effects of the program among breast and gynecologic cancer survivors.
The specific aims are: 1) Assess the feasibility of the MAC program when delivered via videoconference and 2) Assess preliminary effects of the the program.
12,544 studies on the registry are indexed under Breast Neoplasms; 2,892 are open to participants now.
This study's enrollment of 22 is below the median of 72 across 9,303 interventional studies indexed under Breast Neoplasms.
Browse Breast Neoplasms studies →Oregon State University is the lead sponsor of 37 studies on the registry; 3 are open to participants now.
Of its 6 completed or terminated interventional studies of FDA-regulated products, 4 (67%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
- Stage 0 (carcinoma in situ)
Participants will be asked to attend 8 weekly sessions via videoconference, and to complete home activities and mindfulness practice between sessions.
Behavioral: Mindful After Cancer
The intervention includes eight weekly sessions (1.5-2 hours each), plus participant educational materials and audio recorded meditations, and is delivered to women in their homes via group videoconference led by a trained facilitator. Participants are asked to complete activities and mindfulness practice between sessions.
Feasibility/ Enrollment in the Study
Percentage of participants enrolled of those eligible
Time frame: Baseline (T1)
Feasibility/ Retention in the Study
Number and percentage of participants completing all assessments
Time frame: 1 month post-intervention (T2)
Feasibility/ Retention in the Intervention
Number and percentage attending at least 6 of 8 sessions
Time frame: 1 month post-intervention (T2)
Acceptability of the Intervention
Endorsement of 10 items characterizing acceptability of the intervention (e.g., the program met my expectations). Range 10-100. Higher score indicates better acceptability.
Time frame: 1 month post-intervention (T2)
Change From Baseline Interest in Sexual Activity at 1 Month
PROMIS Sexual Function and Satisfaction 2.0. 2 items. Range 2-10. Higher score indicates more interest in sexual activity.
Time frame: Baseline (T1) and 1 month post-intervention (T2)
Change From Baseline Satisfaction With Sex Life at 1 Month
New Sexual Satisfaction Scale- Short Form (NSSS-S). 12 items. Range 12-60. Higher score indicates more sexual satisfaction.
Time frame: Baseline (T1) and 1 month post-intervention (T2)
Change From Baseline Self-efficacy at 1 Month
Self-efficacy for Managing Chronic Disease Scale (adapted). 6 items. Range 6-60. Higher score indicates better self-efficacy for managing sexual health after cancer.
Time frame: Baseline (T1) and 1 month post-intervention (T2)
Change From Baseline Body Image at 1 Month
Body Image Scale. 10 items. Range 0-30. Higher score indicates poorer body image.
Time frame: Baseline (T1) and 1 month post-intervention (T2)
Change From Baseline Body Appreciation at 1 Month
Body Appreciation Scale. 13 items. Range 13-65. Higher score indicates more positive body appreciation.
Time frame: Baseline (T1) and 1 month post-intervention (T2)
Change From Baseline Anxiety at 1 Month
PROMIS Emotional Distress Anxiety Short Form 6a. 6 items. Range 6-30. Higher score indicates greater anxiety symptoms.
Time frame: Baseline (T1) and 1 month post-intervention (T2)
Change From Baseline Depression at 1 Month
Center for Epidemiologic Studies Depression Scale (CES-D). 20 items. Range 0-60. Higher score indicates greater depressive symptoms
Time frame: Baseline (T1) and 1 month post-intervention (T2)
Change in Facets of Baseline Mindfulness at 1 Month
Five-Facet Mindfulness Questionnaire (FFMQ-15). 15 items with 5 sub-scales: Observe, Describe; Act with Awareness; Non-Judgement, Non-Reactivity. Sub-scale score range 3-15. Higher score indicates greater mindfulness.
Time frame: Baseline (T1) and 1 month post-intervention (T2)
Change From Baseline Self-compassion at 1 Month
Self-Compassion Scale short form. 12 items. Total score is calculated based on mean of item responses (each item ranges 1-5). Higher mean score indicates greater self-compassion.
Time frame: Baseline (T1) and 1 month post-intervention (T2)
Change From Baseline Relationship Quality at 1 Month
Dyadic Adjustment Scale short form (DAS-7). Range 0-36. Higher score indicates more positive relationship quality
Time frame: Baseline (T1) and 1 month post-intervention (T2)
| Milestone | Mindful After Cancer |
|---|---|
| Started | 22 |
| Completed | 22 |
| Not completed | 0 |
Percentage of participants enrolled of those eligible
| Percentage enrolled of eligible | Mindful After Cancer |
|---|---|
| Feasibility/ Enrollment in the Study | 78.6 |
Number and percentage of participants completing all assessments
| Participants | Mindful After Cancer |
|---|---|
| Feasibility/ Retention in the Study | 22 |
Number and percentage attending at least 6 of 8 sessions
| Participants | Mindful After Cancer |
|---|---|
| Feasibility/ Retention in the Intervention | 18 |
Endorsement of 10 items characterizing acceptability of the intervention (e.g., the program met my expectations). Range 10-100. Higher score indicates better acceptability.
| score on a scale | Mindful After Cancer |
|---|---|
| Acceptability of the Intervention | 75.5 ± 22.9 |
PROMIS Sexual Function and Satisfaction 2.0. 2 items. Range 2-10. Higher score indicates more interest in sexual activity.
| score on a scale | Mindful After Cancer |
|---|---|
| T1 Mean, SD | 4.4 ± 1.4 |
| T2 Mean, SD | 5.0 ± 1.7 |
New Sexual Satisfaction Scale- Short Form (NSSS-S). 12 items. Range 12-60. Higher score indicates more sexual satisfaction.
| score on a scale | Mindful After Cancer |
|---|---|
| T1 Mean, SD | 35 ± 6.8 |
| T2 Mean, SD | 37.3 ± 7.4 |
Self-efficacy for Managing Chronic Disease Scale (adapted). 6 items. Range 6-60. Higher score indicates better self-efficacy for managing sexual health after cancer.
| score on a scale | Mindful After Cancer |
|---|---|
| Change From Baseline Self-efficacy at 1 Month | 0.06 (-0.87 to 0.98) |
Body Image Scale. 10 items. Range 0-30. Higher score indicates poorer body image.
| score on a scale | Mindful After Cancer |
|---|---|
| T1 Mean, SD | 15.2 ± 7.1 |
| T2 Mean, SD | 13.1 ± 8.2 |
Body Appreciation Scale. 13 items. Range 13-65. Higher score indicates more positive body appreciation.
| score on a scale | Mindful After Cancer |
|---|---|
| T1 Mean, SD | 3.2 ± 0.7 |
| T2 Mean, SD | 3.6 ± 0.7 |
PROMIS Emotional Distress Anxiety Short Form 6a. 6 items. Range 6-30. Higher score indicates greater anxiety symptoms.
| score on a scale | Mindful After Cancer |
|---|---|
| T1 Mean, SD | 15.0 ± 5.4 |
| T2 Mean, SD | 12.9 ± 4.4 |
Center for Epidemiologic Studies Depression Scale (CES-D). 20 items. Range 0-60. Higher score indicates greater depressive symptoms
| score on a scale | Mindful After Cancer |
|---|---|
| T1 Mean, SD | 16.3 ± 9.0 |
| T2 Mean, SD | 13.9 ± 11.3 |
Five-Facet Mindfulness Questionnaire (FFMQ-15). 15 items with 5 sub-scales: Observe, Describe; Act with Awareness; Non-Judgement, Non-Reactivity. Sub-scale score range 3-15. Higher score indicates greater mindfulness.
| score on a subscale | Mindful After Cancer |
|---|---|
| Observe subscale T1 Mean, SD | 10.8 ± 2.1 |
| Observe subscale T2 Mean, SD | 9.6 ± 0.9 |
| Acting with Awareness subscale T1 Mean, SD | 9.3 ± 2.0 |
| Acting with Awareness subscale T2 Mean, SD | 10.8 ± 2.2 |
| Non-reactivity subscale T1 Mean, SD | 9.7 ± 2.4 |
| Non-reactivity subscale T2 Mean, SD | 8.9 ± 1.0 |
| Non-judging subscale T1 Mean, SD | 10.7 ± 2.4 |
| Non-judging subscale T2 Mean, SD | 8.8 ± 1.4 |
| Describing subscale T1 Mean, SD | 10.3 ± 2.4 |
| Describing subscale T2 Mean, SD | 10.0 ± 1.5 |
Self-Compassion Scale short form. 12 items. Total score is calculated based on mean of item responses (each item ranges 1-5). Higher mean score indicates greater self-compassion.
| mean score on a scale | Mindful After Cancer |
|---|---|
| T1 Mean, SD | 3.0 ± 0.7 |
| T2 Mean, SD | 2.9 ± 0.2 |
Dyadic Adjustment Scale short form (DAS-7). Range 0-36. Higher score indicates more positive relationship quality
| score on a scale | Mindful After Cancer |
|---|---|
| T1 Mean, SD | 24.0 ± 6.5 |
| T2 Mean, SD | 25.3 ± 5.7 |
Collected over Duration of study, approximately 3-4 months. Non-serious events are listed at a 0% frequency threshold.
| Group | Deaths | Serious | Other |
|---|---|---|---|
| Mindful After Cancer | 0/22 (0%) | 0/22 (0%) | 0/22 (0%) |
| Age, Continuous(years) | Mindful After Cancer |
|---|---|
| Mean | 53.2 ± 9.4 |
| Sex: Female, Male(Participants) | Mindful After Cancer |
|---|---|
| Female | 22 |
| Male | 0 |
| Ethnicity (NIH/OMB)(Participants) | Mindful After Cancer |
|---|---|
| Hispanic or Latino | 1 |
| Not Hispanic or Latino | 21 |
| Unknown or Not Reported | 0 |
| Race (NIH/OMB)(Participants) | Mindful After Cancer |
|---|---|
| American Indian or Alaska Native | 0 |
| Asian | 1 |
| Native Hawaiian or Other Pacific Islander | 0 |
| Black or African American | 0 |
| White | 20 |
| More than one race | 1 |
| Unknown or Not Reported | 0 |
| Region of Enrollment(Participants) | Mindful After Cancer |
|---|---|
| United States | 22 |
| Education(Participants) | Mindful After Cancer |
|---|---|
| College graduate | 20 |
| Did not graduate from college | 2 |
| Income(Participants) | Mindful After Cancer |
|---|---|
| < $50,000 annual income | 8 |
| > $50,000 annual income | 14 |
| Employment Status(Participants) | Mindful After Cancer |
|---|---|
| Employed | 15 |
| Unemployed | 7 |
10 further baseline measures are reported on the registry.
Documents are hosted by the registry — open the source record to download them.
This study is completed, as verified in Jun 2025. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Oregon State University